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For Large Language Models (LLMs), a disconnect persists between benchmark performance and real-world utility. Current evaluation frameworks remain fragmented, prioritizing technical metrics while neglecting holistic assessment for…

Artificial Intelligence · Computer Science 2025-11-19 Jun Wang , Ninglun Gu , Kailai Zhang , Zijiao Zhang , Yelun Bao , Jin Yang , Xu Yin , Liwei Liu , Yihuan Liu , Pengyong Li , Gary G. Yen , Junchi Yan

Large language models (LLMs) are widely deployed for open-ended communication, yet most bias evaluations still rely on English, classification-style tasks. We introduce \corpusname, a new multilingual, debate-style benchmark designed to…

Computation and Language · Computer Science 2026-03-31 Muhammed Saeed , Muhammad Abdul-mageed , Shady Shehata

Large Language Model (LLM) alignment aims to ensure that LLM outputs match with human values. Researchers have demonstrated the severity of alignment problems with a large spectrum of jailbreak techniques that can induce LLMs to produce…

Computation and Language · Computer Science 2024-02-06 Xiaolong Jin , Zhuo Zhang , Xiangyu Zhang

The complexity and heterogeneity of data in many real-world applications pose significant challenges for traditional machine learning and signal processing techniques. For instance, in medicine, effective analysis of diverse physiological…

Machine Learning · Computer Science 2024-08-16 Nimeesha Chan , Felix Parker , William Bennett , Tianyi Wu , Mung Yao Jia , James Fackler , Kimia Ghobadi

Large language models (LLMs) have demonstrated powerful text generation capabilities, bringing unprecedented innovation to the healthcare field. While LLMs hold immense promise for applications in healthcare, applying them to real clinical…

Computation and Language · Computer Science 2023-10-16 Rui Yang , Edison Marrese-Taylor , Yuhe Ke , Lechao Cheng , Qingyu Chen , Irene Li

Objectives: While Large Language Models (LLMs) have been widely used to assist clinicians and support patients, no existing work has explored dialogue systems for standard diagnostic interviews and assessments. This study aims to bridge the…

Computation and Language · Computer Science 2025-05-01 Sichang Tu , Abigail Powers , Stephen Doogan , Jinho D. Choi

Doctors and patients alike increasingly use Large Language Models (LLMs) to diagnose clinical cases. However, unlike domains such as math or coding, where correctness can be objectively defined by the final answer, medical diagnosis…

Computation and Language · Computer Science 2025-05-21 Kevin Wu , Eric Wu , Rahul Thapa , Kevin Wei , Angela Zhang , Arvind Suresh , Jacqueline J. Tao , Min Woo Sun , Alejandro Lozano , James Zou

Recent advancements in Large Language Models (LLMs) have significantly enhanced interactions between users and models. These advancements concurrently underscore the need for rigorous safety evaluations due to the manifestation of social…

Computation and Language · Computer Science 2025-03-26 Dahyun Jung , Seungyoon Lee , Hyeonseok Moon , Chanjun Park , Heuiseok Lim

The deployment of Large Language Models (LLMs) in high-stakes clinical settings demands rigorous and reliable evaluation. However, existing medical benchmarks remain static, suffering from two critical limitations: (1) data contamination,…

Artificial Intelligence · Computer Science 2026-02-12 Zhiling Yan , Dingjie Song , Zhe Fang , Yisheng Ji , Xiang Li , Quanzheng Li , Lichao Sun

Large language models (LLMs) are capable of many natural language tasks, yet they are far from perfect. In health applications, grounding and interpreting domain-specific and non-linguistic data is crucial. This paper investigates the…

Computation and Language · Computer Science 2024-04-30 Yubin Kim , Xuhai Xu , Daniel McDuff , Cynthia Breazeal , Hae Won Park

Large language models (LLMs) have a transformative impact on a variety of scientific tasks across disciplines including biology, chemistry, medicine, and physics. However, ensuring the safety alignment of these models in scientific research…

Large Language Models (LLMs) are increasingly being integrated into various medical fields, including mental health support systems. However, there is a gap in research regarding the effectiveness of LLMs in non-English mental health…

Computation and Language · Computer Science 2026-02-10 Konstantinos Skianis , John Pavlopoulos , A. Seza Doğruöz

Clinical guidelines, typically structured as decision trees, are central to evidence-based medical practice and critical for ensuring safe and accurate diagnostic decision-making. However, it remains unclear whether Large Language Models…

Computation and Language · Computer Science 2025-05-20 Xiaomin Li , Mingye Gao , Yuexing Hao , Taoran Li , Guangya Wan , Zihan Wang , Yijun Wang

Recent strides in Large Language Models (LLMs) have saturated many Natural Language Processing (NLP) benchmarks, emphasizing the need for more challenging ones to properly assess LLM capabilities. However, domain-specific and multilingual…

The deployment of large language models (LLMs) in mental health and other sensitive domains raises urgent questions about ethical reasoning, fairness, and responsible alignment. Yet, existing benchmarks for moral and clinical…

Computation and Language · Computer Science 2025-09-16 Sai Kartheek Reddy Kasu

The mismatch between the growing demand for psychological counseling and the limited availability of services has motivated research into the application of Large Language Models (LLMs) in this domain. Consequently, there is a need for a…

Computation and Language · Computer Science 2025-11-13 Bichen Wang , Yixin Sun , Junzhe Wang , Hao Yang , Xing Fu , Yanyan Zhao , Si Wei , Shijin Wang , Bing Qin

Evaluating large language models (LLMs) for medical applications remains challenging due to benchmark saturation, limited data accessibility, and insufficient coverage of relevant tasks. Existing suites have either saturated, heavily depend…

As large language models (LLMs) are increasingly deployed in high-risk domains such as law, finance, and medicine, systematically evaluating their domain-specific safety and compliance becomes critical. While prior work has largely focused…

Computation and Language · Computer Science 2025-07-30 Zheng Hui , Yijiang River Dong , Ehsan Shareghi , Nigel Collier

The open-sourcing of large language models (LLMs) accelerates application development, innovation, and scientific progress. This includes both base models, which are pre-trained on extensive datasets without alignment, and aligned models,…

Computation and Language · Computer Science 2024-04-17 Xiao Wang , Tianze Chen , Xianjun Yang , Qi Zhang , Xun Zhao , Dahua Lin

Large language models (LLMs) have demonstrated remarkable performance on various medical benchmarks, but their capabilities across different cognitive levels remain underexplored. Inspired by Bloom's Taxonomy, we propose a…

Computation and Language · Computer Science 2025-06-11 Yuxuan Zhou , Xien Liu , Chenwei Yan , Chen Ning , Xiao Zhang , Boxun Li , Xiangling Fu , Shijin Wang , Guoping Hu , Yu Wang , Ji Wu
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