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Despite the promise of foundation models in medical AI, current systems remain limited - they are modality-specific and lack transparent reasoning processes, hindering clinical adoption. To address this gap, we present EVLF-FM, a multimodal…

Clinicians spend a significant amount of time reviewing medical images and transcribing their findings regarding patient diagnosis, referral and treatment in text form. Vision-language models (VLMs), which automatically interpret images and…

We present VisionFM, a foundation model pre-trained with 3.4 million ophthalmic images from 560,457 individuals, covering a broad range of ophthalmic diseases, modalities, imaging devices, and demography. After pre-training, VisionFM…

This study aimed to enhance disease classification accuracy from retinal fundus images by integrating fine-grained image features and global textual context using a novel multimodal deep learning architecture. Existing multimodal large…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Jason Jordan , Mohammadreza Akbari Lor , Peter Koulen , Mei-Ling Shyu , Shu-Ching Chen

In recent years, large language models (LLMs) have demonstrated remarkable potential across various medical applications. Building on this foundation, multimodal large language models (MLLMs) integrate LLMs with visual models to process…

Computation and Language · Computer Science 2025-03-11 Xiaoyi Liang , Mouxiao Bian , Moxin Chen , Lihao Liu , Junjun He , Jie Xu , Lin Li

Language-aligned vision foundation models perform strongly across diverse downstream tasks. Yet, their learned representations remain opaque, making interpreting their decision-making difficult. Recent work decompose these representations…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Kai Wittenmayer , Sukrut Rao , Amin Parchami-Araghi , Bernt Schiele , Jonas Fischer

Background: RETFound, a self-supervised, retina-specific foundation model (FM), showed potential in downstream applications. However, its comparative performance with traditional deep learning (DL) models remains incompletely understood.…

Foundation models are large-scale versatile systems trained on vast quantities of diverse data to learn generalizable representations. Their adaptability with minimal fine-tuning makes them particularly promising for medical imaging, where…

Image and Video Processing · Electrical Eng. & Systems 2025-03-20 Lucie Berger , Mathieu Lamard , Philippe Zhang , Laurent Borderie , Alexandre Le Guilcher , Pascale Massin , Béatrice Cochener , Gwenolé Quellec , Sarah Matta

Foundation models trained via vision-language pretraining have demonstrated strong zero-shot capabilities across diverse image domains, yet their application to volumetric medical imaging remains limited. We introduce MedCT-VLM: Medical CT…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Thuraya Alzubaidi , Farhad R. Nezami , Muzammil Behzad

Large language models (LLMs) have notably accelerated progress towards artificial general intelligence (AGI), with their impressive zero-shot capacity for user-tailored tasks, endowing them with immense potential across a range of…

Computer Vision and Pattern Recognition · Computer Science 2023-05-26 Wenhai Wang , Zhe Chen , Xiaokang Chen , Jiannan Wu , Xizhou Zhu , Gang Zeng , Ping Luo , Tong Lu , Jie Zhou , Yu Qiao , Jifeng Dai

Medical foundation models have shown promise in controlled benchmarks, yet widespread deployment remains hindered by reliance on task-specific fine-tuning. Here, we introduce DermFM-Zero, a dermatology vision-language foundation model…

Foundation models and vision-language pre-training have significantly advanced Vision-Language Models (VLMs), enabling multimodal processing of visual and linguistic data. However, their application in domain-specific agricultural tasks,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-23 Khang Nguyen Quoc , Phuong D. Dao , Luyl-Da Quach

Large multimodal language models (LMMs) have achieved significant success in general domains. However, due to the significant differences between medical images and text and general web content, the performance of LMMs in medical scenarios…

Computer Vision and Pattern Recognition · Computer Science 2023-06-23 Weihao Gao , Zhuo Deng , Zhiyuan Niu , Fuju Rong , Chucheng Chen , Zheng Gong , Wenze Zhang , Daimin Xiao , Fang Li , Zhenjie Cao , Zhaoyi Ma , Wenbin Wei , Lan Ma

Language-aligned vision foundation models (VFMs) enable versatile visual understanding for always-on contextual AI, but their deployment on edge devices is hindered by strict latency and power constraints. We present AdaVFM, an adaptive…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Yiwei Zhao , Yi Zheng , Huapeng Su , Jieyu Lin , Stefano Ambrogio , Cijo Jose , Michael Ramamonjisoa , Patrick Labatut , Barbara De Salvo , Chiao Liu , Phillip B. Gibbons , Ziyun Li

Vision-Language Model (VLM) have gained widespread adoption in Open-Vocabulary (OV) object detection and segmentation tasks. Despite they have shown promise on OV-related tasks, their effectiveness in conventional vision tasks has thus far…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Yongchao Feng , Yajie Liu , Shuai Yang , Wenrui Cai , Jinqing Zhang , Qiqi Zhan , Ziyue Huang , Hongxi Yan , Qiao Wan , Chenguang Liu , Junzhe Wang , Jiahui Lv , Ziqi Liu , Tengyuan Shi , Qingjie Liu , Yunhong Wang

Vision-language models (VLMs) have shown considerable potential in digital pathology, yet their effectiveness remains limited for fine-grained, disease-specific classification tasks such as distinguishing between glomerular subtypes. The…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Zhenhao Guo , Rachit Saluja , Tianyuan Yao , Quan Liu , Yuankai Huo , Benjamin Liechty , David J. Pisapia , Kenji Ikemura , Mert R. Sabuncu , Yihe Yang , Ruining Deng

Generalist vision language models (VLMs) have made significant strides in computer vision, but they fall short in specialized fields like healthcare, where expert knowledge is essential. In traditional computer vision tasks, creative or…

Recent advances in multimodal large language models enable new possibilities for image-based decision support. However, their reliability and operational trade-offs in neuroimaging remain insufficiently understood. We present a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Katarina Trojachanec Dineva , Stefan Andonov , Ilinka Ivanoska , Ivan Kitanovski , Sasho Gramatikov , Tamara Kostova , Monika Simjanoska Misheva , Kostadin Mishev

Foundation models (FMs) have shown great promise in medical image analysis by improving generalization across diverse downstream tasks. In ophthalmology, several FMs have recently emerged, but there is still no clear answer to fundamental…

There is substantial interest in developing artificial intelligence systems to support radiologists across tasks ranging from segmentation to report generation. Existing computed tomography (CT) foundation models have largely focused on…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Rubén Moreno-Aguado , Alba Magallón , Victor Moreno , Yingying Fang , Guang Yang
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