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Computational modeling of single-cell gene expression is crucial for understanding cellular processes, but generating realistic expression profiles remains a major challenge. This difficulty arises from the count nature of gene expression…

Embedding text sequences is a widespread requirement in modern language understanding. Existing approaches focus largely on constant-size representations. This is problematic, as the amount of information contained in text often varies with…

Computation and Language · Computer Science 2023-10-04 Guanghui Qin , Benjamin Van Durme

Contextual embeddings represent a new generation of semantic representations learned from Neural Language Modelling (NLM) that addresses the issue of meaning conflation hampering traditional word embeddings. In this work, we show that…

Computation and Language · Computer Science 2019-06-25 Daniel Loureiro , Alipio Jorge

We propose an unsupervised method to obtain cross-lingual embeddings without any parallel data or pre-trained word embeddings. The proposed model, which we call multilingual neural language models, takes sentences of multiple languages as…

Computation and Language · Computer Science 2018-09-10 Takashi Wada , Tomoharu Iwata

Protein language models (PLMs) encode rich biological information, yet their internal neuron representations are poorly understood. We introduce the first automated framework for labeling every neuron in a PLM with biologically grounded…

Machine Learning · Computer Science 2025-07-10 Arjun Banerjee , David Martinez , Camille Dang , Ethan Tam

Multiplex Imaging (MI) enables the simultaneous visualization of multiple biological markers in separate imaging channels at subcellular resolution, providing valuable insights into cell-type heterogeneity and spatial organization. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-11-07 Simon Gutwein , Daria Lazic , Thomas Walter , Sabine Taschner-Mandl , Roxane Licandro

Massively multilingual sentence representation models, e.g., LASER, SBERT-distill, and LaBSE, help significantly improve cross-lingual downstream tasks. However, the use of a large amount of data or inefficient model architectures results…

Computation and Language · Computer Science 2024-05-31 Zhuoyuan Mao , Chenhui Chu , Sadao Kurohashi

The increasing global prevalence of mental disorders, such as depression and PTSD, requires objective and scalable diagnostic tools. Traditional clinical assessments often face limitations in accessibility, objectivity, and consistency.…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-03 Abdelrahaman A. Hassan , Abdelrahman A. Ali , Aya E. Fouda , Radwa J. Hanafy , Mohammed E. Fouda

Understanding whether large language models (LLMs) and the human brain converge on similar computational principles remains a fundamental and important question in cognitive neuroscience and AI. Do the brain-like patterns observed in LLMs…

Computation and Language · Computer Science 2025-12-03 Yu Lei , Xingyang Ge , Yi Zhang , Yiming Yang , Bolei Ma

The current electroencephalogram (EEG) based deep learning models are typically designed for specific datasets and applications in brain-computer interaction (BCI), limiting the scale of the models and thus diminishing their perceptual…

Machine Learning · Computer Science 2024-06-06 Wei-Bang Jiang , Li-Ming Zhao , Bao-Liang Lu

This paper develops a model that addresses sentence embedding, a hot topic in current natural language processing research, using recurrent neural networks with Long Short-Term Memory (LSTM) cells. Due to its ability to capture long term…

Computation and Language · Computer Science 2016-11-18 Hamid Palangi , Li Deng , Yelong Shen , Jianfeng Gao , Xiaodong He , Jianshu Chen , Xinying Song , Rabab Ward

Electron tomography (ET) allows high-resolution reconstructions of macromolecular complexes at nearnative state. Cellular structures segmentation in the reconstruction data from electron tomographic images is often required for analyzing…

Computer Vision and Pattern Recognition · Computer Science 2018-11-29 Enze Zhang , Fa Zhang , Zhiyong Liu , Xiaohua Wan , Lifa Zhu

Contextual word embeddings obtained from pre-trained language model (PLM) have proven effective for various natural language processing tasks at the word level. However, interpreting the hidden aspects within embeddings, such as syntax and…

Computation and Language · Computer Science 2023-10-10 Nayoung Choi

Recent developments in high throughput profiling of individual neurons have spurred data driven exploration of the idea that there exist natural groupings of neurons referred to as cell types. The promise of this idea is that the immense…

Neurons and Cognition · Quantitative Biology 2019-11-14 Rohan Gala , Nathan Gouwens , Zizhen Yao , Agata Budzillo , Osnat Penn , Bosiljka Tasic , Gabe Murphy , Hongkui Zeng , Uygar Sümbül

We propose a unified optimization framework that combines neural networks with dictionary learning to model complex interactions between resting state functional MRI and behavioral data. The dictionary learning objective decomposes patient…

Machine Learning · Computer Science 2024-11-21 Niharika Shimona D'Souza , Mary Beth Nebel , Nicholas Wymbs , Stewart Mostofsky , Archana Venkataraman

The way we analyse clinical texts has undergone major changes over the last years. The introduction of language models such as BERT led to adaptations for the (bio)medical domain like PubMedBERT and ClinicalBERT. These models rely on large…

Computation and Language · Computer Science 2023-09-15 Tom van Sonsbeek , Xiantong Zhen , Marcel Worring

Recent advancements in language modeling have shown promising results when applied to time series data. In particular, fine-tuning pre-trained large language models (LLMs) for time series classification tasks has achieved state-of-the-art…

Machine Learning · Computer Science 2025-06-03 Rachneet Kaur , Zhen Zeng , Tucker Balch , Manuela Veloso

Neuron segmentation from electron microscopy (EM) volumes is crucial for understanding brain circuits, yet the complex neuronal structures in high-resolution EM images present significant challenges. EM data exhibits unique characteristics…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Yinda Chen , Haoyuan Shi , Xiaoyu Liu , Te Shi , Ruobing Zhang , Dong Liu , Zhiwei Xiong , Feng Wu

The advent of large language models (LLMs) has significantly advanced artificial intelligence (AI) in software engineering (SE), with source code embeddings playing a crucial role in tasks such as source code clone detection and source code…

Software Engineering · Computer Science 2025-06-04 Zixiang Xian , Chenhui Cui , Rubing Huang , Chunrong Fang , Zhenyu Chen

Named entity recognition (NER) models are typically based on the architecture of Bi-directional LSTM (BiLSTM). The constraints of sequential nature and the modeling of single input prevent the full utilization of global information from…

Computation and Language · Computer Science 2019-11-20 Ying Luo , Fengshun Xiao , Hai Zhao