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Language has long been conceived as an essential tool for human reasoning. The breakthrough of Large Language Models (LLMs) has sparked significant research interest in leveraging these models to tackle complex reasoning tasks. Researchers…

Automatic disease diagnosis has become increasingly valuable in clinical practice. The advent of large language models (LLMs) has catalyzed a paradigm shift in artificial intelligence, with growing evidence supporting the efficacy of LLMs…

Recovering the structure of causal graphical models from observational data is an essential yet challenging task for causal discovery in scientific scenarios. Domain-specific causal discovery usually relies on expert validation or prior…

Artificial Intelligence · Computer Science 2025-08-27 Taiyu Ban , Lyuzhou Chen , Derui Lyu , Xiangyu Wang , Qinrui Zhu , Qiang Tu , Huanhuan Chen

Objectieve:This review aims to deliver a comprehensive analysis of Large Language Models (LLMs) utilization in mental health care, evaluating their effectiveness, identifying challenges, and exploring their potential for future application.…

Objectives: To evaluate the current limitations of large language models (LLMs) in medical question answering, focusing on the quality of datasets used for their evaluation. Materials and Methods: Widely-used benchmark datasets, including…

Computation and Language · Computer Science 2025-07-15 Mahmoud Alwakeel , Aditya Nagori , Vijay Krishnamoorthy , Rishikesan Kamaleswaran

Acute poly-substance intoxication requires rapid, life-saving decisions under substantial uncertainty, as clinicians must rely on incomplete ingestion details and nonspecific symptoms. Effective diagnostic reasoning in this chaotic…

Computation and Language · Computer Science 2026-04-01 Nico Oberländer , David Bani-Harouni , Tobias Zellner , Nassir Navab , Florian Eyer , Matthias Keicher

Large Language Models (LLMs) are increasingly utilized in AI-driven educational instruction and assessment, particularly within mathematics education. The capability of LLMs to generate accurate answers and detailed solutions for math…

Artificial Intelligence · Computer Science 2025-08-15 Liang Zhang , Edith Aurora Graf

While Small Language Models (SLMs) have demonstrated promising performance on an increasingly wide array of commonsense reasoning benchmarks, current evaluation practices rely almost exclusively on the accuracy of their final answers,…

Computation and Language · Computer Science 2026-04-21 Francesco Maria Molfese , Luca Moroni , Ciro Porcaro , Simone Conia , Roberto Navigli

Current Large Language Models (LLMs) exhibit significant limitations, notably in structured, interpretable, and verifiable medical reasoning, alongside practical deployment challenges related to computational resources and data privacy.…

Computation and Language · Computer Science 2025-06-06 Boqin Zhuang , Chenxiao Song , Huitong Lu , Jiacheng Qiao , Mingqian Liu , Mingxing Yu , Ping Hong , Rui Li , Xiaoxia Song , Xiangjun Xu , Xu Chen , Yaoyao Ma , Yujie Gao

Systematic reviews (SR), in which experts summarize and analyze evidence across individual studies to provide insights on a specialized topic, are a cornerstone for evidence-based clinical decision-making, research, and policy. Given the…

Computation and Language · Computer Science 2025-05-30 Christopher Polzak , Alejandro Lozano , Min Woo Sun , James Burgess , Yuhui Zhang , Kevin Wu , Serena Yeung-Levy

The emergence of groundbreaking large language models capable of performing complex reasoning tasks holds significant promise for addressing various scientific challenges, including those arising in complex clinical scenarios. To enable…

Computation and Language · Computer Science 2025-05-30 Yakun Zhu , Zhongzhen Huang , Linjie Mu , Yutong Huang , Wei Nie , Jiaji Liu , Shaoting Zhang , Pengfei Liu , Xiaofan Zhang

The advent of large reasoning models, such as OpenAI o1 and DeepSeek R1, has significantly advanced complex reasoning tasks. However, their capabilities in multilingual complex reasoning remain underexplored, with existing efforts largely…

Computation and Language · Computer Science 2025-05-27 Wenyang Luo , Wayne Xin Zhao , Jing Sha , Shijin Wang , Ji-Rong Wen

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

Large language models are often assumed to acquire increasingly structured, generalizable internal representations simply by scaling data and parameters. We interrogate this assumption by introducing a Clinical Trial Natural Language…

Artificial Intelligence · Computer Science 2025-08-15 Maël Jullien , Marco Valentino , André Freitas

Large language models (LLMs) have demonstrated their remarkable performance across various language understanding tasks. While emerging benchmarks have been proposed to evaluate LLMs in various domains such as mathematics and computer…

Artificial Intelligence · Computer Science 2024-10-28 Junnan Dong , Zijin Hong , Yuanchen Bei , Feiran Huang , Xinrun Wang , Xiao Huang

Large Language Models (LLMs) have achieved remarkable performance on a wide range of Natural Language Processing (NLP) benchmarks, often surpassing human-level accuracy. However, their reliability in high-stakes domains such as medicine,…

The emergence of various medical large language models (LLMs) in the medical domain has highlighted the need for unified evaluation standards, as manual evaluation of LLMs proves to be time-consuming and labor-intensive. To address this…

Computation and Language · Computer Science 2023-12-21 Yan Cai , Linlin Wang , Ye Wang , Gerard de Melo , Ya Zhang , Yanfeng Wang , Liang He

Large language models (LLMs) are increasingly explored for clinical decision support, yet most evaluations are conducted in English, leaving their reliability in other languages uncertain. Here we evaluate the impact of prompting language…

Computation and Language · Computer Science 2026-05-20 Adrien Bazoge , Josselin Corvellec , Sofiane Djillali Sid-Ahmed , Pierre-Antoine Gourraud

This study assesses the ability of state-of-the-art large language models (LLMs) including GPT-3.5, GPT-4, Falcon, and LLaMA 2 to identify patients with mild cognitive impairment (MCI) from discharge summaries and examines instances where…

Bridging clinical diagnostic reasoning with AI remains a central challenge in medical imaging. We introduce MedCLM, an automated pipeline that converts detection datasets into large-scale medical visual question answering (VQA) data with…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Soo Yong Kim , Suin Cho , Vincent-Daniel Yun , Gyeongyeon Hwang