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Electroencephalography (EEG) is establishing itself as an important, low-cost, noninvasive diagnostic tool for the early detection of Parkinson's Disease (PD). In this context, EEG-based Deep Learning (DL) models have shown promising…

Conventionally, AI models are thought to trade off explainability for lower accuracy. We develop a training strategy that not only leads to a more explainable AI system for object classification, but as a consequence, suffers no perceptible…

Computer Vision and Pattern Recognition · Computer Science 2020-03-17 Andrea Zunino , Sarah Adel Bargal , Riccardo Volpi , Mehrnoosh Sameki , Jianming Zhang , Stan Sclaroff , Vittorio Murino , Kate Saenko

Parkinson's disease (PD) is a progressive neurodegenerative disorder that, in addition to directly impairing functional mobility, is frequently associated with vocal impairments such as hypophonia and dysarthria, which typically manifest in…

Information from neuroimaging examinations is increasingly used to support diagnoses of dementia, e.g., Alzheimer's disease. While current clinical practice is mainly based on visual inspection and feature engineering, Deep Learning…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Lisa Anita De Santi , Jörg Schlötterer , Michael Scheschenja , Joel Wessendorf , Meike Nauta , Vincenzo Positano , Christin Seifert

Background: Parkinson's disease (PD) is a prevalent long-term neurodegenerative disease. Though the diagnostic criteria of PD are relatively well defined, the current medical imaging diagnostic procedures are expertise-demanding, and thus…

Quantitative Methods · Quantitative Biology 2019-02-27 Jiahang Xu , Fangyang Jiao , Yechong Huang , Xinzhe Luo , Qian Xu , Ling Li , Xueling Liu , Chuantao Zuo , Ping Wu , Xiahai Zhuang

Deep neural network models have been proven to be very successful in image classification tasks, also for medical diagnosis, but their main concern is its lack of interpretability. They use to work as intuition machines with high…

Machine Learning · Computer Science 2019-04-26 Jordi de la Torre , Aida Valls , Domenec Puig

One major challenge in the medication of Parkinson's disease is that the severity of the disease, reflected in the patients' motor state, cannot be measured using accessible biomarkers. Therefore, we develop and examine a variety of…

Machine Learning · Computer Science 2019-04-26 Jann Goschenhofer , Franz MJ Pfister , Kamer Ali Yuksel , Bernd Bischl , Urban Fietzek , Janek Thomas

Background and objectives: Parkinson's disease is a neurological disorder that affects the motor system producing lack of coordination, resting tremor, and rigidity. Impairments in handwriting are among the main symptoms of the disease.…

Machine Learning · Computer Science 2020-02-14 C. D. Rios-Urrego , J. C. Vásquez-Correa , J. F. Vargas-Bonilla , E. Nöth , F. Lopera , J. R. Orozco-Arroyave

The ability to interpret machine learning model decisions is critical in such domains as healthcare, where trust in model predictions is as important as their accuracy. Inspired by the development of prototype parts-based deep neural…

Machine Learning · Computer Science 2026-03-06 Jacek Karolczak , Jerzy Stefanowski

Parkinson's disease (PD) is a neuro-degenerative disorder that affects movement, speech, and coordination. Timely diagnosis and treatment can improve the quality of life for PD patients. However, access to clinical diagnosis is limited in…

Computer Vision and Pattern Recognition · Computer Science 2024-02-19 Md. Zarif Ul Alam , Md Saiful Islam , Ehsan Hoque , M Saifur Rahman

Parkinson's Disease (PD) is a progressive neurodegenerative disorder that significantly impacts both motor and non-motor functions, including speech. Early and accurate recognition of PD through speech analysis can greatly enhance patient…

Numerical Analysis · Mathematics 2024-07-24 Niloofar Fadavi , Nazanin Fadavi

In recent years, Artificial Intelligence (AI) has proven its relevance for medical decision support. However, the "black-box" nature of successful AI algorithms still holds back their wide-spread deployment. In this paper, we describe an…

Computer Vision and Pattern Recognition · Computer Science 2021-07-23 Gwenolé Quellec , Hassan Al Hajj , Mathieu Lamard , Pierre-Henri Conze , Pascale Massin , Béatrice Cochener

Parkinson's Disease PD is a progressive neurodegenerative disorder that affects motor and cognitive functions with early diagnosis being critical for effective clinical intervention Electroencephalography EEG offers a noninvasive and…

This work proposes the use of 3D convolutional variational autoencoders (CVAEs) to trace the changes and symptomatology produced by neurodegeneration in Parkinson's disease (PD). In this work, we present a novel approach to detect and…

Image and Video Processing · Electrical Eng. & Systems 2023-05-15 E. Delgado de las Heras , F. J. Martinez-Murcia , I. A. Illán , C. Jiménez-Mesa , D. Castillo-Barnes , J. Ramírez , J. M. Górriz

Explainable AI has emerged to be a key component for black-box machine learning approaches in domains with a high demand for reliability or transparency. Examples are medical assistant systems, and applications concerned with the General…

Machine Learning · Computer Science 2021-05-18 Johannes Rabold , Gesina Schwalbe , Ute Schmid

In this paper, we explore the possibility to apply machine learning to make diagnostic predictions using discomfort drawings. A discomfort drawing is an intuitive way for patients to express discomfort and pain related symptoms. These…

Machine Learning · Computer Science 2016-12-06 Cheng Zhang , Hedvig Kjellstrom , Bo C. Bertilson

Parkinson's disease (PD) is a progressive neurodegenerative disorder that results in a variety of motor dysfunction symptoms, including tremors, bradykinesia, rigidity and postural instability. The diagnosis of PD mainly relies on clinical…

Computer Vision and Pattern Recognition · Computer Science 2022-07-15 Haozheng Zhang , Edmond S. L. Ho , Xiatian Zhang , Hubert P. H. Shum

Limited accessibility to neurological care leads to underdiagnosed Parkinson's Disease (PD), preventing early intervention. Existing AI-based PD detection methods primarily focus on unimodal analysis of motor or speech tasks, overlooking…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Md Saiful Islam , Tariq Adnan , Jan Freyberg , Sangwu Lee , Abdelrahman Abdelkader , Meghan Pawlik , Cathe Schwartz , Karen Jaffe , Ruth B. Schneider , E Ray Dorsey , Ehsan Hoque

Deep learning methods have shown great success in several domains as they process a large amount of data efficiently, capable of solving complex classification, forecast, segmentation, and other tasks. However, they come with the inherent…

Artificial Intelligence · Computer Science 2020-11-20 Dominique Mercier , Andreas Dengel , Sheraz Ahmed

The lack of interpretability of existing CNN-based hand detection methods makes it difficult to understand the rationale behind their predictions. In this paper, we propose a novel neural network model, which introduces interpretability…

Computer Vision and Pattern Recognition · Computer Science 2020-01-20 Dan Liu , Libo Zhang , Tiejian Luo , Lili Tao , Yanjun Wu