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Sequence alignment is a fundamental process in computational biology which identifies regions of similarity in biological sequences. With the exponential growth in the volume of data in bioinformatics databases, the time, processing power,…

Hardware Architecture · Computer Science 2025-07-31 Nasrin Akbari , Mehdi Modarressi , Alireza Khadem

The continued growth of the computational capability of throughput processors has made throughput processors the platform of choice for a wide variety of high performance computing applications. Graphics Processing Units (GPUs) are a prime…

Hardware Architecture · Computer Science 2018-05-01 Rachata Ausavarungnirun

Recent advances in graph processing on FPGAs promise to alleviate performance bottlenecks with irregular memory access patterns. Such bottlenecks challenge performance for a growing number of important application areas like machine…

Hardware Architecture · Computer Science 2022-06-20 Jonas Dann , Daniel Ritter , Holger Fröning

Offloading compute-intensive kernels to hardware accelerators relies on the large degree of parallelism offered by these platforms. However, the effective bandwidth of the memory interface often causes a bottleneck, hindering the…

Hardware Architecture · Computer Science 2022-02-25 Corentin Ferry , Tomofumi Yuki , Steven Derrien , Sanjay Rajopadhye

The availability of unprecedented unsupervised training data, along with neural scaling laws, has resulted in an unprecedented surge in model size and compute requirements for serving/training LLMs. However, the main performance bottleneck…

Machine Learning · Computer Science 2024-03-22 Amir Gholami , Zhewei Yao , Sehoon Kim , Coleman Hooper , Michael W. Mahoney , Kurt Keutzer

Memory latency, bandwidth, capacity, and energy increasingly limit performance. In this paper, we reconsider proposed system architectures that consist of huge (many-terabyte to petabyte scale) memories shared among large numbers of CPUs.…

Hardware Architecture · Computer Science 2025-09-24 Samuel Dayo , Shuhan Liu , Peijing Li , Philip Levis , Subhasish Mitra , Thierry Tambe , David Tennenhouse , H. -S. Philip Wong

Limited memory bandwidth is a critical bottleneck in modern systems. 3D-stacked DRAM enables higher bandwidth by leveraging wider Through-Silicon-Via (TSV) channels, but today's systems cannot fully exploit them due to the limited internal…

Hardware Architecture · Computer Science 2015-06-11 Donghyuk Lee , Gennady Pekhimenko , Samira Khan , Saugata Ghose , Onur Mutlu

Traditional von Neumann architecture based processors become inefficient in terms of energy and throughput as they involve separate processing and memory units, also known as~\textit{memory wall}. The memory wall problem is further…

Signal Processing · Electrical Eng. & Systems 2020-05-20 Abhash Kumar , Jawar Singh , Sai Manohar Beeraka , Bharat Gupta

As artificial intelligence (AI) and machine learning (ML) technologies disrupt a wide range of industries, cloud datacenters face ever-increasing demand in inference workloads. However, conventional CPU-based servers cannot handle excessive…

Hardware Architecture · Computer Science 2022-06-08 Jung-Hoon Kim , Sungyeob Yoo , Seungjae Moon , Joo-Young Kim

Large-scale artificial intelligence models are transforming industries and redefining human machine collaboration. However, continued scaling exposes critical limitations in hardware, including constraints on computation, bandwidth, and…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-21 Yuankai Fan , Qizhen Weng , Xuelong Li

Graph processing is typically considered to be a memory-bound rather than compute-bound problem. One common line of thought is that more available memory bandwidth corresponds to better graph processing performance. However, in this work we…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-10-10 Oded Green , James Fox , Jeffrey Young , Jun Shirako , David Bader

The increasing use of heterogeneous embedded systems with multi-core CPUs and Graphics Processing Units (GPUs) presents important challenges in effectively exploiting pipeline, task and data-level parallelism to meet throughput requirements…

Signal Processing · Electrical Eng. & Systems 2017-12-01 Shuoxin Lin , Jiahao Wu , Shuvra S. Bhattacharyya

Architectures with multiple classes of memory media are becoming a common part of mainstream supercomputer deployments. So called multi-level memories offer differing characteristics for each memory component including variation in…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-04-04 Mehmet Deveci , Simon D. Hammond , Michael M. Wolf , Sivasankaran Rajamanickam

The latest trends in high-performance computing systems show an increasing demand on the use of a large scale multicore systems in a efficient way, so that high compute-intensive applications can be executed reasonably well. However, the…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-02-25 Juliana M. N. Silva , Cristina Boeres , Lúcia M. A. Drummond , Artur A. Pessoa

Many convolutional neural network (CNN) accelerators face performance- and energy-efficiency challenges which are crucial for embedded implementations, due to high DRAM access latency and energy. Recently, some DRAM architectures have been…

Hardware Architecture · Computer Science 2023-03-06 Rachmad Vidya Wicaksana Putra , Muhammad Abdullah Hanif , Muhammad Shafique

Modern day applications have grown in size and require more computational power. The rise of machine learning and AI increased the need for parallel computation, which has increased the need for GPGPUs. With the increasing demand for…

Hardware Architecture · Computer Science 2025-03-25 Injae Shin , Blaise Tine

Sequential computation is well understood but does not scale well with current technology. Within the next decade, systems will contain large numbers of processors with potentially thousands of processors per chip. Despite this, many…

Hardware Architecture · Computer Science 2015-11-17 James Hanlon

Large language models have been widely adopted across different tasks, but their auto-regressive generation nature often leads to inefficient resource utilization during inference. While batching is commonly used to increase throughput,…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-07-14 Pol G. Recasens , Ferran Agullo , Yue Zhu , Chen Wang , Eun Kyung Lee , Olivier Tardieu , Jordi Torres , Josep Ll. Berral

Even with generational improvements in DRAM technology, memory access latency still remains the major bottleneck for application accelerators, primarily due to limitations in memory interface IPs which cannot fully account for variations in…

Hardware Architecture · Computer Science 2021-08-24 Sasindu Wijeratne , Sanket Pattnaik , Zhiyu Chen , Rajgopal Kannan , Viktor Prasanna

High level programming languages and GPU accelerators are powerful enablers for a wide range of applications. Achieving scalable vertical (within a compute node), horizontal (across compute nodes), and temporal (over different generations…

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