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As AI systems become more advanced, ensuring their alignment with a diverse range of individuals and societal values becomes increasingly critical. But how can we capture fundamental human values and assess the degree to which AI systems…

Human-Computer Interaction · Computer Science 2025-11-05 Hua Shen , Tiffany Knearem , Reshmi Ghosh , Yu-Ju Yang , Nicholas Clark , Tanushree Mitra , Yun Huang

The application scope of Large Language Models (LLMs) continues to expand, leading to increasing interest in personalized LLMs that align with human values. However, aligning these models with individual values raises significant safety…

Computation and Language · Computer Science 2025-06-10 Sooyung Choi , Jaehyeok Lee , Xiaoyuan Yi , Jing Yao , Xing Xie , JinYeong Bak

Medical question answering (QA) benchmarks often focus on multiple-choice or fact-based tasks, leaving open-ended answers to real patient questions underexplored. This gap is particularly critical in mental health, where patient questions…

Computation and Language · Computer Science 2026-05-15 Yahan Li , Jifan Yao , John Bosco S. Bunyi , Adam C. Frank , Angel Hsing-Chi Hwang , Ruishan Liu

The proliferation of Large Language Models (LLMs) presents transformative potential for healthcare, yet practical deployment is hindered by the absence of frameworks that assess real-world clinical utility. Existing benchmarks test static…

The wide exploration of large language models (LLMs) raises the awareness of alignment between healthcare stakeholder preferences and model outputs. This alignment becomes a crucial foundation to empower the healthcare workflow effectively,…

Computers and Society · Computer Science 2025-05-07 Kexin Ding , Mu Zhou , Akshay Chaudhari , Shaoting Zhang , Dimitris N. Metaxas

With the proliferation of Large Language Models (LLMs) in diverse domains, there is a particular need for unified evaluation standards in clinical medical scenarios, where models need to be examined very thoroughly. We present CliMedBench,…

Computation and Language · Computer Science 2024-10-07 Zetian Ouyang , Yishuai Qiu , Linlin Wang , Gerard de Melo , Ya Zhang , Yanfeng Wang , Liang He

Rapid integration of large language models (LLMs) into societal applications has intensified concerns about their alignment with universal ethical principles, as their internal value representations remain opaque despite behavioral…

Computation and Language · Computer Science 2025-05-26 Yi Su , Jiayi Zhang , Shu Yang , Xinhai Wang , Lijie Hu , Di Wang

The rise of large language models (LLMs) has shifted time series analysis from narrow analytics to general-purpose reasoning. Yet, existing benchmarks cover only a small set of health time series modalities and tasks, failing to reflect the…

Machine Learning · Computer Science 2026-03-17 Sirui Li , Shuhan Xiao , Mihir Joshi , Ahmed Metwally , Daniel McDuff , Wei Wang , Yuzhe Yang

Existing benchmarks for evaluating the clinical reasoning capabilities of large language models (LLMs) often lack a clear definition of "clinical reasoning" as a construct, fail to capture the full breadth of interdependent tasks within a…

Large language models (LLMs) show significant potential in healthcare, prompting numerous benchmarks to evaluate their capabilities. However, concerns persist regarding the reliability of these benchmarks, which often lack clinical…

Computation and Language · Computer Science 2026-04-30 Wenting Chen , Guo Yu , Yiu-Fai Cheung , Meidan Ding , Jie Liu , Zizhan Ma , Wenxuan Wang , Linlin Shen

Trustworthiness in healthcare question-answering (QA) systems is important for ensuring patient safety, clinical effectiveness, and user confidence. As large language models (LLMs) become increasingly integrated into medical settings, the…

Computation and Language · Computer Science 2025-11-04 Yinuo Wang , Baiyang Wang , Robert E. Mercer , Frank Rudzicz , Sudipta Singha Roy , Pengjie Ren , Zhumin Chen , Xindi Wang

The remarkable capabilities of Large Language Models (LLMs) make them increasingly compelling for adoption in real-world healthcare applications. However, the risks associated with using LLMs in medical applications have not been…

Multimodal large language models (MLLMs) hold significant potential in medical applications, including disease diagnosis and clinical decision-making. However, these tasks require highly accurate, context-sensitive, and professionally…

Computation and Language · Computer Science 2025-09-01 Meidan Ding , Jipeng Zhang , Wenxuan Wang , Cheng-Yi Li , Wei-Chieh Fang , Hsin-Yu Wu , Haiqin Zhong , Wenting Chen , Linlin Shen

Large language models (LLMs) show promise for clinical use. They are often evaluated using datasets such as MedQA. However, Many medical datasets, such as MedQA, rely on simplified Question-Answering (Q\A) that underrepresents real-world…

Computation and Language · Computer Science 2025-10-24 Yunpeng Xiao , Carl Yang , Mark Mai , Xiao Hu , Kai Shu

Large Language Models (LLMs) are transforming diverse fields and gaining increasing influence as human proxies. This development underscores the urgent need for evaluating value orientations and understanding of LLMs to ensure their…

Computation and Language · Computer Science 2024-06-07 Yuanyi Ren , Haoran Ye , Hanjun Fang , Xin Zhang , Guojie Song

Large Language Models (LLMs) are increasingly being explored for clinical question answering and decision support, yet safe deployment critically requires reliable handling of patient measurements in heterogeneous clinical notes. Existing…

Computation and Language · Computer Science 2026-04-16 Minh-Vuong Nguyen , Fatemeh Shiri , Zhuang Li , Karin Verspoor

Recent advances in Retrieval-Augmented Generation (RAG) have enabled large language models (LLMs) to ground outputs in clinical evidence. However, connecting LLMs with external databases introduces the risk of contextual leakage: a subtle…

Computation and Language · Computer Science 2026-03-17 Shaowei Guan , Yu Zhai , Hin Chi Kwok , Jiawei Du , Xinyu Feng , Jing Li , Harry Qin , Vivian Hui

With generative artificial intelligence (AI), particularly large language models (LLMs), continuing to make inroads in healthcare, it is critical to supplement traditional automated evaluations with human evaluations. Understanding and…

Large language models (LLMs) are increasingly used for medical consultation and health information support. In this high-stakes setting, safety depends not only on medical knowledge, but also on how models respond when patient inputs are…

Computation and Language · Computer Science 2026-04-01 Yahan Li , Xinyi Jie , Wanjia Ruan , Xubei Zhang , Huaijie Zhu , Yicheng Gao , Chaohao Du , Ruishan Liu