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Medical image segmentation has advanced rapidly over the past two decades, largely driven by deep learning, which has enabled accurate and efficient delineation of cells, tissues, organs, and pathologies across diverse imaging modalities.…

Image and Video Processing · Electrical Eng. & Systems 2025-08-29 Guoping Xu , Jayaram K. Udupa , Jax Luo , Songlin Zhao , Yajun Yu , Scott B. Raymond , Hao Peng , Lipeng Ning , Yogesh Rathi , Wei Liu , You Zhang

The identification and segmentation of moderate-severe traumatic brain injury (TBI) lesions pose a significant challenge in neuroimaging. This difficulty arises from the extreme heterogeneity of these lesions, which vary in size, number,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Ghanshyam Dhamat , Vaanathi Sundaresan

Deep neural networks have demonstrated exceptional efficacy in stroke lesion segmentation. However, the delineation of small lesions, critical for stroke diagnosis, remains a challenge. In this study, we propose two straightforward yet…

Computer Vision and Pattern Recognition · Computer Science 2024-08-07 Liang Shang , Zhengyang Lou , Andrew L. Alexander , Vivek Prabhakaran , William A. Sethares , Veena A. Nair , Nagesh Adluru

Medical image segmentation is a challenging task with inherent ambiguity and high uncertainty, attributed to factors such as unclear tumor boundaries and multiple plausible annotations. The accuracy and diversity of segmentation masks are…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Tao Chen , Chenhui Wang , Hongming Shan

The Segment Anything Model (SAM) and CLIP are remarkable vision foundation models (VFMs). SAM, a prompt driven segmentation model, excels in segmentation tasks across diverse domains, while CLIP is renowned for its zero shot recognition…

Computer Vision and Pattern Recognition · Computer Science 2024-05-01 Sidra Aleem , Fangyijie Wang , Mayug Maniparambil , Eric Arazo , Julia Dietlmeier , Guenole Silvestre , Kathleen Curran , Noel E. O'Connor , Suzanne Little

Medical image segmentation is vital for clinical diagnosis and quantitative analysis, yet remains challenging due to the heterogeneity of imaging modalities and the high cost of pixel-level annotations. Although general interactive…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Yujie Lu , Jingwen Li , Sibo Ju , Yanzhou Su , he yao , Yisong Liu , Min Zhu , Junlong Cheng

Accurate segmentation of polyps and skin lesions is essential for diagnosing colorectal and skin cancers. While various segmentation methods for polyps and skin lesions using fully supervised deep learning techniques have been developed,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-03 Encheng Su , Hu Cao , Alois Knoll

Image segmentation is a long-standing challenge in computer vision, studied continuously over several decades, as evidenced by seminal algorithms such as N-Cut, FCN, and MaskFormer. With the advent of foundation models (FMs), contemporary…

Computer Vision and Pattern Recognition · Computer Science 2024-11-28 Tianfei Zhou , Wang Xia , Fei Zhang , Boyu Chang , Wenguan Wang , Ye Yuan , Ender Konukoglu , Daniel Cremers

Magnetic resonance (MR) protocols rely on several sequences to assess pathology and organ status properly. Despite advances in image analysis, we tend to treat each sequence, here termed modality, in isolation. Taking advantage of the…

Computer Vision and Pattern Recognition · Computer Science 2020-11-11 Agisilaos Chartsias , Giorgos Papanastasiou , Chengjia Wang , Scott Semple , David E. Newby , Rohan Dharmakumar , Sotirios A. Tsaftaris

Image analysis using more than one modality (i.e. multi-modal) has been increasingly applied in the field of biomedical imaging. One of the challenges in performing the multimodal analysis is that there exist multiple schemes for fusing the…

Computer Vision and Pattern Recognition · Computer Science 2018-06-19 Zhe Guo , Xiang Li , Heng Huang , Ning Guo , Quanzheng Li

Masked image modeling (MIM) with transformer backbones has recently been exploited as a powerful self-supervised pre-training technique. The existing MIM methods adopt the strategy to mask random patches of the image and reconstruct the…

Computer Vision and Pattern Recognition · Computer Science 2024-02-05 Zhaohu Xing , Lei Zhu , Lequan Yu , Zhiheng Xing , Liang Wan

The goal of interactive image segmentation is to delineate specific regions within an image via visual or language prompts. Low-latency and high-quality interactive segmentation with diverse prompts remain challenging for existing…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Qin Liu , Jaemin Cho , Mohit Bansal , Marc Niethammer

Modern segmentation models achieve strong predictive performance but remain largely opaque, limiting our ability to diagnose failures, understand dataset shift, or intervene in a principled manner. We introduce Med-SegLens, a model-diffing…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Salma J. Ahmed , Emad A. Mohammed , Azam Asilian Bidgoli

Accurate segmentation of tubular structures in medical images, such as vessels and airway trees, is crucial for computer-aided diagnosis, radiotherapy, and surgical planning. However, significant challenges exist in algorithm design when…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Yi Huang , Ke Zhang , Wei Liu , Yuanyuan Wang , Vishal M. Patel , Le Lu , Xu Han , Dakai Jin , Ke Yan

The performance of medical image segmentation is increasingly defined by the efficiency of data utilization rather than merely the volume of raw data. Accurate segmentation, particularly for complex pathologies like meningiomas, demands…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Yunhao Xu , Fuquan Zong , Yexuan Xing , Chulong Zhang , Guang Yang , Shilong Yang , Xiaokun Liang , Juan Yu

The recently released Segment Anything Model (SAM) has shown powerful zero-shot segmentation capabilities through a semi-automatic annotation setup in which the user can provide a prompt in the form of clicks or bounding boxes. There is…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Benjamin Towle , Xin Chen , Ke Zhou

This study addresses critical gaps in automated lymphoma segmentation from PET/CT images, focusing on issues often overlooked in existing literature. While deep learning has been applied for lymphoma lesion segmentation, few studies…

Medical image segmentation of anatomical structures and pathology is crucial in modern clinical diagnosis, disease study, and treatment planning. To date, great progress has been made in deep learning-based segmentation techniques, but most…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 Taha Koleilat , Hojat Asgariandehkordi , Hassan Rivaz , Yiming Xiao

Segment Anything Model (SAM) has demonstrated impressive zero-shot performance and brought a range of unexplored capabilities to natural image segmentation tasks. However, as a very important branch of image segmentation, the performance of…

Computer Vision and Pattern Recognition · Computer Science 2025-02-04 Bin Xie , Hao Tang , Dawen Cai , Yan Yan , Gady Agam

Blood vessels of the brain provide the human brain with the required nutrients and oxygen. As a vulnerable part of the cerebral blood supply, pathology of small vessels can cause serious problems such as Cerebral Small Vessel Diseases…

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