English
Related papers

Related papers: Prot2Text-V2: Protein Function Prediction with Mul…

200 papers

Protein research is crucial in various fundamental disciplines, but understanding their intricate structure-function relationships remains challenging. Recent Large Language Models (LLMs) have made significant strides in comprehending…

Computational Engineering, Finance, and Science · Computer Science 2025-01-24 Chao Wang , Hehe Fan , Ruijie Quan , Yi Yang

Retrieving homologous protein sequences is essential for a broad range of protein modeling tasks such as fitness prediction, protein design, structure modeling, and protein-protein interactions. Traditional workflows have relied on a…

Quantitative Methods · Quantitative Biology 2025-06-11 Ruben Weitzman , Peter Mørch Groth , Lood Van Niekerk , Aoi Otani , Yarin Gal , Debora Marks , Pascal Notin

Multi-channel video-language retrieval require models to understand information from different channels (e.g. video$+$question, video$+$speech) to correctly link a video with a textual response or query. Fortunately, contrastive multimodal…

Computer Vision and Pattern Recognition · Computer Science 2023-04-12 Xudong Lin , Simran Tiwari , Shiyuan Huang , Manling Li , Mike Zheng Shou , Heng Ji , Shih-Fu Chang

Multimodal protein language models deliver strong performance on mutation-effect prediction, but training such models from scratch demands substantial computational resources. In this paper, we propose a fine-tuning framework called…

Quantitative Methods · Quantitative Biology 2026-02-02 Junde Xu , Yapin Shi , Lijun Lang , Taoyong Cui , Zhiming Zhang , Guangyong Chen , Jiezhong Qiu , Pheng-Ann Heng

Proteins, essential to biological systems, perform functions intricately linked to their three-dimensional structures. Understanding the relationship between protein structures and their amino acid sequences remains a core challenge in…

Quantitative Methods · Quantitative Biology 2024-11-04 Liang He , Peiran Jin , Yaosen Min , Shufang Xie , Lijun Wu , Tao Qin , Xiaozhuan Liang , Kaiyuan Gao , Yuliang Jiang , Tie-Yan Liu

Recent advances in multimodal techniques have led to significant progress in Medical Visual Question Answering (Med-VQA). However, most existing models focus on global image features rather than localizing disease-specific regions crucial…

Computational Engineering, Finance, and Science · Computer Science 2025-06-30 Yuan Wang , Jiaxiang Liu , Shujian Gao , Bin Feng , Zhihang Tang , Xiaotang Gai , Jian Wu , Zuozhu Liu

Pre-training of text and layout has proved effective in a variety of visually-rich document understanding tasks due to its effective model architecture and the advantage of large-scale unlabeled scanned/digital-born documents. We propose…

Computation and Language · Computer Science 2022-01-11 Yang Xu , Yiheng Xu , Tengchao Lv , Lei Cui , Furu Wei , Guoxin Wang , Yijuan Lu , Dinei Florencio , Cha Zhang , Wanxiang Che , Min Zhang , Lidong Zhou

The recent advent of self-supervised pre-training techniques has led to a surge in the use of multimodal learning in form document understanding. However, existing approaches that extend the mask language modeling to other modalities…

Cross-modal text-molecule retrieval model aims to learn a shared feature space of the text and molecule modalities for accurate similarity calculation, which facilitates the rapid screening of molecules with specific properties and…

Information Retrieval · Computer Science 2024-11-01 Jia Song , Wanru Zhuang , Yujie Lin , Liang Zhang , Chunyan Li , Jinsong Su , Song He , Xiaochen Bo

Vision-language models pre-trained on large scale of unlabeled biomedical images and associated reports learn generalizable semantic representations. These multi-modal representations can benefit various downstream tasks in the biomedical…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Xinliu Zhong , Kayhan Batmanghelich , Li Sun

In this paper we present the Process-To-Text (P2T) framework for the automatic generation of textual descriptive explanations of processes. P2T integrates three AI paradigms: process mining for extracting temporal and structural information…

Computation and Language · Computer Science 2023-05-24 Yago Fontenla-Seco , Alberto Bugarín-Diz , Manuel Lama

Recently, vision-language joint representation learning has proven to be highly effective in various scenarios. In this paper, we specifically adapt vision-language joint learning for scene text detection, a task that intrinsically involves…

Computer Vision and Pattern Recognition · Computer Science 2022-05-02 Sibo Song , Jianqiang Wan , Zhibo Yang , Jun Tang , Wenqing Cheng , Xiang Bai , Cong Yao

Contrastive learning has been demonstrated to be effective in enhancing pre-trained language models (PLMs) to derive superior universal sentence embeddings. However, existing contrastive methods still have two limitations. Firstly, previous…

Computation and Language · Computer Science 2022-10-11 Yuxin Jiang , Linhan Zhang , Wei Wang

Designing proteins that satisfy natural language functional requirements is a central goal in protein engineering. A straightforward baseline is to fine-tune generic instruction-tuned LLMs as direct text-to-sequence generators, but this is…

Quantitative Methods · Quantitative Biology 2026-04-21 Yutang Ge , Guojiang Zhao , Sihang Li , Zheng Cheng , Zifeng Zhao , Hanchen Xia , Guolin Ke , Linfeng Zhang , Zhifeng Gao , Yuguang Wang

AlphaFold2 (AF2) has transformed protein structure prediction by harnessing co-evolutionary constraints embedded in multiple sequence alignments (MSAs). MSAs not only encode static structural information, but also hold critical details…

Biomolecules · Quantitative Biology 2025-03-04 Enming Xing , Junjie Zhang , Shen Wang , Xiaolin Cheng

Recently developed deep learning techniques have significantly improved the accuracy of various speech and image recognition systems. In this paper we adapt some of these techniques for protein secondary structure prediction. We first train…

Machine Learning · Computer Science 2016-11-07 Akosua Busia , Jasmine Collins , Navdeep Jaitly

Protein design is a fundamental challenge in biotechnology, aiming to design novel sequences with specific functions within the vast space of possible proteins. Recent advances in deep generative models have enabled function-based protein…

Machine Learning · Computer Science 2025-10-15 Nuowei Liu , Jiahao Kuang , Yanting Liu , Tao Ji , Changzhi Sun , Man Lan , Yuanbin Wu

Protein homology search underlies function annotation, structure prediction, and evolutionary analysis, but remains challenging in the "twilight zone," where global sequence similarity is weak and classical alignment methods lose…

Machine Learning · Computer Science 2026-05-29 Gabrielle Cohn , Rohan Gumaste , Minh Hoang , Vihan Lakshman

Edit-based approaches have recently shown promising results on multiple monolingual sequence transduction tasks. In contrast to conventional sequence-to-sequence (Seq2Seq) models, which learn to generate text from scratch as they are…

Computation and Language · Computer Science 2022-05-11 Kostiantyn Omelianchuk , Vipul Raheja , Oleksandr Skurzhanskyi

This paper presents methods of making using of text supervision to improve the performance of sequence-to-sequence (seq2seq) voice conversion. Compared with conventional frame-to-frame voice conversion approaches, the seq2seq acoustic…

Sound · Computer Science 2020-01-14 Jing-Xuan Zhang , Zhen-Hua Ling , Yuan Jiang , Li-Juan Liu , Chen Liang , Li-Rong Dai
‹ Prev 1 3 4 5 6 7 10 Next ›