English
Related papers

Related papers: MOSAIK: Multi-Origin Spatial Transcriptomics Analy…

200 papers

Speckle-based phase-contrast X-ray imaging (SB-PCXI) can reconstruct high-resolution images of weakly-attenuating materials that would otherwise be indistinguishable in conventional attenuation-based imaging. The experimental setup of…

Medical Physics · Physics 2023-07-31 Samantha J. Alloo , Kaye S. Morgan , David M. Paganin , Konstantin M. Pavlov

Existing image foundation models are not optimized for spherical images having been trained primarily on perspective images. PanoSAMic integrates the pre-trained Segment Anything (SAM) encoder to make use of its extensive training and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Mahdi Chamseddine , Didier Stricker , Jason Rambach

Spatially resolved transcriptomics is a fast-developing set of technologies that enables the measurement of localized gene expression across spatial locations in a sample. Detecting spatially varying genes is critical for analyzing such…

Applications · Statistics 2026-04-22 Pritam Dey , Rajarshi Guhaniyogi , Yang Ni , Bani K. Mallick

Spatial Transcriptomics enables mapping of gene expression within its native tissue context, but current platforms measure only a limited set of genes due to experimental constraints and excessive costs. To overcome this, computational…

Genomics · Quantitative Biology 2025-11-20 Amit Kumar , Maninder Kaur , Raghvendra Mall , Sukrit Gupta

Speaker-Attributed, Time-Stamped Transcription (SATS) aims to transcribe what is said and to precisely determine the timing of each speaker, which is particularly valuable for meeting transcription. Existing SATS systems rarely adopt an…

The advancement of Spatial Transcriptomics (ST) has facilitated the spatially-aware profiling of gene expressions based on histopathology images. Although ST data offers valuable insights into the micro-environment of tumors, its…

Computer Vision and Pattern Recognition · Computer Science 2024-12-23 Hongyi Wang , Xiuju Du , Jing Liu , Shuyi Ouyang , Yen-Wei Chen , Lanfen Lin

Single-cell-resolution spatial transcriptomics profiles gene expression at cellular locations in native tissues, yet accurate cell-type annotation remains challenging: imaging-based platforms are constrained by targeted gene panels, whereas…

Cell Behavior · Quantitative Biology 2026-05-27 Yiyang Zhang , Bokai Zhao , Xiaoru Zhang , Zongchang Du , Xiaojuan Sun , Tianzi Jiang

Spatial transcriptomics (ST) reveals spatial heterogeneity of gene expression, yet its resolution is limited by current platforms. Recent methods enhance resolution via H&E-stained histology, but three major challenges persist: (1)…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Xuepeng Liu , Zheng Jiang , Pinan Zhu , Hanyu Liu , Chao Li

We present MOSAIC-GS, a novel, fully explicit, and computationally efficient approach for high-fidelity dynamic scene reconstruction from monocular videos using Gaussian Splatting. Monocular reconstruction is inherently ill-posed due to the…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Svitlana Morkva , Maximum Wilder-Smith , Michael Oechsle , Alessio Tonioni , Marco Hutter , Vaishakh Patil

Machine learning applications on signals such as computer vision or biomedical data often face significant challenges due to the variability that exists across hardware devices or session recordings. This variability poses a Domain…

Machine Learning · Computer Science 2024-07-22 Théo Gnassounou , Antoine Collas , Rémi Flamary , Karim Lounici , Alexandre Gramfort

The rapid advancement of spatial transcriptomics (ST), i.e., spatial gene expressions, has made it possible to measure gene expression within original tissue, enabling us to discover molecular mechanisms. However, current ST platforms…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Xiaofei Wang , Stephen Price , Chao Li

Quantitative characterization of cellular spatial organization is critical for understanding tumor progression and immune response. Recent advances in artificial intelligence (AI) enable large-scale segmentation and classification of nuclei…

Accurate and efficient simulation of room impulse responses is crucial for spatial audio applications. However, existing acoustic ray-tracing tools often operate as black boxes and only output impulse responses (IRs), providing limited…

Sound · Computer Science 2025-03-25 Yongyi Zang , Qiuqiang Kong

Improving the detailed understanding of the underlying properties and functions of biomolecules has recently attracted growing interest, enabled by the possibility of real-space imaging of single, intact macromolecules using Scanning…

Mesoscale and Nanoscale Physics · Physics 2026-03-10 Tim J. Seifert , Dhaneesh Kumar , Markus Etzkorn , Stephan Rauschenbach , Klaus Kern , Kelvin Anggara , Uta Schlickum

Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima

Podocytes, specialized epithelial cells that envelop the glomerular capillaries, play a pivotal role in maintaining renal health. The current description and quantification of features on pathology slides are limited, prompting the need for…

Quantitative Methods · Quantitative Biology 2023-08-15 Jiayuan Chen , Yu Wang , Ruining Deng , Quan Liu , Can Cui , Tianyuan Yao , Yilin Liu , Jianyong Zhong , Agnes B. Fogo , Haichun Yang , Shilin Zhao , Yuankai Huo

We introduce MOSAIC, a Python program for machine learning models. Our framework is developed with in mind accelerating machine learning studies through making implementing and testing arbitrary network architectures and data sets simpler,…

Machine Learning · Computer Science 2023-01-31 Mattéo Papin , Yann Beaujeault-Taudière , Frédéric Magniette

Ortholog detection (OD) is a critical step for comparative genomic analysis of protein-coding sequences. In this paper, we begin with a comprehensive comparison of four popular, methodologically diverse OD methods: MultiParanoid, Blat,…

Populations and Evolution · Quantitative Biology 2014-04-22 M. Cyrus Maher , Ryan D. Hernandez

Monoaural audio source separation is a challenging research area in machine learning. In this area, a mixture containing multiple audio sources is given, and a model is expected to disentangle the mixture into isolated atomic sources. In…

Machine Learning · Computer Science 2019-11-25 Amir Zadeh , Tianjun Ma , Soujanya Poria , Louis-Philippe Morency

While pathology foundation models have transformed cancer image analysis, they often lack integration with molecular data at single-cell resolution, limiting their utility for precision oncology. Here, we present PAST, a pan-cancer…

Quantitative Methods · Quantitative Biology 2025-07-10 Changchun Yang , Haoyang Li , Yushuai Wu , Yilan Zhang , Yifeng Jiao , Yu Zhang , Rihan Huang , Yuan Cheng , Yuan Qi , Xin Guo , Xin Gao