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Text classification is one of the most imperative tasks in natural language processing (NLP). Recent advances with pre-trained language models (PLMs) have shown remarkable success on this task. However, the satisfying results obtained by…

Computation and Language · Computer Science 2023-08-30 Jianing Wang , Chengyu Wang , Cen Chen , Ming Gao , Jun Huang , Aoying Zhou

Predicting the structure of interacting chains is crucial for understanding biological systems and developing new drugs. Large-scale pre-trained Protein Language Models (PLMs), such as ESM2, have shown impressive abilities in extracting…

Biomolecules · Quantitative Biology 2023-12-05 Shuxian Zou , Hui Li , Shentong Mo , Xingyi Cheng , Eric Xing , Le Song

Medical visual question answering (VQA) is a challenging task that requires answering clinical questions of a given medical image, by taking consider of both visual and language information. However, due to the small scale of training data…

Computer Vision and Pattern Recognition · Computer Science 2023-07-12 Pengfei Li , Gang Liu , Jinlong He , Zixu Zhao , Shenjun Zhong

The remarkable progress of Multi-modal Large Language Models (MLLMs) has attracted significant attention due to their superior performance in visual contexts. However, their capabilities in turning visual figure to executable code, have not…

Computation and Language · Computer Science 2024-05-14 Chengyue Wu , Yixiao Ge , Qiushan Guo , Jiahao Wang , Zhixuan Liang , Zeyu Lu , Ying Shan , Ping Luo

Pose-estimation methods enable extracting human motion from common videos in the structured form of 3D skeleton sequences. Despite great application opportunities, effective content-based access to such spatio-temporal motion data is a…

Computer Vision and Pattern Recognition · Computer Science 2024-07-03 Nicola Messina , Jan Sedmidubsky , Fabrizio Falchi , Tomáš Rebok

In contrast to their remarkable performance on general knowledge QA, the true abilities of Large Language Models (LLMs) in tasks demanding deep, specialized reasoning, such as in protein biology, have yet to be thoroughly investigated.…

Quantitative Methods · Quantitative Biology 2025-12-30 Dingyi Rong , Zijian Chen , Qi Jia , Kaiwei Zhang , Haotian Lu , Guangtao Zhai , Ning Liu

Recent progress in vision-language pretraining has enabled significant improvements to many downstream computer vision applications, such as classification, retrieval, segmentation and depth prediction. However, a fundamental capability…

Dense retrieval calls for discriminative embeddings to represent the semantic relationship between query and document. It may benefit from the using of large language models (LLMs), given LLMs' strong capability on semantic understanding.…

Computation and Language · Computer Science 2025-11-25 Zheng Liu , Chaofan Li , Shitao Xiao , Yingxia Shao , Defu Lian

We propose Context-Adaptive Multi-Prompt Embedding, a novel approach to enrich semantic representations in vision-language contrastive learning. Unlike standard CLIP-style models that rely on a single text embedding, our method introduces…

Machine Learning · Computer Science 2025-08-07 Dahun Kim , Anelia Angelova

For multilingual sequence-to-sequence pretrained language models (multilingual Seq2Seq PLMs), e.g. mBART, the self-supervised pretraining task is trained on a wide range of monolingual languages, e.g. 25 languages from CommonCrawl, while…

Computation and Language · Computer Science 2022-09-22 Changtong Zan , Liang Ding , Li Shen , Yu Cao , Weifeng Liu , Dacheng Tao

Research on speech-to-speech translation (S2ST) has progressed rapidly in recent years. Many end-to-end systems have been proposed and show advantages over conventional cascade systems, which are often composed of recognition, translation…

Computation and Language · Computer Science 2022-11-17 Xinjian Li , Ye Jia , Chung-Cheng Chiu

Deep learning has brought significant improvements to the field of cross-modal representation learning. For tasks such as text-to-speech (TTS), voice conversion (VC), and automatic speech recognition (ASR), a cross-modal fine-grained…

Audio and Speech Processing · Electrical Eng. & Systems 2025-05-29 Chunyu Qiang , Wang Geng , Yi Zhao , Ruibo Fu , Tao Wang , Cheng Gong , Tianrui Wang , Qiuyu Liu , Jiangyan Yi , Zhengqi Wen , Chen Zhang , Hao Che , Longbiao Wang , Jianwu Dang , Jianhua Tao

Protein-protein bindings play a key role in a variety of fundamental biological processes, and thus predicting the effects of amino acid mutations on protein-protein binding is crucial. To tackle the scarcity of annotated mutation data,…

Quantitative Methods · Quantitative Biology 2024-05-20 Lirong Wu , Yijun Tian , Haitao Lin , Yufei Huang , Siyuan Li , Nitesh V Chawla , Stan Z. Li

We present a framework for optimizing prompts in vision-language models to elicit multimodal reasoning without model retraining. Using an evolutionary algorithm to guide prompt updates downstream of visual tasks, our approach improves upon…

Computation and Language · Computer Science 2025-04-01 Sid Bharthulwar , John Rho , Katrina Brown

Activation steering has emerged as a promising approach for efficiently adapting large language models (LLMs) to downstream behaviors. However, most existing steering methods rely on a single static direction per task or concept, making…

The Protein Secondary Structure Visualizer ProS2Vi is a novel Python-based visualization tool designed to enhance the analysis and accessibility of protein secondary structures calculated and identified by the Dictionary of Secondary…

Biomolecules · Quantitative Biology 2024-08-08 Luckman Qasim , Laleh Alisaraie

The goal of protein representation learning is to extract knowledge from protein databases that can be applied to various protein-related downstream tasks. Although protein sequence, structure, and function are the three key modalities for…

Biomolecules · Quantitative Biology 2024-05-14 Eunji Ko , Seul Lee , Minseon Kim , Dongki Kim

Deep learning has become a crucial tool in studying proteins. While the significance of modeling protein structure has been discussed extensively in the literature, amino acid types are typically included in the input as a default operation…

Quantitative Methods · Quantitative Biology 2024-07-01 Yang Tan , Lirong Zheng , Bozitao Zhong , Liang Hong , Bingxin Zhou

Bimodal software analysis initially appeared to be within reach with the advent of large language models. Unfortunately, the complex interplay of natural language text and code in software engineering, presents unique challenges that…

Software Engineering · Computer Science 2024-10-25 Xunzhu Tang , Liran Wang , Yonghui Liu , Linzheng Chai , Jian Yang , Zhoujun Li , Haoye Tian , Jacques Klein , Tegawende F. Bissyande

We propose the novel adaptation of a pre-trained seq2seq model for readability assessment. We prove that a seq2seq model - T5 or BART - can be adapted to discern which text is more difficult from two given texts (pairwise). As an…

Computation and Language · Computer Science 2024-06-18 Bruce W. Lee , Jason Hyung-Jong Lee
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