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The deployment of large language models (LLMs) within the healthcare sector has sparked both enthusiasm and apprehension. These models exhibit the remarkable capability to provide proficient responses to free-text queries, demonstrating a…

Computation and Language · Computer Science 2024-07-09 Zabir Al Nazi , Wei Peng

The ability to automatically generate accurate protocols for scientific experiments would represent a major step towards the automation of science. Large Language Models (LLMs) have impressive capabilities on a wide range of tasks, such as…

Computation and Language · Computer Science 2023-10-17 Odhran O'Donoghue , Aleksandar Shtedritski , John Ginger , Ralph Abboud , Ali Essa Ghareeb , Justin Booth , Samuel G Rodriques

In recent years, the rapid advancement of Large Language Models (LLMs) has transformed the landscape of scientific research, offering unprecedented support across various stages of the research cycle. This paper presents the first…

Computation and Language · Computer Science 2025-01-09 Ziming Luo , Zonglin Yang , Zexin Xu , Wei Yang , Xinya Du

Recently, the impressive performance of large language models (LLMs) on a wide range of tasks has attracted an increasing number of attempts to apply LLMs in drug discovery. However, molecule optimization, a critical task in the drug…

Quantitative Methods · Quantitative Biology 2024-01-22 Geyan Ye , Xibao Cai , Houtim Lai , Xing Wang , Junhong Huang , Longyue Wang , Wei Liu , Xiangxiang Zeng

Large language models (LLMs) demonstrate remarkable ability to comprehend, reason, and generate following nature language instructions. However, the development of LLMs has been primarily focused on high-resource languages, such as English,…

Large Language Models (LLMs) have recently demonstrated remarkable capabilities in natural language processing tasks and beyond. This success of LLMs has led to a large influx of research contributions in this direction. These works…

Computation and Language · Computer Science 2024-10-18 Humza Naveed , Asad Ullah Khan , Shi Qiu , Muhammad Saqib , Saeed Anwar , Muhammad Usman , Naveed Akhtar , Nick Barnes , Ajmal Mian

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge…

Large language models (LLMs) perform well at a myriad of tasks, but explaining the processes behind this performance is a challenge. This paper investigates whether LLMs can give faithful high-level explanations of their own internal…

Machine Learning · Computer Science 2024-05-14 Dane Sherburn , Bilal Chughtai , Owain Evans

The remarkable progress of Multi-modal Large Language Models (MLLMs) has garnered unparalleled attention, due to their superior performance in visual contexts. However, their capabilities in visual math problem-solving remain insufficiently…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Renrui Zhang , Dongzhi Jiang , Yichi Zhang , Haokun Lin , Ziyu Guo , Pengshuo Qiu , Aojun Zhou , Pan Lu , Kai-Wei Chang , Peng Gao , Hongsheng Li

The advancement of Large Language Models (LLMs) has significantly impacted biomedical Natural Language Processing (NLP), enhancing tasks such as named entity recognition, relation extraction, event extraction, and text classification. In…

Computation and Language · Computer Science 2025-03-04 Zaifu Zhan , Shuang Zhou , Huixue Zhou , Jiawen Deng , Yu Hou , Jeremy Yeung , Rui Zhang

Maps are powerful carriers of structured and contextual knowledge, encompassing geography, demographics, infrastructure, and environmental patterns. Reasoning over such knowledge requires models to integrate spatial relationships, visual…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Sharat Bhat , Harshita Khandelwal , Tushar Kataria , Vivek Gupta

Recent advances in Large Language Models (LLMs) have presented new opportunities for integrating Artificial General Intelligence (AGI) into biological research and education. This study evaluated the capabilities of leading LLMs, including…

Computation and Language · Computer Science 2023-11-15 Xinyu Gong , Jason Holmes , Yiwei Li , Zhengliang Liu , Qi Gan , Zihao Wu , Jianli Zhang , Yusong Zou , Yuxi Teng , Tian Jiang , Hongtu Zhu , Wei Liu , Tianming Liu , Yajun Yan

Research on long non-coding RNAs (lncRNAs) has garnered significant attention due to their critical roles in gene regulation and disease mechanisms. However, the complexity and diversity of lncRNA sequences, along with the limited knowledge…

Genomics · Quantitative Biology 2024-11-07 Wei Wang , Zhichao Hou , Xiaorui Liu , Xinxia Peng

From pre-trained language model (PLM) to large language model (LLM), the field of natural language processing (NLP) has witnessed steep performance gains and wide practical uses. The evaluation of a research field guides its direction of…

Computation and Language · Computer Science 2023-08-16 Ziyu Zhuang , Qiguang Chen , Longxuan Ma , Mingda Li , Yi Han , Yushan Qian , Haopeng Bai , Zixian Feng , Weinan Zhang , Ting Liu

Large Language Models (LLMs) are being employed widely to automate tasks across the software development life-cycle. It is, however, unclear whether these tasks are performed consistently with respect to the semantics of the artefacts being…

Software Engineering · Computer Science 2026-05-15 Mohammad Reza Mousavi

Speech understanding is essential for interpreting the diverse forms of information embedded in spoken language, including linguistic, paralinguistic, and non-linguistic cues that are vital for effective human-computer interaction. The…

Audio and Speech Processing · Electrical Eng. & Systems 2025-12-08 Jing Peng , Yucheng Wang , Bohan Li , Yiwei Guo , Hankun Wang , Yangui Fang , Yu Xi , Haoyu Li , Xu Li , Ke Zhang , Shuai Wang , Kai Yu

Multimodal large language models (MLLMs) have demonstrated promise on publicly available dermatology benchmarks. However, benchmark performance may not generalize to real-world dermatologic decision-making. To quantify this…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Roy Jiang , Hyunjae Kim , Zhenyue Qin , Morten Lee , Margaret MacGibeny , Ailish Hanly , Angela Sadlowski , Shanin Chowdhury , Xuguang Ai , Jeffrey Gehlhausen , Qingyu Chen

Large language models (LLMs) are increasingly explored for their reasoning capabilities, yet their ability to perform structured, constraint-based optimization from natural language remains insufficiently understood. This study evaluates…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-18 Aasish Kumar Sharma , Julian Kunkel

The rapid advancement of large language models has opened new avenues for automating complex problem-solving tasks such as algorithmic coding and competitive programming. This paper introduces a novel evaluation technique, LLM-ProS, to…

Computation and Language · Computer Science 2026-03-03 Md Sifat Hossain , Anika Tabassum , Md. Fahim Arefin , Tarannum Shaila Zaman

The rapid growth of biomedical literature poses challenges for manual knowledge curation and synthesis. Biomedical Natural Language Processing (BioNLP) automates the process. While Large Language Models (LLMs) have shown promise in general…

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