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Large language models (LLMs) provide detailed and impressive responses to queries in English. However, are they really consistent at responding to the same query in other languages? The popular way of evaluating for multilingual performance…

Computation and Language · Computer Science 2025-05-29 Ashim Gupta , Maitrey Mehta , Zhichao Xu , Vivek Srikumar

The safe deployment of large language models (LLMs) in high-stakes fields like biomedicine, requires them to be able to reason about cause and effect. We investigate this ability by testing 13 open-source LLMs on a fundamental task:…

Computation and Language · Computer Science 2026-03-13 Sydney Anuyah , Sneha Shajee-Mohan , Ankit-Singh Chauhan , Sunandan Chakraborty

At the intersection of the rapidly growing biological data landscape and advancements in Natural Language Processing (NLP), protein language models (PLMs) have emerged as a transformative force in modern research. These models have achieved…

Biomolecules · Quantitative Biology 2025-02-12 Lei Wang , Xudong Li , Han Zhang , Jinyi Wang , Dingkang Jiang , Zhidong Xue , Yan Wang

Single-cell RNA sequencing has transformed biology by enabling the measurement of gene expression at cellular resolution, providing information for cell types, states, and disease contexts. Recently, single-cell foundation models have…

Machine Learning · Computer Science 2025-10-13 Oussama Kharouiche , Aris Markogiannakis , Xiao Fei , Michail Chatzianastasis , Michalis Vazirgiannis

The applications of large language models (LLMs) in various biological domains have been explored recently, but their reasoning ability in complex biological systems, such as pathways, remains underexplored, which is crucial for predicting…

Machine Learning · Computer Science 2025-07-23 Haiteng Zhao , Chang Ma , Fangzhi Xu , Lingpeng Kong , Zhi-Hong Deng

This paper studies the performance of large language models (LLMs), particularly regarding demographic fairness, in solving real-world healthcare tasks. We evaluate state-of-the-art LLMs with three prevalent learning frameworks across six…

Computation and Language · Computer Science 2024-12-10 Yue Zhou , Barbara Di Eugenio , Lu Cheng

In recent years, the development of Large Language Models (LLMs) has made significant breakthroughs in the field of natural language processing and has gradually been applied to the field of humanities and social sciences research. LLMs…

Computers and Society · Computer Science 2025-04-16 Peiran Gu , Fuhao Duan , Wenhao Li , Bochen Xu , Ying Cai , Teng Yao , Chenxun Zhuo , Tianming Liu , Bao Ge

Large language models (LLMs) such as ChatGPT have gained considerable interest across diverse research communities. Their notable ability for text completion and generation has inaugurated a novel paradigm for language-interfaced problem…

Quantitative Methods · Quantitative Biology 2024-02-22 Hengchuang Yin , Zhonghui Gu , Fanhao Wang , Yiparemu Abuduhaibaier , Yanqiao Zhu , Xinming Tu , Xian-Sheng Hua , Xiao Luo , Yizhou Sun

Advancements in Large Language Models (LLMs) have increased the performance of different natural language understanding as well as generation tasks. Although LLMs have breached the state-of-the-art performance in various tasks, they often…

Computation and Language · Computer Science 2025-05-28 Charaka Vinayak Kumar , Ashok Urlana , Gopichand Kanumolu , Bala Mallikarjunarao Garlapati , Pruthwik Mishra

Large language models (LLMs) like ChatGPT have shown significant advancements across diverse natural language understanding (NLU) tasks, including intelligent dialogue and autonomous agents. Yet, lacking widely acknowledged testing…

Computation and Language · Computer Science 2024-05-10 Jinyang Wu , Feihu Che , Xinxin Zheng , Shuai Zhang , Ruihan Jin , Shuai Nie , Pengpeng Shao , Jianhua Tao

Large language models (LLMs) have demonstrated impressive capabilities across diverse languages. This study explores how LLMs handle multilingualism. Based on observed language ratio shifts among layers and the relationships between network…

Computation and Language · Computer Science 2024-11-12 Yiran Zhao , Wenxuan Zhang , Guizhen Chen , Kenji Kawaguchi , Lidong Bing

Objective: To demonstrate the capabilities of Large Language Models (LLMs) as autonomous agents to reproduce findings of published research studies using the same or similar dataset. Materials and Methods: We used the "Quick Access" dataset…

Computation and Language · Computer Science 2025-06-02 Nic Dobbins , Christelle Xiong , Kristine Lan , Meliha Yetisgen

Large Language Models (LLMs) have emerged as a powerful tool in advancing the Text-to-SQL task, significantly outperforming traditional methods.Nevertheless, as a nascent research field, there is still no consensus on the optimal prompt…

Computation and Language · Computer Science 2026-03-20 Bin Zhang , Yuxiao Ye , Guoqing Du , Xiaoru Hu , Zhishuai Li , Chi Harold Liu , Zhiwei Xu , Guoliang Fan , Rui Zhao , Ziyue Li , Hangyu Mao

While large language models (LLMs) achieve near-perfect scores on medical licensing exams, these evaluations inadequately reflect the complexity and diversity of real-world clinical practice. We introduce MedHELM, an extensible evaluation…

Large Language Models (LLMs) have emerged as a transformative power in enhancing natural language comprehension, representing a significant stride toward artificial general intelligence. The application of LLMs extends beyond conventional…

Large Language Model (LLM)-based systems present new opportunities for autonomous health monitoring in sensor-rich industrial environments. This study explores the potential of LLMs to detect and classify faults directly from sensor data,…

Artificial Intelligence · Computer Science 2025-09-30 Xian Yeow Lee , Lasitha Vidyaratne , Ahmed Farahat , Chetan Gupta

Large language models (LLMs) are gaining increasing popularity in both academia and industry, owing to their unprecedented performance in various applications. As LLMs continue to play a vital role in both research and daily use, their…

Computation and Language · Computer Science 2024-01-01 Yupeng Chang , Xu Wang , Jindong Wang , Yuan Wu , Linyi Yang , Kaijie Zhu , Hao Chen , Xiaoyuan Yi , Cunxiang Wang , Yidong Wang , Wei Ye , Yue Zhang , Yi Chang , Philip S. Yu , Qiang Yang , Xing Xie

Large language models (LLMs) have shown remarkable capabilities in general domains, but their application to multi-omics biology remains underexplored. To address this gap, we introduce Biology-Instructions, the first large-scale…

Large language models (LLMs) are incredible and versatile tools for text-based tasks that have enabled countless, previously unimaginable, applications. Retrieval models, in contrast, have not yet seen such capable general-purpose models…

Information Retrieval · Computer Science 2025-09-10 Julian Killingback , Hamed Zamani
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