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Large language models (LLMs), such as ChatGPT, have received substantial attention due to their capabilities for understanding and generating human language. While there has been a burgeoning trend in research focusing on the employment of…

Pre-trained Large Language Models (LLMs) often struggle on out-of-domain datasets like healthcare focused text. We explore specialized pre-training to adapt smaller LLMs to different healthcare datasets. Three methods are assessed:…

Computation and Language · Computer Science 2024-04-01 Niall Taylor , Dan Schofield , Andrey Kormilitzin , Dan W Joyce , Alejo Nevado-Holgado

Large language models (LLMs) are increasingly used as proxies for human judgment in computational social science, yet their ability to reproduce patterns of susceptibility to misinformation remains unclear. We test whether LLM-simulated…

Social and Information Networks · Computer Science 2026-04-13 Eun Cheol Choi , Lindsay E. Young , Emilio Ferrara

Background: Large language models (LLMs) are trained to follow directions, but this introduces a vulnerability to blindly comply with user requests even if they generate wrong information. In medicine, this could accelerate the generation…

Computation and Language · Computer Science 2024-10-01 Shan Chen , Mingye Gao , Kuleen Sasse , Thomas Hartvigsen , Brian Anthony , Lizhou Fan , Hugo Aerts , Jack Gallifant , Danielle Bitterman

Large Language Models (LLMs) are increasingly deployed in multilingual and multicultural environments where moral reasoning is essential for generating ethically appropriate responses. Yet, the dominant pretraining of LLMs on…

Computation and Language · Computer Science 2025-09-29 Sualeha Farid , Jayden Lin , Zean Chen , Shivani Kumar , David Jurgens

We study whether Large Language Models (LLMs) inherently capture domain-specific nuances in natural language. Our experiments probe the domain sensitivity of LLMs by examining their ability to distinguish queries from different domains…

Recent advances in artificial intelligence, particularly large language models LLMs, have shown promising capabilities in transforming rare disease research. This survey paper explores the integration of LLMs in the analysis of rare…

Computation and Language · Computer Science 2025-05-26 Valentina Carbonari , Pierangelo Veltri , Pietro Hiram Guzzi

Recent advances in natural language processing (NLP) can be largely attributed to the advent of pre-trained language models such as BERT and RoBERTa. While these models demonstrate remarkable performance on general datasets, they can…

We present a systematic study of medical-domain interpretability in Large Language Models (LLMs). We study how the LLMs both represent and process medical knowledge through four different interpretability techniques: (1) UMAP projections of…

Machine Learning · Computer Science 2026-02-24 Razvan Marinescu , Victoria-Elisabeth Gruber , Diego Fajardo

The rapid advancements in large language models (LLMs) have opened up new opportunities for transforming patient engagement in healthcare through conversational AI. This paper presents an overview of the current landscape of LLMs in…

Artificial Intelligence · Computer Science 2024-11-27 Bo Wen , Raquel Norel , Julia Liu , Thaddeus Stappenbeck , Farhana Zulkernine , Huamin Chen

Large language models (LLMs) are increasingly being used in user-facing applications, from providing medical consultations to job interview advice. Recent research suggests that these models are becoming increasingly proficient at inferring…

Computation and Language · Computer Science 2025-07-22 Matthew Kearney , Reuben Binns , Yarin Gal

Although large language models (LLMs) have apparently acquired a certain level of grammatical knowledge and the ability to make generalizations, they fail to interpret negation, a crucial step in Natural Language Processing. We try to…

Computation and Language · Computer Science 2023-10-25 Iker García-Ferrero , Begoña Altuna , Javier Álvez , Itziar Gonzalez-Dios , German Rigau

While large language models (LLMs) have demonstrated impressive capabilities across various natural language processing tasks by acquiring rich factual knowledge from their broad training data, their ability to synthesize and logically…

Computation and Language · Computer Science 2024-07-31 Tianshi Zheng , Jiaxin Bai , Yicheng Wang , Tianqing Fang , Yue Guo , Yauwai Yim , Yangqiu Song

Fine-tuning pre-trained large language models (LLMs) on a diverse array of tasks has become a common approach for building models that can solve various natural language processing (NLP) tasks. However, where and to what extent these models…

Computation and Language · Computer Science 2024-10-29 Zheng Zhao , Yftah Ziser , Shay B. Cohen

A common use of NLP is to facilitate the understanding of large document collections, with a shift from using traditional topic models to Large Language Models. Yet the effectiveness of using LLM for large corpus understanding in real-world…

Computation and Language · Computer Science 2025-06-05 Zongxia Li , Lorena Calvo-Bartolomé , Alexander Hoyle , Paiheng Xu , Alden Dima , Juan Francisco Fung , Jordan Boyd-Graber

There is vivid research on adapting Large Language Models (LLMs) to perform a variety of tasks in high-stakes domains such as healthcare. Despite their popularity, there is a lack of understanding of the extent and contributing factors that…

Computation and Language · Computer Science 2024-06-07 Anand Subramanian , Viktor Schlegel , Abhinav Ramesh Kashyap , Thanh-Tung Nguyen , Vijay Prakash Dwivedi , Stefan Winkler

By leveraging the retrieval of information from external knowledge databases, Large Language Models (LLMs) exhibit enhanced capabilities for accomplishing many knowledge-intensive tasks. However, due to the inherent flaws of current…

Computation and Language · Computer Science 2024-09-13 Siye Wu , Jian Xie , Jiangjie Chen , Tinghui Zhu , Kai Zhang , Yanghua Xiao

Recent advances in large language models (LLMs) have made significant progress across multiple biomedical tasks, including biomedical question answering, lay-language summarization of the biomedical literature, and clinical note…

Information Retrieval · Computer Science 2026-03-24 Deepak Gupta , Dina Demner-Fushman , William Hersh , Steven Bedrick , Kirk Roberts

The ability of large language models (LLMs) to follow natural language instructions with human-level fluency suggests many opportunities in healthcare to reduce administrative burden and improve quality of care. However, evaluating LLMs on…

While deep learning techniques have shown promising results in many natural language processing (NLP) tasks, it has not been widely applied to the clinical domain. The lack of large datasets and the pervasive use of domain-specific language…

Computation and Language · Computer Science 2019-06-20 Jiin Nam , Seunghyun Yoon , Kyomin Jung
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