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Dynamic programming (DP) is a cornerstone of combinatorial optimization, yet its inherently sequential structure has long limited its scalability in scenario-based stochastic programming (SP). This paper introduces a GPU-accelerated…

Optimization and Control · Mathematics 2025-11-25 Jingyi Zhao , Linxin Yang , Haohua Zhang , Tian Ding

Spiking neural networks (SNNs), recognized as an energy-efficient alternative to traditional artificial neural networks (ANNs), have advanced rapidly through the scaling of models and datasets. However, such scaling incurs considerable…

Neural and Evolutionary Computing · Computer Science 2025-10-07 Chenxiang Ma , Xinyi Chen , Yujie Wu , Kay Chen Tan , Jibin Wu

In this work, we propose FastDPM, a unified framework for fast sampling in diffusion probabilistic models. FastDPM generalizes previous methods and gives rise to new algorithms with improved sample quality. We systematically investigate the…

Machine Learning · Computer Science 2021-06-25 Zhifeng Kong , Wei Ping

We present a scalable dissipative particle dynamics simulation code, fully implemented on the Graphics Processing Units (GPUs) using a hybrid CUDA/MPI programming model, which achieves 10-30 times speedup on a single GPU over 16 CPU cores…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-12-01 Yu-Hang Tang , George Em Karniadakis

Sequence alignment data is often ordered by coordinate (id of the reference sequence plus position on the sequence where the fragment was mapped) when stored in BAM files, as this simplifies the extraction of variants between the mapped…

Genomics · Quantitative Biology 2014-06-24 German Tischler , Steven Leonard

Reasoning models excel by generating long chain-of-thoughts, but decoding the resulting thousands of tokens is slow. Token-level speculative decoding (SD) helps, but its benefit is capped, because the chance that an entire $\gamma$-token…

Machine Learning · Computer Science 2025-06-25 Yichao Fu , Rui Ge , Zelei Shao , Zhijie Deng , Hao Zhang

Packet classification is a vital and complicated task as the processing of packets should be done at a specified line speed. In order to classify a packet as belonging to a particular flow or set of flows, network nodes must perform a…

Networking and Internet Architecture · Computer Science 2014-04-08 Pallavi. V. S , Dr. Rukmani Devi. D

Graph Neural Networks (GNNs) have shown great superiority on non-Euclidean graph data, achieving ground-breaking performance on various graph-related tasks. As a practical solution to train GNN on large graphs with billions of nodes and…

Machine Learning · Computer Science 2024-09-24 Zeyu Zhu , Peisong Wang , Qinghao Hu , Gang Li , Xiaoyao Liang , Jian Cheng

Diffusion models have achieved remarkable success in generating high-fidelity content but suffer from slow, iterative sampling, resulting in high latency that limits their use in interactive applications. We introduce DRiffusion, a parallel…

Machine Learning · Computer Science 2026-03-30 Runsheng Bai , Chengyu Zhang , Yangdong Deng

Active learning is an important technique for low-resource sequence labeling tasks. However, current active sequence labeling methods use the queried samples alone in each iteration, which is an inefficient way of leveraging human…

Computation and Language · Computer Science 2020-10-07 Rongzhi Zhang , Yue Yu , Chao Zhang

This paper presents an underlying framework for both automating and accelerating malware classification, more specifically, mapping malicious executables to known Advanced Persistent Threat (APT) groups. The main feature of this analysis is…

Cryptography and Security · Computer Science 2025-04-23 Noah Subedar , Taeui Kim , Saathwick Venkataramalingam

Speculative decoding has proven to be an efficient solution to large language model (LLM) inference, where the small drafter predicts future tokens at a low cost, and the target model is leveraged to verify them in parallel. However, most…

Computation and Language · Computer Science 2024-10-10 Zilin Xiao , Hongming Zhang , Tao Ge , Siru Ouyang , Vicente Ordonez , Dong Yu

This paper introduces a high-throughput software tool framework called {\it sam2bam} that enables users to significantly speedup pre-processing for next-generation sequencing data. The sam2bam is especially efficient on single-node…

Genomics · Quantitative Biology 2017-02-08 Takeshi Ogasawara , Yinhe Cheng , Tzy-Hwa Kathy Tzeng

Recent advances in reasoning models have demonstrated significant improvements in accuracy by employing detailed and comprehensive reasoning processes. However, generating these lengthy reasoning sequences is computationally expensive and…

Computation and Language · Computer Science 2025-08-27 Yijiong Yu

At the last step of short read mapping, the candidate locations of the reads on the reference genome are verified to compute their differences from the corresponding reference segments using sequence alignment algorithms. Calculating the…

Genomics · Quantitative Biology 2024-07-04 Zülal Bingöl , Mohammed Alser , Onur Mutlu , Ozcan Ozturk , Can Alkan

Predicting the binding structure of a small molecule ligand to a protein -- a task known as molecular docking -- is critical to drug design. Recent deep learning methods that treat docking as a regression problem have decreased runtime…

Biomolecules · Quantitative Biology 2023-02-14 Gabriele Corso , Hannes Stärk , Bowen Jing , Regina Barzilay , Tommi Jaakkola

With the advent of Next-Generation (NG) sequencing, it has become possible to sequence an entire genome quickly and inexpensively. However, in some experiments one only needs to extract and assembly a portion of the sequence reads, for…

Genomics · Quantitative Biology 2013-08-01 Ilya Y. Zhbannikov , Samuel S. Hunter , Matthew L. Settles , James A. Foster

Change point analysis is concerned with detecting and locating structure breaks in the underlying model of a sequence of observations ordered by time, space or other variables. A widely adopted approach for change point analysis is to…

Methodology · Statistics 2024-04-10 Xingchi Li , Xianyang Zhang

Finding the best K-sparse approximation of a signal in a redundant dictionary is an NP-hard problem. Suboptimal greedy matching pursuit (MP) algorithms are generally used for this task. In this work, we present an acceleration technique and…

Numerical Analysis · Mathematics 2022-02-28 Zdeněk Průša , Nicki Holighaus , Peter Balazs

Data preprocessing is a crucial step in the machine learning process that transforms raw data into a more usable format for downstream ML models. However, it can be costly and time-consuming, often requiring the expertise of domain experts.…

Databases · Computer Science 2023-08-23 Peng Li , Zhiyi Chen , Xu Chu , Kexin Rong