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Interpretable brain network models for disease prediction are of great value for the advancement of neuroscience. GNNs are promising to model complicated network data, but they are prone to overfitting and suffer from poor interpretability,…

Machine Learning · Computer Science 2021-07-13 Hejie Cui , Wei Dai , Yanqiao Zhu , Xiaoxiao Li , Lifang He , Carl Yang

Detecting Parkinson's Disease in its early stages using EEG data presents a significant challenge. This paper introduces a novel approach, representing EEG data as a 15-variate series of bandpower and peak frequency values/coefficients. The…

Neurons and Cognition · Quantitative Biology 2023-12-11 Amarpal Sahota , Amber Roguski , Matthew W. Jones , Michal Rolinski , Alan Whone , Raul Santos-Rodriguez , Zahraa S. Abdallah

Automated diagnosis prediction from medical images is a valuable resource to support clinical decision-making. However, such systems usually need to be trained on large amounts of annotated data, which often is scarce in the medical domain.…

Computer Vision and Pattern Recognition · Computer Science 2023-06-29 Chantal Pellegrini , Matthias Keicher , Ege Özsoy , Petra Jiraskova , Rickmer Braren , Nassir Navab

Parkinson's disease is a progressive neurodegenerative disorder affecting motor and non-motor functions, with speech impairments among its earliest symptoms. Speech impairments offer a valuable diagnostic opportunity, with machine learning…

Machine Learning · Computer Science 2025-04-25 Lorenzo Simone , Mauro Giuseppe Camporeale , Vito Marco Rubino , Vincenzo Gervasi , Giovanni Dimauro

Parkinson's Disease (PD) is a neurodegenerative disorder characterized by motor symptoms, including altered voice production in the early stages. Early diagnosis is crucial not only to improve PD patients' quality of life but also to…

Audio and Speech Processing · Electrical Eng. & Systems 2025-01-15 Maksim Siniukov , Ellie Xing , Sanaz Attaripour Isfahani , Mohammad Soleymani

Predicting the response of a cancer cell line to a therapeutic drug is pivotal for personalized medicine. Despite numerous deep learning methods that have been developed for drug response prediction, integrating diverse information about…

Machine Learning · Computer Science 2025-03-31 Haoyuan Shi , Tao Xu , Xiaodi Li , Qian Gao , Zhiwei Xiong , Junfeng Xia , Zhenyu Yue

Parkinson's disease (PD) is a progressive neurological disorder that impairs movement control, leading to symptoms such as tremors, stiffness, and bradykinesia. Many researchers analyzing handwriting data for PD detection typically rely on…

Signal Processing · Electrical Eng. & Systems 2024-12-25 Jungpil Shin , Abu Saleh Musa Miah , Koki Hirooka , Md. Al Mehedi Hasan , Md. Maniruzzaman

Parkinson's disease (PD) is a slowly progressing neurodegenerative disease with early manifestation of motor signs. Recently, there has been a growing interest in developing automatic tools that can assess motor function in PD patients.…

Information Retrieval · Computer Science 2018-05-04 Liron Allerhand , Brit Youngmann , Elad Yom-Tov , David Arkadir

At present, the vast majority of human subjects with neurological disease are still diagnosed through in-person assessments and qualitative analysis of patient data. In this paper, we propose to use Topological Data Analysis (TDA) together…

Machine Learning · Computer Science 2020-05-07 Afra Nawar , Farhan Rahman , Narayanan Krishnamurthi , Anirudh Som , Pavan Turaga

Traditional deep learning interpretability methods which are suitable for model users cannot explain network behaviors at the global level and are inflexible at providing fine-grained explanations. As a solution, concept-based explanations…

Human-Computer Interaction · Computer Science 2022-10-26 Jinbin Huang , Aditi Mishra , Bum Chul Kwon , Chris Bryan

Parkinson's disease (PD) is a debilitating neurodegenerative disease that has severe impacts on an individual's quality of life. Compared with structural and functional MRI-based biomarkers for the disease, electroencephalography (EEG) can…

Machine Learning · Computer Science 2024-08-05 Christopher Neves , Yong Zeng , Yiming Xiao

Parkinson's disease (PD), a severe and progressive neurological illness, affects millions of individuals worldwide. For effective treatment and management of PD, an accurate and early diagnosis is crucial. This study presents a deep…

Signal Processing · Electrical Eng. & Systems 2023-08-16 Niloufar Delfan , Mohammadreza Shahsavari , Sadiq Hussain , Robertas Damaševičius , U. Rajendra Acharya

In this paper we evaluate the suitability of handwriting patterns as potential biomarkers to model Parkinson disease (PD). Although the study of PD is attracting the interest of many researchers around the world, databases to evaluate…

Computer Vision and Pattern Recognition · Computer Science 2019-03-21 R. Castrillon , A. Acien , J. R. Orozco-Arroyave , A. Morales , J. F. Vargas , R. Vera-Rodrıguez , J. Fierrez , J. Ortega-Garcia , A. Villegas

Diagnosis prediction is a critical task in healthcare, where timely and accurate identification of medical conditions can significantly impact patient outcomes. Traditional machine learning and deep learning models have achieved notable…

Machine Learning · Computer Science 2025-01-09 Qiuhao Lu , Rui Li , Elham Sagheb , Andrew Wen , Jinlian Wang , Liwei Wang , Jungwei W. Fan , Hongfang Liu

The rapid emergence of highly adaptable and reusable artificial intelligence (AI) models is set to revolutionize the medical field, particularly in the diagnosis and management of Parkinson's disease (PD). Currently, there are no effective…

Machine Learning · Computer Science 2025-02-18 Aite Zhao , Yongcan Liu , Xinglin Yu , Xinyue Xing

A widely used test for the diagnosis of Parkinson's disease (PD) and Essential tremor (ET) is hand-drawn shapes,where the analysis is observationally performed by the examining neurologist. This method is subjective and is prone to bias…

Computer Vision and Pattern Recognition · Computer Science 2020-06-23 Nabeel Seedat , Vered Aharonson , Ilana Schlesinger

Although explainability is essential in the clinical diagnosis, most deep learning models still function as black boxes without elucidating their decision-making process. In this study, we investigate the explainable model development that…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Yunhe Gao , Difei Gu , Mu Zhou , Dimitris Metaxas

In the world, about 7 to 10 million elderly people are suffering from Parkinson's Disease (PD) disease. Parkinson's disease is a common neurological degenerative disease, and its clinical characteristics are Tremors, rigidity, bradykinesia,…

Computer Vision and Pattern Recognition · Computer Science 2020-08-07 Elcin Huseyn

Parkinson's disease is the world's fastest-growing neurological disorder. Research to elucidate the mechanisms of Parkinson's disease and automate diagnostics would greatly improve the treatment of patients with Parkinson's disease. Current…

Machine Learning · Computer Science 2024-02-20 Charlie Tran , Kai Shen , Kang Liu , Akshay Ashok , Adolfo Ramirez-Zamora , Jinghua Chen , Yulin Li , Ruogu Fang

Parkinson's disease (PD) is a common neurodegenerative disorder that severely diminishes patients' quality of life. Its global prevalence has increased markedly in recent decades. Current diagnostic workflows are complex and heavily reliant…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Shuai Shao , Yan Wang , Shu Jiang , Shiyuan Zhao , Di Yang , Jiangtao Wang , Yutong Bai , Jianguo Zhang