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Diffusion models have revolutionized text-to-image generation, but their real-world applications are hampered by the extensive time needed for hundreds of diffusion steps. Although progressive distillation has been proposed to speed up…

Computer Vision and Pattern Recognition · Computer Science 2023-12-01 Yifan Zhang , Bryan Hooi

Comparing images captured by disparate sensors is a common challenge in remote sensing. This requires image translation -- converting imagery from one sensor domain to another while preserving the original content. Denoising Diffusion…

Computer Vision and Pattern Recognition · Computer Science 2024-12-05 João Gabriel Vinholi , Marco Chini , Anis Amziane , Renato Machado , Danilo Silva , Patrick Matgen

In digital pathology, many image analysis tasks are challenged by the need for large and time-consuming manual data annotations to cope with various sources of variability in the image domain. Unsupervised domain adaptation based on…

Image and Video Processing · Electrical Eng. & Systems 2022-05-18 Nassim Bouteldja , Barbara Mara Klinkhammer , Tarek Schlaich , Peter Boor , Dorit Merhof

In light of the inherent entailment relations between images and text, hyperbolic point vector embeddings, leveraging the hierarchical modeling advantages of hyperbolic space, have been utilized for visual semantic representation learning.…

Artificial Intelligence · Computer Science 2024-08-21 Zhi Qiao , Linbin Han , Xiantong Zhen , Jia-Hong Gao , Zhen Qian

Histopathology serves as the gold standard in cancer diagnosis, with clinical reports being vital in interpreting and understanding this process, guiding cancer treatment and patient care. The automation of histopathology report generation…

Computer Vision and Pattern Recognition · Computer Science 2024-06-19 Zhengrui Guo , Jiabo Ma , Yingxue Xu , Yihui Wang , Liansheng Wang , Hao Chen

Histopathological analysis is a cornerstone of cancer diagnosis, with Hematoxylin and Eosin (H&E) staining routinely acquired for every patient to visualize cell morphology and tissue architecture. On the other hand, multiplex…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Guillaume Balezo , Roger Trullo , Albert Pla Planas , Etienne Decenciere , Thomas Walter

While Masked Image Modeling (MIM) has revolutionized fields of computer vision, its adoption in 3D medical image computing has been limited by the use of random masking, which overlooks the density of anatomical objects. To address this…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Jin Lee , Vu Dang , Gwang-Hyun Yu , Anh Le , Zahid Rahman , Jin-Ho Jang , Heonzoo Lee , Kun-Yung Kim , Jin-Sul Kim , Jin-Young Kim

The rapid development of digital pathology and modern deep learning has facilitated the emergence of pathology foundation models that are expected to solve general pathology problems under various disease conditions in one unified model,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-10 Yutong Sun , Sichen Zhu , Peng Qiu

In the present study, we propose a novel case-based similar image retrieval (SIR) method for hematoxylin and eosin (H&E)-stained histopathological images of malignant lymphoma. When a whole slide image (WSI) is used as an input query, it is…

Recent advances in diffusion models have significantly improved the performance of reference-guided line art colorization. However, existing methods still struggle with region-level color consistency, especially when the reference and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Qianru Qiu , Jiafeng Mao , Kento Masui , Xueting Wang

Diffusion-based watermarking methods embed verifiable marks by manipulating the initial noise or the reverse diffusion trajectory. However, these methods share a critical assumption: verification can succeed only if the diffusion trajectory…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Rui Bao , Zheng Gao , Xiaoyu Li , Xiaoyan Feng , Yang Song , Jiaojiao Jiang

Creating ultra-high-resolution spatially varying bidirectional reflectance functions (SVBRDFs) is critical for photorealistic 3D content creation, to faithfully represent fine-scale surface details required for close-up rendering. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Zixiong Wang , Jian Yang , Yiwei Hu , Milos Hasan , Beibei Wang

Low-dose CT (LDCT) protocols reduce radiation exposure but increase image noise, compromising diagnostic confidence. Diffusion-based generative models have shown promise for LDCT denoising by learning image priors and performing iterative…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Tomás de la Sotta , José M. Saavedra , Héctor Henríquez , Violeta Chang , Aline Xavier

While multiplex immunofluorescence (mIF) imaging provides deep, spatially-resolved molecular data, integrating this information with the morphological standard of Hematoxylin & Eosin (H&E) can be very important for obtaining complementary…

Quantitative Methods · Quantitative Biology 2025-08-08 Jillur Rahman Saurav , Mohammad Sadegh Nasr , Jacob M. Luber

Multiplex immunofluorescence (mIF) enables simultaneous single-cell quantification of multiple biomarkers within intact tissue architecture, yet its high reagent cost, multi-round staining protocols, and need for specialized imaging…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Junhyeok Lee , Han Jang , Heeseong Eum , Joon Jang , Kyu Sung Choi

Spatial transcriptomics (ST) enables the visualization of gene expression within the context of tissue morphology. This emerging discipline has the potential to serve as a foundation for developing tools to design precision medicines.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-12 Shivam Kumar , Samrat Chatterjee

Medical practitioners use a number of diagnostic tests to make a reliable diagnosis. Traditionally, Haematoxylin and Eosin (H&E) stained glass slides have been used for cancer diagnosis and tumor detection. However, recently a variety of…

Image and Video Processing · Electrical Eng. & Systems 2023-12-27 Abubakr Shafique , Morteza Babaie , Ricardo Gonzalez , H. R. Tizhoosh

Stains are essential in histopathology to visualize specific tissue characteristics, with Haematoxylin and Eosin (H&E) serving as the clinical standard. However, pathologists frequently utilize a variety of special stains for the diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Oskar Thaeter , Christian Grashei , Anette Haas , Elisa Schmoeckel , Han Li , Peter J. Schüffler

Metastatic Progression remains the leading cause of cancer-related mortality, yet predicting whether a primary tumor will metastasize and where it will disseminate directly from histopathology remains a fundamental challenge. Although…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Yixin Chen , Ziyu Su , Lingbin Meng , Elshad Hasanov , Wei Chen , Anil Parwani , M. Khalid Khan Niazi

Deep learning-based virtual staining was developed to introduce image contrast to label-free tissue sections, digitally matching the histological staining, which is time-consuming, labor-intensive, and destructive to tissue. Standard…

Image and Video Processing · Electrical Eng. & Systems 2022-10-31 Yijie Zhang , Luzhe Huang , Tairan Liu , Keyi Cheng , Kevin de Haan , Yuzhu Li , Bijie Bai , Aydogan Ozcan