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Phylogenetic networks are notoriously difficult to reconstruct. Here we suggest that it can be useful to view unknown genetic distance along edges in phylogenetic networks as analogous to unknown resistance in electric circuits. This…

Combinatorics · Mathematics 2020-10-01 Stefan Forcey , Drew Scalzo

In this paper, we lay the groundwork on the comparison of phylogenetic networks based on edge contractions and expansions as edit operations, as originally proposed by Robinson and Foulds to compare trees. We prove that these operations…

Data Structures and Algorithms · Computer Science 2025-02-21 Bertrand Marchand , Nadia Tahiri , Olivier Tremblay-Savard , Manuel Lafond

Phylogenetic networks are important for the study of evolution. The number of methods to find such networks is increasing, but most such methods can only reconstruct small networks. To find bigger networks, one can attempt to combine small…

Discrete Mathematics · Computer Science 2019-12-10 Remie Janssen , Mark Jones , Yukihiro Murakami

Construction of phylogenetic trees has traditionally focused on binary trees where all species appear on leaves, a problem for which numerous efficient solutions have been developed. Certain application domains though, such as viral…

Data Structures and Algorithms · Computer Science 2016-11-01 Dimitris Papamichail , Angela Huang , Andrew Miller , Edward Kennedy , Jan-Lucas Ott , Georgios Papamichail

Phylogenetic mixtures model the inhomogeneous molecular evolution commonly observed in data. The performance of phylogenetic reconstruction methods where the underlying data is generated by a mixture model has stimulated considerable recent…

Populations and Evolution · Quantitative Biology 2007-06-30 Frederick A. Matsen , Mike Steel

Often questions arise about old or extinct networks. What proteins interacted in a long-extinct ancestor species of yeast? Who were the central players in the Last.fm social network 3 years ago? Our ability to answer such questions has been…

Molecular Networks · Quantitative Biology 2015-05-19 Saket Navlakha , Carl Kingsford

Recently, there has been a growing interest in the relationships between unrooted and rooted phylogenetic networks. In this context, a natural question to ask is if an unrooted phylogenetic network U can be oriented as a rooted phylogenetic…

Populations and Evolution · Quantitative Biology 2024-01-17 Janosch Döcker , Simone Linz

Popular methods for exploring the space of rooted phylogenetic trees use rearrangement moves such as rNNI (rooted Nearest Neighbour Interchange) and rSPR (rooted Subtree Prune and Regraft). Recently, these moves were generalized to rooted…

Combinatorics · Mathematics 2021-01-01 Remie Janssen , Mark Jones , Péter L. Erdős , Leo van Iersel , Celine Scornavacca

Evolutionary relationships between species are usually represented in phylogenies, i.e. evolutionary trees, which are a type of networks. The terminal nodes of these trees represent species, which are made of individuals and populations…

Populations and Evolution · Quantitative Biology 2007-07-11 E. Hernandez-Garcia , E. A. Herrada , A. F. Rozenfeld , C. J. Tessone , V. M. Eguiluz , C. M. Duarte , S. Arnaud-Haond , E. Serrao

A normal (phylogenetic) network with $k$ reticulations displays $2^k$ phylogenetic trees. In this paper, we establish an analogous result for tree-child (phylogenetic) networks with no underlying $3$-cycles. In particular, we show that a…

Combinatorics · Mathematics 2025-08-20 Charles Semple , Kristina Wicke

Phylogenetic networks are increasingly being considered as better suited to represent the complexity of the evolutionary relationships between species. One class of phylogenetic networks that has received a lot of attention recently is the…

Data Structures and Algorithms · Computer Science 2023-05-02 Kaari Landry , Olivier Tremblay-Savard , Manuel Lafond

The problem of constructing an optimal rooted phylogenetic network from a set of rooted triplets is an NP-hard problem. In this paper, we present a heuristic algorithm called TripNet which tries to construct an optimal rooted phylogenetic…

Data Structures and Algorithms · Computer Science 2012-01-19 Hadi Poormohammadi , Changiz Eslahchi , Ruzbeh Tusserkani

We review the recent fast progress in statistical physics of evolving networks. Interest has focused mainly on the structural properties of random complex networks in communications, biology, social sciences and economics. A number of giant…

Statistical Mechanics · Physics 2015-06-24 S. N. Dorogovtsev , J. F. F. Mendes

The Tree of Life is the graphical structure that represents the evolutionary process from single-cell organisms at the origin of life to the vast biodiversity we see today. Reconstructing this tree from genomic sequences is challenging due…

Populations and Evolution · Quantitative Biology 2020-10-06 Claudia Solis-Lemus , Arrigo Coen , Cecile Ane

In previous work, we gave asymptotic counting results for the number of tree-child and normal networks with $k$ reticulation vertices and explicit exponential generating functions of the counting sequences for $k=1,2,3$. The purpose of this…

Combinatorics · Mathematics 2021-03-05 Michael Fuchs , Bernhard Gittenberger , Marefatollah Mansouri

We introduce a biologically natural, mathematically tractable model of random phylogenetic network to describe evolution in the presence of hybridization. One of the features of this model is that the hybridization rate of the lineages…

Probability · Mathematics 2024-02-27 François Bienvenu , Jean-Jil Duchamps

We propose a novel method for the inference of phylogenetic trees that utilises point configurations on hyperbolic space as its optimisation landscape. Each taxon corresponds to a point of the point configuration, while the evolutionary…

Machine Learning · Computer Science 2021-06-07 Benjamin Wilson

We consider the problem of estimating the evolutionary history of a set of species (phylogeny or species tree) from several genes. It is known that the evolutionary history of individual genes (gene trees) might be topologically distinct…

Populations and Evolution · Quantitative Biology 2016-11-18 Gautam Dasarathy , Robert Nowak , Sebastien Roch

Understanding the origins of complexity is a fundamental challenge with implications for biological and technological systems. Network theory emerges as a powerful tool to model complex systems. Networks are an intuitive framework to…

Disordered Systems and Neural Networks · Physics 2024-10-22 Blai Vidiella , Salva Duran-Nebreda , Sergi Valverde

The rich and varied ways that genetic material can be passed between species has motivated extensive research into the theory of phylogenetic networks. Features that align with biological processes, or with desirable mathematical…

Populations and Evolution · Quantitative Biology 2025-08-12 Andrew Francis