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Mid-infrared (MIR) spectroscopy is widely recognized as a powerful, non-distractive method for chemical analysis. However, its utility is constrained by a micrometer-scale spatial resolution imposed by the long-wavelength MIR diffraction…

Quantum imaging with undetected photons (QIUP) has recently emerged as a new powerful imaging tool. Exploiting the spatial entanglement of photon pairs, it allows decoupling of the sensing and detection wavelengths, facilitating imaging in…

Quantum Physics · Physics 2022-02-23 Inna Kviatkovsky , Helen M. Chrzanowski , Sven Ramelow

Mid-infrared (MIR) imaging offers powerful capabilities for label-free chemical analysis, yet its practical deployment remains hindered by the high cost and cryogenic complexity of conventional cameras. Two-photon absorption (TPA) provides…

Optics · Physics 2026-05-25 Huijie Ma , Kun Huang , Jianan Fang , Ziyu He , Yan Liang , Heping Zeng

Sensing with undetected photons has enabled new, unconventional approaches to Fourier transform infrared (FTIR) spectroscopy. Leveraging properties of non-degenerated entangled photon pairs, mid-IR information can be accessed in the near-IR…

Quantum imaging with undetected light (QIUL) can retrieve amplitude and phase information of an object by exploiting the quantum correlations of photon-pairs generated through spontaneous parametric down conversion (SPDC), where the…

Owing to its capacity for unique (bio)-chemical specificity, microscopy withmid-IR illumination holds tremendous promise for a wide range of biomedical and industrial applications. The primary limitation, however, remains detection; with…

Numerous molecules exhibit unique absorption bands in the fingerprint infrared (IR) region, allowing chemical identification and detection. This makes IR spectroscopy an essential tool in biomedical diagnostics, sensing, and material…

Optics · Physics 2022-02-04 Anna V. Paterova , Zi S. D. Toa , Hongzhi Yang , Leonid A. Krivitsky

Pinhole imaging is the most primitive and simplest lensless imaging paradigm, capable of transcending the physical limitations of conventional lens optics. This modality is particularly attractive for accessing a virtually infinite depth of…

Optics · Physics 2026-05-25 Yanan Li , Kun Huang , Jianan Fang , Zhuohang Wei , Heping Zeng

Spectral imaging in the mid-infrared (MIR) range provides simultaneous morphological and chemical information of a wide variety of samples. However, current MIR technologies struggle to produce high-definition images over a broad spectral…

Hyperspectral imaging in the mid-infrared (MIR) spectral range provides unique molecular specificity by probing fundamental vibrational modes of molecular bonds, making it highly valuable for biomedical and biochemical applications.…

Room temperature detection of molecular vibrations in the mid-infrared (MIR, $\lambda$ =3-30$\mu$m) has numerous applications including real-time gas sensing, chemical reactivity, medical imaging, astronomical surveys, and quantum…

Applied Physics · Physics 2022-05-17 Rohit Chikkaraddy , Rakesh Arul , Lukas A. Jakob , Jeremy J. Baumberg

Mid-infrared (mid-IR) spectroscopy offers unparalleled opportunities in sensing through chemically specific detection of molecular absorption fingerprints. Yet, its practical applications are limited by the weak light-matter interaction in…

Sensing with undetected photons has become a vibrant, application-driven research domain with a special focus on the mid-infrared (mid-IR) wavelength region. Since the mid-IR contains spectral bands with highly specific and strong molecular…

Infrared (IR) imaging is one of the significant tools for the quality control measurements of fabricated samples. Standard IR imaging techniques use direct measurements, where light sources and detectors operate at IR range. Due to the…

Quantum Physics · Physics 2020-09-01 Anna V. Paterova , Hongzhi Yang , Zi S. D. Toa , Leonid A. Krivitsky

Quantum imaging with undetected photons (QIUP) is an emerging technique that decouples the processes of illuminating an object and projecting its image. The properties of the illuminating and detected light can thus be simultaneously…

We investigate quantum spectroscopy with undetected photons for protein detection in the mid-infrared spectral region. Classical Fourier-transform infrared spectroscopy of protein samples (bovine serum albumin and N-terminal pro-brain…

Mid-infrared (mid-IR) spectroscopy is a crucial workhorse for a plethora of analytical applications and is suitable for diverse materials, including gases, polymers or biological tissue. However, this technologically significant wavelength…

Optics · Physics 2022-02-23 Paul Kaufmann , Helen M. Chrzanowski , Aron Vanselow , Sven Ramelow

Harnessing the quantum interference of photon-pair generation processes, infrared quantum absorption spectroscopy (IRQAS) can extract the infrared optical properties of a sample through visible or near-infrared photon detection without the…

Optics · Physics 2022-06-22 Yu Mukai , Ryo Okamoto , Shigeki Takeuchi

We present a system for molecular spectroscopy using a broadband mid-infrared laser with near infrared detection. Difference frequency generation of a Yb:fiber femtosecond laser produced a mid-infrared (MIR) source tunable from 2100-3700…

Optics · Physics 2015-05-30 Todd A. Johnson , Scott A. Diddams

Fourier-transform infrared spectroscopy (FTIR) is an indispensable analytical method that allows label-free identification of substances via fundamental molecular vibrations. However, the sensitivity of FTIR is often limited by the low…

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