Related papers: Prot2Text-V2: Protein Function Prediction with Mul…
Protein research is crucial in various fundamental disciplines, but understanding their intricate structure-function relationships remains challenging. Recent Large Language Models (LLMs) have made significant strides in comprehending…
Retrieving homologous protein sequences is essential for a broad range of protein modeling tasks such as fitness prediction, protein design, structure modeling, and protein-protein interactions. Traditional workflows have relied on a…
Multi-channel video-language retrieval require models to understand information from different channels (e.g. video$+$question, video$+$speech) to correctly link a video with a textual response or query. Fortunately, contrastive multimodal…
Multimodal protein language models deliver strong performance on mutation-effect prediction, but training such models from scratch demands substantial computational resources. In this paper, we propose a fine-tuning framework called…
Proteins, essential to biological systems, perform functions intricately linked to their three-dimensional structures. Understanding the relationship between protein structures and their amino acid sequences remains a core challenge in…
Recent advances in multimodal techniques have led to significant progress in Medical Visual Question Answering (Med-VQA). However, most existing models focus on global image features rather than localizing disease-specific regions crucial…
Pre-training of text and layout has proved effective in a variety of visually-rich document understanding tasks due to its effective model architecture and the advantage of large-scale unlabeled scanned/digital-born documents. We propose…
The recent advent of self-supervised pre-training techniques has led to a surge in the use of multimodal learning in form document understanding. However, existing approaches that extend the mask language modeling to other modalities…
Cross-modal text-molecule retrieval model aims to learn a shared feature space of the text and molecule modalities for accurate similarity calculation, which facilitates the rapid screening of molecules with specific properties and…
Vision-language models pre-trained on large scale of unlabeled biomedical images and associated reports learn generalizable semantic representations. These multi-modal representations can benefit various downstream tasks in the biomedical…
In this paper we present the Process-To-Text (P2T) framework for the automatic generation of textual descriptive explanations of processes. P2T integrates three AI paradigms: process mining for extracting temporal and structural information…
Recently, vision-language joint representation learning has proven to be highly effective in various scenarios. In this paper, we specifically adapt vision-language joint learning for scene text detection, a task that intrinsically involves…
Contrastive learning has been demonstrated to be effective in enhancing pre-trained language models (PLMs) to derive superior universal sentence embeddings. However, existing contrastive methods still have two limitations. Firstly, previous…
Designing proteins that satisfy natural language functional requirements is a central goal in protein engineering. A straightforward baseline is to fine-tune generic instruction-tuned LLMs as direct text-to-sequence generators, but this is…
AlphaFold2 (AF2) has transformed protein structure prediction by harnessing co-evolutionary constraints embedded in multiple sequence alignments (MSAs). MSAs not only encode static structural information, but also hold critical details…
Recently developed deep learning techniques have significantly improved the accuracy of various speech and image recognition systems. In this paper we adapt some of these techniques for protein secondary structure prediction. We first train…
Protein design is a fundamental challenge in biotechnology, aiming to design novel sequences with specific functions within the vast space of possible proteins. Recent advances in deep generative models have enabled function-based protein…
Protein homology search underlies function annotation, structure prediction, and evolutionary analysis, but remains challenging in the "twilight zone," where global sequence similarity is weak and classical alignment methods lose…
Edit-based approaches have recently shown promising results on multiple monolingual sequence transduction tasks. In contrast to conventional sequence-to-sequence (Seq2Seq) models, which learn to generate text from scratch as they are…
This paper presents methods of making using of text supervision to improve the performance of sequence-to-sequence (seq2seq) voice conversion. Compared with conventional frame-to-frame voice conversion approaches, the seq2seq acoustic…