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Diffusion-based generative models have shown promise in synthesizing histopathology images to address data scarcity caused by privacy constraints. Diagnostic text reports provide high-level semantic descriptions, and masks offer…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Mahesh Bhosale , Abdul Wasi , Yuanhao Zhai , Yunjie Tian , Samuel Border , Nan Xi , Pinaki Sarder , Junsong Yuan , David Doermann , Xuan Gong

Spatial Transcriptomics (ST) merges the benefits of pathology images and gene expression, linking molecular profiles with tissue structure to analyze spot-level function comprehensively. Predicting gene expression from histology images is a…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Chen Zhang , Yilu An , Ying Chen , Hao Li , Xitong Ling , Lihao Liu , Junjun He , Yuxiang Lin , Zihui Wang , Rongshan Yu

Accurate gland segmentation in histopathology images is essential for cancer diagnosis and prognosis. However, significant variability in Hematoxylin and Eosin (H&E) staining and tissue morphology, combined with limited annotated data,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Ha-Hieu Pham , Nguyen Lan Vi Vu , Thanh-Huy Nguyen , Ulas Bagci , Min Xu , Trung-Nghia Le , Huy-Hieu Pham

Controllable human image generation (HIG) has numerous real-life applications. State-of-the-art solutions, such as ControlNet and T2I-Adapter, introduce an additional learnable branch on top of the frozen pre-trained stable diffusion (SD)…

Computer Vision and Pattern Recognition · Computer Science 2023-04-11 Xuan Ju , Ailing Zeng , Chenchen Zhao , Jianan Wang , Lei Zhang , Qiang Xu

Deep learning has been effective for histology image analysis in digital pathology. However, many current deep learning approaches require large, strongly- or weakly-labeled images and regions of interest, which can be time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2023-04-07 Joseph DiPalma , Lorenzo Torresani , Saeed Hassanpour

Color inconsistency is an inevitable challenge in computational pathology, which generally happens because of stain intensity variations or sections scanned by different scanners. It harms the pathological image analysis methods, especially…

Image and Video Processing · Electrical Eng. & Systems 2022-03-01 Bingchao Zhao , Jiatai Lin , Changhong Liang , Zongjian Yi , Xin Chen , Bingbing Li , Weihao Qiu , Danyi Li , Li Liang , Chu Han , Zaiyi Liu

Out-of-distribution (OOD) detection is crucial for the safety and reliability of artificial intelligence algorithms, especially in the medical domain. In the context of the Medical OOD (MOOD) detection challenge 2023, we propose a pipeline…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 Evi M. C. Huijben , Sina Amirrajab , Josien P. W. Pluim

Advancement in digital pathology and artificial intelligence has enabled deep learning-based computer vision techniques for automated disease diagnosis and prognosis. However, WSIs present unique computational and algorithmic challenges.…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Yash Sharma , Lubaina Ehsan , Sana Syed , Donald E. Brown

Histopathology, the current gold standard for cancer diagnosis, involves the manual examination of tissue samples after chemical staining, a time-consuming process requiring expert analysis. Raman spectroscopy is an alternative, stain-free…

This thesis focuses on the research and development of the Hemodynamic Tissue Signature (HTS) method: an unsupervised machine learning approach to describe the vascular heterogeneity of glioblastomas by means of perfusion MRI analysis. The…

Computer Vision and Pattern Recognition · Computer Science 2020-09-15 Javier Juan-Albarracín

In this manuscript, we present a novel approach for sampling from a continuous multivariate probability distribution, which may either be explicitly known (up to a normalization factor) or represented via empirical samples. Our method…

Machine Learning · Statistics 2025-03-14 Hamidreza Behjoo , Michael Chertkov

Incomplete data are common in real-world tabular applications, where numerical, categorical, and discrete attributes coexist within a single dataset. This heterogeneous structure presents significant challenges for existing diffusion-based…

Machine Learning · Computer Science 2025-11-19 Youran Zhou , Mohamed Reda Bouadjenek , Sunil Aryal

Hematoxylin and Eosin (H&E) staining of whole slide images (WSIs) is considered the gold standard for pathologists and medical practitioners for tumor diagnosis, surgical planning, and post-operative assessment. With the rapid advancement…

Computer Vision and Pattern Recognition · Computer Science 2024-11-08 Liangrui Pan , Mao Huang , Lian Wang , Pinle Qin , Shaoliang Peng

Diffusion-based Image Editing (DIE) is an emerging research hot-spot, which often applies a semantic mask to control the target area for diffusion-based editing. However, most existing solutions obtain these masks via manual operations or…

Computer Vision and Pattern Recognition · Computer Science 2024-01-24 Siyu Zou , Jiji Tang , Yiyi Zhou , Jing He , Chaoyi Zhao , Rongsheng Zhang , Zhipeng Hu , Xiaoshuai Sun

Immunohistochemistry (IHC) provides information on protein expression in tissue sections and is commonly used to support pathology diagnosis and disease triage. While AI models for H\&E-stained slides show promise, their applicability to…

Recent methods exploit the powerful text-to-image (T2I) diffusion models for real-world image super-resolution (Real-ISR) and achieve impressive results compared to previous models. However, we observe two kinds of inconsistencies in…

Computer Vision and Pattern Recognition · Computer Science 2025-04-28 Junhao Gu , Peng-Tao Jiang , Hao Zhang , Mi Zhou , Jinwei Chen , Wenming Yang , Bo Li

Histopathology whole slide images (WSIs) can reveal significant inter-hospital variability such as illumination, color or optical artifacts. These variations, caused by the use of different scanning protocols across medical centers…

Computer Vision and Pattern Recognition · Computer Science 2022-07-01 Marin Scalbert , Maria Vakalopoulou , Florent Couzinié-Devy

Diffusion models have recently received a surge of interest due to their impressive performance for image restoration, especially in terms of noise robustness. However, existing diffusion-based methods are trained on a large amount of…

Computer Vision and Pattern Recognition · Computer Science 2023-03-21 Yuchun Miao , Lefei Zhang , Liangpei Zhang , Dacheng Tao

State-of-the-art Style Transfer methods often leverage pre-trained encoders optimized for discriminative tasks, which may not be ideal for image synthesis. This can result in significant artifacts and loss of photorealism. Motivated by the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-04 Renan A. Rojas-Gomez , Minh N. Do

Positron emission tomography (PET) is a widely recognized technique for diagnosing neurodegenerative diseases, offering critical functional insights. However, its high costs and radiation exposure hinder its widespread use. In contrast,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Yitong Li , Igor Yakushev , Dennis M. Hedderich , Christian Wachinger
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