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We revisit the SICA (Susceptible-Infectious-Chronic-AIDS) mathematical model for transmission dynamics of the human immunodeficiency virus (HIV) with varying population size in a homogeneously mixing population. We consider SICA models…

Populations and Evolution · Quantitative Biology 2020-08-10 Cristiana J. Silva , Delfim F. M. Torres

Epidemics have shaped human history, often with devastating consequences, motivating the development of mathematical models to understand and control their dynamics. Among the many aspects of epidemic behavior, the conditions that lead to…

Populations and Evolution · Quantitative Biology 2026-05-01 Germano Hartmann Brill , Pablo Enrique Jurado Silvestrin , Sebastian Gonçalves

This paper is concerned with the well-posedness and optimal control problem of a reaction-diffusion system for an epidemic Susceptible-Infected-Recovered-Susceptible (SIRS) mathematical model in which the dynamics develops in a spatially…

Optimization and Control · Mathematics 2023-04-24 Pierluigi Colli , Gianni Gilardi , Gabriela Marinoschi , Elisabetta Rocca

We introduce a modified SIR model with memory for the dynamics of epidemic spreading in a constant population of individuals. Each individual is in one of the states susceptible (${\bf S}$), infected (${\bf I}$) or recovered (${\bf R}$). In…

Populations and Evolution · Quantitative Biology 2022-03-03 Michael Bestehorn , Thomas M. Michelitsch , Bernard A. Collet , Alejandro P. Riascos , Andrzej F. Nowakowski

In this paper we investigate the asymptotic behavior of some SIR models incorporating demography, bounded random transmission coefficient and a time-dependent vaccination strategy targeting the susceptible population. In this setting, we…

Populations and Evolution · Quantitative Biology 2025-10-27 Javier López-de-la-Cruz , Susana Merchán , Felipe Rivero , Javier Rodrigo

Many disease models focus on characterizing the underlying transmission mechanism but make simple, possibly naive assumptions about how infections are reported. In this note, we use a simple deterministic Susceptible-Infected-Removed (SIR)…

Populations and Evolution · Quantitative Biology 2019-11-28 Sang Woo Park , Benjamin M. Bolker

Motivated by the ongoing pandemic COVID-19, we propose a closed-loop framework that combines inference from testing data, learning the parameters of the dynamics and optimal resource allocation for controlling the spread of the…

Physics and Society · Physics 2021-04-27 Ashish R. Hota , Jaydeep Godbole , Philip E Paré

Compartmental transmission models have become an invaluable tool to study the dynamics of infectious diseases. The Susceptible-Infectious-Recovered (SIR) model is known to have an exact semi-analytical solution. In the current study, the…

Populations and Evolution · Quantitative Biology 2020-11-03 Kevin Heng , Christian L. Althaus

In this study, we present an integro-differential model to simulate the local spread of infections. The model incorporates a standard susceptible-infected-recovered (\textit{SIR}-) model enhanced by an integral kernel, allowing for…

Dynamical Systems · Mathematics 2023-07-20 Moritz Schäfer , Karol Niedzielewski , Thomas Götz , Tyll Krüger

We measure the effect of different public health regulations to the spread of COVID-19, based on a SEIRA model -- a SEIR model including asymptomatic transmissions. The cumulative confirmed cases and death show nonlinear positive…

Populations and Evolution · Quantitative Biology 2020-04-15 Weijie Pang

The ever-changing world of disease study heavily relies on mathematical models. They are key in finding and controlling infectious diseases. We aim to explore these mathematical tools used for studying disease spread in biology. The SEIR…

History and Overview · Mathematics 2025-01-03 Pabel Shahrear , Md. Shahedul Islam , Md. Abu Bakkar , Anika Bushra , Ismail Hossain

The effect of spatial correlations on the spread of infectious diseases was investigated using a stochastic SIR (Susceptible-Infective-Recovered) model on complex networks. It was found that in addition to the reduction of the effective…

Populations and Evolution · Quantitative Biology 2007-05-23 J. Verdasca , M. M. Telo da Gama , A. Nunes , N. R. Bernardino , J. M. Pacheco , M. C. Gomes

Networks of contacts capable of spreading infectious diseases are often observed to be highly heterogeneous, with the majority of individuals having fewer contacts than the mean, and a significant minority having relatively very many…

Physics and Society · Physics 2016-12-21 César Parra-Rojas , Thomas House , Alan J. McKane

In this paper, we consider a compartmental SIRS epidemic model with asymptomatic infection and seasonal succession, which is a periodic discontinuous differential system. The basic reproduction number $\mathcal{R}_0$ is defined and valuated…

Dynamical Systems · Mathematics 2017-08-15 Yilei Tang , Dongmei Xiao , Weinian Zhang , Di Zhu

We consider in this paper a general SEIRS model describing the dynamics of an infectious disease including latency, waning immunity and infection-induced mortality. We derive an infinite system of differential equations that provides an…

Optimization and Control · Mathematics 2022-01-26 Marcel Fang , Pierre-Alexandre Bliman

In this paper we explore a time-depended SEIR model, in which the dynamics of the infection in four groups from a selected target group (population), divided according to the infection, are modeled by a system of nonlinear ordinary…

Populations and Evolution · Quantitative Biology 2021-03-31 Svetozar Margenov , Nedyu Popivanov , Iva Ugrinova , Stanislav Harizanov , Tsvetan Hristov

This paper is concerned with a stochastic model for the spread of an SEIR (susceptible -> exposed (=latent) -> infective -> removed) epidemic with a contact tracing scheme, in which removed individuals may name some of their infectious…

Probability · Mathematics 2015-12-08 Frank G Ball , Edward S Knock , Philip D O'Neill

We formulate a generalized susceptible exposed infectious recovered (SEIR) model on a graph, describing the population dynamics of an open crowded place with an arbitrary topology. As a sample calculation, we discuss three simple cases,…

Physics and Society · Physics 2020-12-18 Andrea Nava , Alessandro Papa , Marco Rossi , Domenico Giuliano

Human to human transmissible infectious diseases spread in a population using human interactions as its transmission vector. The early stages of such an outbreak can be modeled by a graph whose edges encode these interactions between…

Populations and Evolution · Quantitative Biology 2020-06-11 Goncalo Oliveira

The global pandemic of the 2019-nCov requires the evaluation of policy interventions to mitigate future social and economic costs of quarantine measures worldwide. We propose an epidemiological model for forecasting and policy evaluation…

Applications · Statistics 2020-10-30 Philip Nadler , Shuo Wang , Rossella Arcucci , Xian Yang , Yike Guo