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Strongly supervised learning requires detailed knowledge of truth labels at instance levels, and in many machine learning applications this is a major drawback. Multiple instance learning (MIL) is a popular weakly supervised learning method…

Machine Learning · Computer Science 2022-02-18 Saul Fuster , Trygve Eftestøl , Kjersti Engan

We present a novel class incremental learning approach based on deep neural networks, which continually learns new tasks with limited memory for storing examples in the previous tasks. Our algorithm is based on knowledge distillation and…

Machine Learning · Computer Science 2022-04-05 Minsoo Kang , Jaeyoo Park , Bohyung Han

Whole Slide Imaging (WSI) has become a gold standard in cancer diagnosis, inspecting multi-scale information from cellular to tissue levels. Processing an entire WSI directly is infeasible due to GPU memory constraints; thus, Multiple…

Image and Video Processing · Electrical Eng. & Systems 2026-05-08 Tianyi Zhang , Sicheng Chen , Borui Kang , Dankai Liao , Qiaochu Xue , Bochong Zhang , Fei Xia , Zeyu Liu , Yueming Jin

Early diagnosis of lung cancer is a key intervention for the treatment of lung cancer computer aided diagnosis (CAD) can play a crucial role. However, most published CAD methods treat lung cancer diagnosis as a lung nodule classification…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Junhua Chen , Haiyan Zeng , Chong Zhang , Zhenwei Shi , Andre Dekker , Leonard Wee , Inigo Bermejo

Attention-based multiple instance learning (AMIL) algorithms have proven to be successful in utilizing gigapixel whole-slide images (WSIs) for a variety of different computational pathology tasks such as outcome prediction and cancer…

Brain lesion segmentation from multi-modal MRI often assumes fixed modality sets or predefined pathologies, making existing models difficult to adapt across cohorts and imaging protocols. Continual learning (CL) offers a natural solution…

Image and Video Processing · Electrical Eng. & Systems 2026-01-21 Yousef Sadegheih , Dorit Merhof , Pratibha Kumari

Deep learning architectures have shown remarkable results in scene understanding problems, however they exhibit a critical drop of performances when they are required to learn incrementally new tasks without forgetting old ones. This…

Computer Vision and Pattern Recognition · Computer Science 2021-01-22 Umberto Michieli , Pietro Zanuttigh

Incremental learning attempts to develop a classifier which learns continuously from a stream of data segregated into different classes. Deep learning approaches suffer from catastrophic forgetting when learning classes incrementally, while…

Computer Vision and Pattern Recognition · Computer Science 2020-07-31 Ali Ayub , Alan Wagner

Continual learning (CL) aims to learn new tasks without erasing previous knowledge. However, current CL methods primarily emphasize improving accuracy while often neglecting training efficiency, which consequently restricts their practical…

Machine Learning · Computer Science 2026-01-30 RuiQi Liu , Boyu Diao , Libo Huang , Zijia An , Hangda Liu , Zhulin An , Yongjun Xu

Healthcare clinics regularly encounter dynamic data that changes due to variations in patient populations, treatment policies, medical devices, and emerging disease patterns. Deep learning models can suffer from catastrophic forgetting when…

Machine Learning · Computer Science 2023-11-09 Amritpal Singh , Mustafa Burak Gurbuz , Shiva Souhith Gantha , Prahlad Jasti

Semi-supervised medical image segmentation has attracted much attention in recent years because of the high cost of medical image annotations. In this paper, we propose a novel Inherent Consistent Learning (ICL) method, aims to learn robust…

Computer Vision and Pattern Recognition · Computer Science 2023-04-19 Ye Zhu , Jie Yang , Si-Qi Liu , Ruimao Zhang

We propose Spatial-Aware Correlated Multiple Instance Learning (SAC-MIL) for performing WSI classification. SAC-MIL consists of a positional encoding module to encode position information and a SAC block to perform full instance…

Computer Vision and Pattern Recognition · Computer Science 2025-09-05 Yu Bai , Zitong Yu , Haowen Tian , Xijing Wang , Shuo Yan , Lin Wang , Honglin Li , Xitong Ling , Bo Zhang , Zheng Zhang , Wufan Wang , Hui Gao , Xiangyang Gong , Wendong Wang

Multiple-instance Learning (MIL) is commonly used to undertake computational pathology (CPath) tasks, and the use of multi-scale patches allows diverse features across scales to be learned. Previous studies using multi-scale features in…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Shuyang Wu , Yifu Qiu , Ines P. Nearchou , Sandrine Prost , Jonathan A Fallowfield , Hakan Bilen , Timothy J Kendall

Class-Incremental Learning (CIL) trains a model to continually recognize new classes from non-stationary data while retaining learned knowledge. A major challenge of CIL arises when applying to real-world data characterized by non-uniform…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Jiangpeng He , Fengqing Zhu

The task of Long-tailed Class Incremental Learning (LT-CIL) addresses the sequential learning of new classes from datasets with imbalanced class distributions. This scenario intensifies the fundamental problem of catastrophic forgetting,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Taigo Sakai , Kazuhiro Hotta

Exemplar-free class-incremental learning (EFCIL) aims to mitigate catastrophic forgetting in class-incremental learning (CIL) without available historical training samples as exemplars. Compared with its exemplar-based CIL counterpart that…

Machine Learning · Computer Science 2025-12-18 Run He , Di Fang , Yizhu Chen , Kai Tong , Cen Chen , Yi Wang , Lap-pui Chau , Huiping Zhuang

Multiple instance learning (MIL) is often used in medical imaging to classify high-resolution 2D images by processing patches or classify 3D volumes by processing slices. However, conventional MIL approaches treat instances separately,…

Machine Learning · Computer Science 2025-11-13 Ethan Harvey , Dennis Johan Loevlie , Michael C. Hughes

Whole Slide Image (WSI) analysis is a powerful method to facilitate the diagnosis of cancer in tissue samples. Automating this diagnosis poses various issues, most notably caused by the immense image resolution and limited annotations. WSIs…

Computer Vision and Pattern Recognition · Computer Science 2023-04-19 Ahmet Gokberk Gul , Oezdemir Cetin , Christoph Reich , Tim Prangemeier , Nadine Flinner , Heinz Koeppl

Multiple Instance Learning (MIL) has been widely applied in histopathology to classify Whole Slide Images (WSIs) with slide-level diagnoses. While the ground truth is established by expert pathologists, the slides can be difficult to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Marie Arrivat , Rémy Peyret , Elsa Angelini , Pietro Gori

The size and the computational load of fine-tuning large-scale pre-trained neural network are becoming two major obstacles in adopting machine learning in many applications. Continual learning (CL) can serve as a remedy through enabling…

Machine Learning · Computer Science 2023-03-28 Yuliang Cai , Jesse Thomason , Mohammad Rostami