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In clinical applications, the utility of segmentation models is often based on the accuracy of derived downstream metrics such as organ size, rather than by the pixel-level accuracy of the segmentation masks themselves. Thus, uncertainty…

Image and Video Processing · Electrical Eng. & Systems 2026-03-03 Matt Y. Cheung , Ashok Veeraraghavan , Guha Balakrishnan

Hyperspectral image (HSI) classification involves assigning unique labels to each pixel to identify various land cover categories. While deep classifiers have achieved high predictive accuracy in this field, they lack the ability to…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Kangdao Liu , Tianhao Sun , Hao Zeng , Yongshan Zhang , Chi-Man Pun , Chi-Man Vong

Image segmentation is a challenging task influenced by multiple sources of uncertainty, such as the data labeling process or the sampling of training data. In this paper we focus on binary segmentation and address these challenges using…

Computer Vision and Pattern Recognition · Computer Science 2025-03-10 Luca Mossina , Corentin Friedrich

Current instance segmentation models achieve high performance on average predictions, but lack principled uncertainty quantification: their outputs are not calibrated, and there is no guarantee that a predicted mask is close to the ground…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Kerri Lu , Dan M. Kluger , Stephen Bates , Sherrie Wang

Conformal Prediction (CP) is a distribution-free method for constructing prediction sets with marginal finite-sample coverage guarantees, making it a suitable framework for reliable uncertainty quantification in safety-critical object…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Christopher Ries , Moussa Kassem Sbeyti , Nicolas Bianco , Nadja Klein

The reliable deployment of deep learning in medical imaging requires uncertainty quantification that provides rigorous error guarantees while remaining anatomically meaningful. Conformal prediction (CP) is a powerful distribution-free…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Mélanie Gaillochet , Christian Desrosiers , Hervé Lombaert

Accurate uncertainty estimation is a critical need for the medical imaging community. A variety of methods have been proposed, all direct extensions of classification uncertainty estimations techniques. The independent pixel-wise…

Image and Video Processing · Electrical Eng. & Systems 2022-06-16 Thierry Judge , Olivier Bernard , Mihaela Porumb , Agis Chartsias , Arian Beqiri , Pierre-Marc Jodoin

Most semantic segmentation models treat semantic segmentation as a pixel-wise classification task and use a pixel-wise classification error as their optimization criterions. However, the pixel-wise error ignores the strong dependencies…

Computer Vision and Pattern Recognition · Computer Science 2019-10-22 Shuai Zhao , Boxi Wu , Wenqing Chu , Yao Hu , Deng Cai

Conformal prediction (CP) generates a set of predictions for a given test sample such that the prediction set almost always contains the true label (e.g., 99.5\% of the time). CP provides comprehensive predictions on possible labels of a…

Machine Learning · Computer Science 2023-09-12 Yizhe Zhang , Shuo Wang , Yejia Zhang , Danny Z. Chen

Compared to natural images, medical images usually show stronger visual patterns and therefore this adds flexibility and elasticity to resource-limited clinical applications by injecting proper priors into neural networks. In this paper, we…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Hang Zhang , Rongguang Wang , Jinwei Zhang , Dongdong Liu , Chao Li , Jiahao Li

Conformal Prediction (CP) has emerged as a powerful statistical framework for high-stakes classification applications. Instead of predicting a single class, CP generates a prediction set, guaranteed to include the true label with a…

Machine Learning · Computer Science 2025-11-25 Ariel Fargion , Lahav Dabah , Tom Tirer

Uncertainty is critical to reliable decision-making with machine learning. Conformal prediction (CP) handles uncertainty by predicting a set on a test input, hoping the set to cover the true label with at least $(1-\alpha)$ confidence. This…

Machine Learning · Computer Science 2024-03-25 Rui Xu , Yue Sun , Chao Chen , Parv Venkitasubramaniam , Sihong Xie

Reliable semantic segmentation is essential for clinical decision making, yet deep models rarely provide explicit statistical guarantees on their errors. We introduce a simple post-hoc framework that constructs confidence masks with…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Luca Mossina , Corentin Friedrich

Image segmentation algorithms can be understood as a collection of pixel classifiers, for which the outcomes of nearby pixels are correlated. Classifier models can be calibrated using Inductive Conformal Prediction, but this requires…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Joren Brunekreef , Eric Marcus , Ray Sheombarsing , Jan-Jakob Sonke , Jonas Teuwen

Reliable uncertainty quantification at unobserved spatial locations, especially in the presence of complex and heterogeneous datasets, remains a core challenge in spatial statistics. Traditional approaches like Kriging rely heavily on…

Machine Learning · Statistics 2025-02-18 Hanyang Jiang , Yao Xie

We propose a post-hoc, computationally lightweight method to quantify predictive uncertainty in semantic image segmentation. Our approach uses conformal prediction to generate statistically valid prediction sets that are guaranteed to…

Computer Vision and Pattern Recognition · Computer Science 2024-05-09 Luca Mossina , Joseba Dalmau , Léo andéol

Background and objective: Uncertainty quantification is a pivotal field that contributes to realizing reliable and robust systems. It becomes instrumental in fortifying safe decisions by providing complementary information, particularly…

Image and Video Processing · Electrical Eng. & Systems 2024-03-19 Jamil Fayyad , Shadi Alijani , Homayoun Najjaran

Background and Purpose: Glioma segmentation is crucial for clinical decisions and treatment planning. Uncertainty quantification methods, including conformal prediction (CP), can enhance segmentation models reliability. This study aims to…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Danial Elyassirad , Benyamin Gheiji , Mahsa Vatanparast , Amir Mahmoud Ahmadzadeh , Shahriar Faghani

Conformal Prediction (CP) is a principled framework for quantifying uncertainty in blackbox learning models, by constructing prediction sets with finite-sample coverage guarantees. Traditional approaches rely on scalar nonconformity scores,…

Machine Learning · Statistics 2025-05-07 Gauthier Thurin , Kimia Nadjahi , Claire Boyer

The segmentation of medical images is a fundamental step in automated clinical decision support systems. Existing medical image segmentation methods based on supervised deep learning, however, remain problematic because of their reliance on…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Euijoon Ahn , Dagan Feng , Jinman Kim
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