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Segment Anything Model (SAM) demonstrates powerful zero-shot capabilities; however, its accuracy and robustness significantly decrease when applied to medical image segmentation. Existing methods address this issue through modality fusion,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Yiheng Zhong , Zihong Luo , Chengzhi Liu , Feilong Tang , Zelin Peng , Ming Hu , Yingzhen Hu , Jionglong Su , Zongyuan Ge , Imran Razzak

Medical image segmentation is a fundamental and critical step in many image-guided clinical approaches. Recent success of deep learning-based segmentation methods usually relies on a large amount of labeled data, which is particularly…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Rushi Jiao , Yichi Zhang , Le Ding , Rong Cai , Jicong Zhang

Segmentation of organs or lesions from medical images plays an essential role in many clinical applications such as diagnosis and treatment planning. Though Convolutional Neural Networks (CNN) have achieved the state-of-the-art performance…

Computer Vision and Pattern Recognition · Computer Science 2021-05-27 Xiangde Luo , Guotai Wang , Tao Song , Jingyang Zhang , Michael Aertsen , Jan Deprest , Sebastien Ourselin , Tom Vercauteren , Shaoting Zhang

Recently, Segment Anything Model (SAM) has demonstrated strong generalizability in various instance segmentation tasks. However, its performance is severely dependent on the quality of manual prompts. In addition, the RGB images that…

Computer Vision and Pattern Recognition · Computer Science 2026-02-09 Yihan Shang , Wei Wang , Chao Huang , Xinghui Dong

The Segment Anything Model (SAM) has achieved remarkable successes in the realm of natural image segmentation, but its deployment in the medical imaging sphere has encountered challenges. Specifically, the model struggles with medical…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Shreyank N Gowda , David A. Clifton

Diffusion models have shown impressive performance for generative modelling of images. In this paper, we present a novel semantic segmentation method based on diffusion models. By modifying the training and sampling scheme, we show that…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Julia Wolleb , Robin Sandkühler , Florentin Bieder , Philippe Valmaggia , Philippe C. Cattin

Semantic segmentations of pathological entities have crucial clinical value in computational pathology workflows. Foundation models, such as the Segment Anything Model (SAM), have been recently proposed for universal use in segmentation…

Image and Video Processing · Electrical Eng. & Systems 2023-07-20 Jingwei Zhang , Ke Ma , Saarthak Kapse , Joel Saltz , Maria Vakalopoulou , Prateek Prasanna , Dimitris Samaras

Medical image segmentation is an important analysis task in clinical practice and research. Deep learning has massively advanced the field, but current approaches are mostly based on models trained for a specific task. Training such models…

Image and Video Processing · Electrical Eng. & Systems 2025-12-18 Anwai Archit , Luca Freckmann , Constantin Pape

Medical image segmentation is crucial for clinical diagnosis and treatment planning. Traditional methods typically produce a single segmentation mask, failing to capture inherent uncertainty. Recent generative models enable the creation of…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Huynh Trinh Ngoc , Toan Nguyen Hai , Ba Luong Son , Long Tran Quoc

Automatic fetal brain tissue segmentation can enhance the quantitative assessment of brain development at this critical stage. Deep learning methods represent the state of the art in medical image segmentation and have also achieved…

Image and Video Processing · Electrical Eng. & Systems 2023-01-05 Davood Karimi , Caitlin K. Rollins , Clemente Velasco-Annis , Abdelhakim Ouaalam , Ali Gholipour

We propose a segmentation framework that uses deep neural networks and introduce two innovations. First, we describe a biophysics-based domain adaptation method. Second, we propose an automatic method to segment white and gray matter, and…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Amir Gholami , Shashank Subramanian , Varun Shenoy , Naveen Himthani , Xiangyu Yue , Sicheng Zhao , Peter Jin , George Biros , Kurt Keutzer

The successful adaptation of foundation models to multi-modal medical imaging is a critical yet unresolved challenge. Existing models often struggle to effectively fuse information from multiple sources and adapt to the heterogeneous nature…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Shadi Alijani , Fereshteh Aghaee Meibodi , Homayoun Najjaran

Due to the inherent flexibility of prompting, foundation models have emerged as the predominant force in the fields of natural language processing and computer vision. The recent introduction of the Segment Anything Model (SAM) signifies a…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Yichi Zhang , Zhenrong Shen , Rushi Jiao

Medical image segmentation is evolving from task-specific models toward generalizable frameworks. Recent research leverages Multi-modal Large Language Models (MLLMs) as autonomous agents, employing reinforcement learning with verifiable…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Shengyuan Liu , Liuxin Bao , Qi Yang , Wanting Geng , Boyun Zheng , Chenxin Li , Wenting Chen , Houwen Peng , Yixuan Yuan

Brain lesion segmentation from multi-modal MRI often assumes fixed modality sets or predefined pathologies, making existing models difficult to adapt across cohorts and imaging protocols. Continual learning (CL) offers a natural solution…

Image and Video Processing · Electrical Eng. & Systems 2026-01-21 Yousef Sadegheih , Dorit Merhof , Pratibha Kumari

Despite significant progress in pixel-level medical image analysis, existing medical image segmentation models rarely explore medical segmentation and diagnosis tasks jointly. However, it is crucial for patients that models can provide…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Lingran Song , Yucheng Zhou , Jianbing Shen

In digital pathology, precise nuclei segmentation is pivotal yet challenged by the diversity of tissue types, staining protocols, and imaging conditions. Recently, the segment anything model (SAM) revealed overwhelming performance in…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Zhen Chen , Qing Xu , Xinyu Liu , Yixuan Yuan

Deep learning methods are actively used for brain lesion segmentation. One of the most popular models is DeepMedic, which was developed for segmentation of relatively large lesions like glioma and ischemic stroke. In our work, we consider…

Computer Vision and Pattern Recognition · Computer Science 2018-08-02 Egor Krivov , Valery Kostjuchenko , Alexandra Dalechina , Boris Shirokikh , Gleb karchuk , Alexander Denisenko , Andrey Golanov , Mikhail Belyaev

In this paper, we present an automated approach for segmenting multiple sclerosis (MS) lesions from multi-modal brain magnetic resonance images. Our method is based on a deep end-to-end 2D convolutional neural network (CNN) for slice-based…

Computer Vision and Pattern Recognition · Computer Science 2019-04-09 Shahab Aslani , Michael Dayan , Loredana Storelli , Massimo Filippi , Vittorio Murino , Maria A Rocca , Diego Sona

Medical imaging plays a critical role in the diagnosis and treatment planning of various medical conditions, with radiology and pathology heavily reliant on precise image segmentation. The Segment Anything Model (SAM) has emerged as a…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Amin Ranem , Niklas Babendererde , Moritz Fuchs , Anirban Mukhopadhyay