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To understand the black-box characteristics of deep networks, counterfactual explanation that deduces not only the important features of an input space but also how those features should be modified to classify input as a target class has…

Machine Learning · Computer Science 2022-08-15 Hong-Gyu Jung , Sin-Han Kang , Hee-Dong Kim , Dong-Ok Won , Seong-Whan Lee

Objectives: Lung cancer poses a significant global health challenge, necessitating improved prognostic methods for personalized treatment. This study introduces a censor-aware semi-supervised learning (SSL) framework that integrates…

Medical Physics · Physics 2025-06-16 Arman Gorji , Ali Fathi Jouzdani , Nima Sanati , Ren Yuan , Arman Rahmim , Mohammad R. Salmanpour

We consider after-study statistical inference for sequentially designed experiments wherein multiple units are assigned treatments for multiple time points using treatment policies that adapt over time. Our goal is to provide inference…

Machine Learning · Statistics 2025-06-10 Raaz Dwivedi , Katherine Tian , Sabina Tomkins , Predrag Klasnja , Susan Murphy , Devavrat Shah

Uncertainty quantification (UQ) has emerged as a promising approach for detecting hallucinations and low-quality output of Large Language Models (LLMs). However, obtaining proper uncertainty scores is complicated by the conditional…

We propose a method to quantify uncertainty around individual survival distribution estimates using right-censored data, compatible with any survival model. Unlike classical confidence intervals, the survival bands produced by this method…

Methodology · Statistics 2025-12-18 Matteo Sesia , Vladimir Svetnik

In the past decade, we have experienced a massive boom in the usage of digital solutions in higher education. Due to this boom, large amounts of data have enabled advanced data analysis methods to support learners and examine learning…

Machine Learning · Computer Science 2024-12-31 Mustafa Cavus , Jakub Kuzilek

In real-world machine learning systems, labels are often derived from user behaviors that the system wishes to encourage. Over time, new models must be trained as new training examples and features become available. However, feedback loops…

Machine Learning · Computer Science 2023-11-01 Victoria Lin , Louis-Philippe Morency , Dimitrios Dimitriadis , Srinagesh Sharma

The need for a large amount of labeled data in the supervised setting has led recent studies to utilize self-supervised learning to pre-train deep neural networks using unlabeled data. Many self-supervised training strategies have been…

Computer Vision and Pattern Recognition · Computer Science 2022-04-06 Mojtaba Bahrami , Mahsa Ghorbani , Nassir Navab

Large Language Models (LLMs) have become indispensable tools across various applications, making it more important than ever to ensure the quality and the trustworthiness of their outputs. This has led to growing interest in uncertainty…

Computation and Language · Computer Science 2025-09-26 Roman Vashurin , Maiya Goloburda , Preslav Nakov , Maxim Panov

In this work, we investigate unsupervised representation learning on medical time series, which bears the promise of leveraging copious amounts of existing unlabeled data in order to eventually assist clinical decision making. By evaluating…

Machine Learning · Computer Science 2018-12-04 Xinrui Lyu , Matthias Hueser , Stephanie L. Hyland , George Zerveas , Gunnar Raetsch

Counterfactual explanations suggest what should be different in the input instance to change the outcome of an AI system. When dealing with counterfactual explanations in the field of Predictive Process Monitoring, however, control flow…

Artificial Intelligence · Computer Science 2025-08-26 Andrei Buliga , Chiara Di Francescomarino , Chiara Ghidini , Ivan Donadello , Fabrizio Maria Maggi

In reinforcement learning (RL), it is challenging to learn directly from high-dimensional observations, where data augmentation has recently been shown to remedy this via encoding invariances from raw pixels. Nevertheless, we empirically…

Machine Learning · Computer Science 2023-12-20 Chenyu Sun , Hangwei Qian , Chunyan Miao

Unlike traditional supervised learning, in many settings only partial feedback is available. We may only observe outcomes for the chosen actions, but not the counterfactual outcomes associated with other alternatives. Such settings…

Machine Learning · Computer Science 2021-12-09 Ruijiang Gao , Max Biggs , Wei Sun , Ligong Han

Concept-based learning enhances prediction accuracy and interpretability by leveraging high-level, human-understandable concepts. However, existing CBL frameworks do not address survival analysis tasks, which involve predicting event times…

Machine Learning · Computer Science 2025-02-11 Stanislav R. Kirpichenko , Lev V. Utkin , Andrei V. Konstantinov , Natalya M. Verbova

Although numerous complex algorithms for treatment effect estimation have been developed in recent years, their effectiveness remains limited when handling insufficiently labeled training sets due to the high cost of labeling the effect…

Machine Learning · Computer Science 2025-05-09 Hechuan Wen , Tong Chen , Mingming Gong , Li Kheng Chai , Shazia Sadiq , Hongzhi Yin

To achieve the goal of providing the best possible care to each patient, physicians need to customize treatments for patients with the same diagnosis, especially when treating diseases that can progress further and require additional…

Methodology · Statistics 2022-10-25 Xiao Li , Brent R Logan , S M Ferdous Hossain , Erica E M Moodie

Mediation analysis is a useful tool to evaluate surrogate endpoints in clinical trials. We propose a novel method, the M-survival learner, for estimating heterogeneous indirect treatment effects in the presence of censored outcomes. The…

Methodology · Statistics 2026-04-16 Xingyu Li , Qing Liu , Xun Jiang , Hong Amy Xia , Brian P. Hobbs , Peng Wei

Counterfactual inference provides a mathematical framework for reasoning about hypothetical outcomes under alternative interventions, bridging causal reasoning and predictive modeling. We present a counterfactual inference framework for…

Machine Learning · Computer Science 2025-10-22 Jingya Cheng , Alaleh Azhir , Jiazi Tian , Hossein Estiri

This paper introduces a simple framework of counterfactual estimation for causal inference with time-series cross-sectional data, in which we estimate the average treatment effect on the treated by directly imputing counterfactual outcomes…

Methodology · Statistics 2022-08-16 Licheng Liu , Ye Wang , Yiqing Xu

Counterfactual explanations (CFEs) provide human-centric interpretability by identifying the minimal, actionable changes required to alter a machine learning model's prediction. Therefore, CFs can be used as (i) interventions for…

Machine Learning · Computer Science 2026-04-21 Shovito Barua Soumma , Asiful Arefeen , Stephanie M. Carpenter , Melanie Hingle , Hassan Ghasemzadeh
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