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Screening patients for enrollment is a well-known, labor-intensive bottleneck that leads to under-enrollment and, ultimately, trial failures. Recent breakthroughs in large language models (LLMs) offer a promising opportunity to use…

Computation and Language · Computer Science 2026-04-30 Ziyi Chen , Mengxian Lyu , Cheng Peng , Yonghui Wu

Retrieval-Augmented Generation (RAG) struggles with domain-specific enterprise datasets, often isolated behind firewalls and rich in complex, specialized terminology unseen by LLMs during pre-training. Semantic variability across domains…

Computation and Language · Computer Science 2025-08-06 Kunal Sawarkar , Shivam R. Solanki , Abhilasha Mangal

Embedding models are central to dense retrieval, semantic search, and recommendation systems, but their size often makes them impractical to deploy in resource-constrained environments such as browsers or edge devices. While smaller…

Machine learning (ML) has recently shown promising results in medical predictions using electronic health records (EHRs). However, since ML models typically have a limited capability in terms of input sizes, selecting specific medical…

Machine Learning · Computer Science 2024-07-23 Junu Kim , Chaeeun Shim , Bosco Seong Kyu Yang , Chami Im , Sung Yoon Lim , Han-Gil Jeong , Edward Choi

Biomedical text embeddings have primarily been developed using research literature from PubMed, yet clinical cardiology practice relies heavily on procedural knowledge and specialized terminology found in comprehensive textbooks rather than…

Computation and Language · Computer Science 2025-11-17 Richard J. Young , Alice M. Matthews

Biomedical Named Entity Recognition (NER) is a fundamental task of Biomedical Natural Language Processing for extracting relevant information from biomedical texts, such as clinical records, scientific publications, and electronic health…

Computation and Language · Computer Science 2023-12-27 Fahime Shahrokh , Nasser Ghadiri , Rasoul Samani , Milad Moradi

Objectives: We aim to dynamically retrieve informative demonstrations, enhancing in-context learning in multimodal large language models (MLLMs) for disease classification. Methods: We propose a Retrieval-Augmented In-Context Learning…

Artificial Intelligence · Computer Science 2025-05-06 Zaifu Zhan , Shuang Zhou , Xiaoshan Zhou , Yongkang Xiao , Jun Wang , Jiawen Deng , He Zhu , Yu Hou , Rui Zhang

Recent large language models (LLMs) have demonstrated exceptional performance on general-purpose text embedding tasks. While dense embeddings have dominated related research, we introduce the first lexicon-based embeddings (LENS) leveraging…

Computation and Language · Computer Science 2026-03-20 Yibin Lei , Tao Shen , Yu Cao , Andrew Yates

Vision-language models (VLMs) have shown strong performance on text-to-image retrieval benchmarks. However, bridging this success to real-world applications remains a challenge. In practice, human search behavior is rarely a one-shot…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Diji Yang , Minghao Liu , Chung-Hsiang Lo , Yi Zhang , James Davis

Text embedding models play a cornerstone role in AI applications, such as retrieval-augmented generation (RAG). While general-purpose text embedding models demonstrate strong performance on generic retrieval benchmarks, their effectiveness…

Information Retrieval · Computer Science 2025-10-22 Yubai Wei , Jiale Han , Yi Yang

Despite recent advancements in Multilingual Information Retrieval (MLIR), a significant gap remains between research and practical deployment. Many studies assess MLIR performance in isolated settings, limiting their applicability to…

Information Retrieval · Computer Science 2025-10-15 Vera Pavlova , Mohammed Makhlouf

Medical coding is essential for standardizing clinical data and communication but is often time-consuming and prone to errors. Traditional Natural Language Processing (NLP) methods struggle with automating coding due to the large label…

Current medical retrieval benchmarks primarily emphasize lexical or shallow semantic similarity, overlooking the reasoning-intensive demands that are central to clinical decision-making. In practice, physicians often retrieve authoritative…

Information Retrieval · Computer Science 2026-04-07 Xiangxu Zhang , Lei Li , Xiao Zhou , Zheng Liu

Patient-trial matching requires reasoning over long, heterogeneous electronic health records (EHRs) and complex eligibility criteria, posing significant challenges for scalability, generalization, and computational efficiency. Existing…

Computation and Language · Computer Science 2026-04-27 Xiaodi Li , Yang Xiao , Munhwan Lee , Konstantinos Leventakos , Young J. Juhn , David Jones , Terence T. Sio , Wei Liu , Maria Vassilaki , Nansu Zong

Deep learning models exhibit state-of-the-art performance for many predictive healthcare tasks using electronic health records (EHR) data, but these models typically require training data volume that exceeds the capacity of most healthcare…

Machine Learning · Computer Science 2018-10-24 Edward Choi , Cao Xiao , Walter F. Stewart , Jimeng Sun

Entity resolution (ER) is a fundamental task in data integration that enables insights from heterogeneous data sources. The primary challenge of ER lies in classifying record pairs as matches or nonmatches, which in multi-source ER (MS-ER)…

Databases · Computer Science 2026-04-10 Victor Christen , Peter Christen

Transfer learning has become a powerful tool to initialize deep learning models to achieve faster convergence and higher performance. This is especially useful in the medical imaging analysis domain, where data scarcity limits possible…

Computer Vision and Pattern Recognition · Computer Science 2025-04-16 Ibrahim Almakky , Santosh Sanjeev , Anees Ur Rehman Hashmi , Mohammad Areeb Qazi , Hu Wang , Mohammad Yaqub

Retrieval-Augmented Generation (RAG) offers a well-established path to grounding large language model (LLM) outputs in external knowledge, yet the question of which retrieval strategy works best in a high-stakes domain such as biomedicine…

Computation and Language · Computer Science 2026-05-05 Devi Prasad Bal , Subhashree Puhan

Artificial intelligence (AI) has significant potential in healthcare applications, but its training and deployment faces challenges due to healthcare's diverse data, complex tasks, and the need to preserve privacy. Foundation models that…

Large language models (LLMs) and large multimodal models (LMMs) promise to accelerate biomedical discovery, yet their reliability remains unclear. We introduce ARIEL (AI Research Assistant for Expert-in-the-Loop Learning), an open-source…