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Electronic Health Records (EHRs) offer considerable potential for clinical prediction, but their complexity and heterogeneity challenge traditional machine learning. Domain-specific EHR foundation models trained on unlabeled EHR data have…

Current medical language models, adapted from large language models (LLMs), typically predict ICD code-based diagnosis from electronic health records (EHRs) because these labels are readily available. However, ICD codes do not capture the…

Computation and Language · Computer Science 2025-12-09 Wenhao Li , Hongkuan Zhang , Hongwei Zhang , Zhengxu Li , Zengjie Dong , Yafan Chen , Niranjan Bidargaddi , Hong Liu

Although Large Language Models (LLMs) demonstrate significant capabilities, their reliance on parametric knowledge often leads to inaccuracies. Retrieval Augmented Generation (RAG) mitigates this by incorporating external knowledge, but…

Artificial Intelligence · Computer Science 2025-11-04 Hailong Yin , Bin Zhu , Jingjing Chen , Chong-Wah Ngo

Electrocardiogram (ECG) is widely used in healthcare applications, such as arrhythmia detection and sleep monitoring, making accurate ECG analysis critically essential. Traditional deep learning models for ECG are task-specific, with…

Signal Processing · Electrical Eng. & Systems 2025-10-14 Yu Han , Vittorio Murino , Xiaofeng Liu , Xiang Zhang , Cheng Ding

Large Language Models (LLMs) have enabled a wide range of applications through their powerful capabilities in language understanding and generation. However, as LLMs are trained on static corpora, they face difficulties in addressing…

Computation and Language · Computer Science 2025-10-13 Yongjie Wang , Yue Yu , Kaisong Song , Jun Lin , Zhiqi Shen

Retrieval-Augmented Generation (RAG) is a promising approach for mitigating the hallucination of large language models (LLMs). However, existing research lacks rigorous evaluation of the impact of retrieval-augmented generation on different…

Computation and Language · Computer Science 2023-12-21 Jiawei Chen , Hongyu Lin , Xianpei Han , Le Sun

Large Language Models (LLMs) have significantly enhanced the capabilities of information access systems, especially with retrieval-augmented generation (RAG). Nevertheless, the evaluation of RAG systems remains a barrier to continued…

Information Retrieval · Computer Science 2025-04-22 Ronak Pradeep , Nandan Thakur , Shivani Upadhyay , Daniel Campos , Nick Craswell , Jimmy Lin

In the current paradigm of image captioning, deep learning models are trained to generate text from image embeddings of latent features. We challenge the assumption that fine-tuning of large, bespoke models is required to improve model…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Steven Song , Anirudh Subramanyam , Irene Madejski , Robert L. Grossman

Large Language Models (LLMs) have shown remarkable progress in medical question answering (QA), yet their effectiveness remains predominantly limited to English due to imbalanced multilingual training data and scarce medical resources for…

In the domain of cardiovascular healthcare, the Electrocardiogram (ECG) serves as a critical, non-invasive diagnostic tool. Although recent strides in self-supervised learning (SSL) have been promising for ECG representation learning, these…

Signal Processing · Electrical Eng. & Systems 2023-09-15 Che Liu , Zhongwei Wan , Sibo Cheng , Mi Zhang , Rossella Arcucci

Retrieval-Augmented Generation (RAG) systems are emerging as a key approach for grounding Large Language Models (LLMs) in external knowledge, addressing limitations in factual accuracy and contextual relevance. However, there is a lack of…

Software Engineering · Computer Science 2025-09-25 Md Toufique Hasan , Muhammad Waseem , Kai-Kristian Kemell , Ayman Asad Khan , Mika Saari , Pekka Abrahamsson

Label ambiguity is an inherent problem in real-world electrocardiogram (ECG) diagnosis, arising from overlapping conditions and diagnostic disagreement. However, current ECG models are trained under the assumption of clean and non-ambiguous…

Machine Learning · Computer Science 2025-12-15 Sana Rahmani , Javad Hashemi , Ali Etemad

The electrocardiogram (ECG) is one of the most commonly used non-invasive, convenient medical monitoring tools that assist in the clinical diagnosis of heart diseases. Recently, deep learning (DL) techniques, particularly self-supervised…

Machine Learning · Computer Science 2023-03-23 Jun Li , Che Liu , Sibo Cheng , Rossella Arcucci , Shenda Hong

With the widespread application of electroencephalography (EEG) in neuroscience and clinical practice, efficiently retrieving and semantically interpreting large-scale, multi-source, heterogeneous EEG data has become a pressing challenge.…

Computation and Language · Computer Science 2025-10-14 Yi Wang , Haoran Luo , Lu Meng , Ziyu Jia , Xinliang Zhou , Qingsong Wen

This paper examines the application of ChatGPT, a large language model (LLM), for question-and-answer (Q&A) tasks in the highly specialized field of nuclear data. The primary focus is on evaluating ChatGPT's performance on a curated test…

Computation and Language · Computer Science 2024-09-04 Muhammad Anwar , Mischa de Costa , Issam Hammad , Daniel Lau

Graph-based Retrieval-Augmented Generation (RAG) has proven effective in integrating external knowledge into large language models (LLMs), improving their factual accuracy, adaptability, interpretability, and trustworthiness. A number of…

Information Retrieval · Computer Science 2026-04-28 Yingli Zhou , Yaodong Su , Youran Sun , Shu Wang , Taotao Wang , Runyuan He , Yongwei Zhang , Sicong Liang , Xilin Liu , Yuchi Ma , Yixiang Fang

Medical large vision-language Models (Med-LVLMs) have shown promise in clinical applications but suffer from factual inaccuracies and unreliable outputs, posing risks in real-world diagnostics. While RAG has emerged as a potential solution,…

Computation and Language · Computer Science 2026-05-05 Zhe Chen , Yusheng Liao , Zhiyuan Zhu , Haolin Li , Hongcheng Liu , Yanfeng Wang , Yu Wang

Electrocardiogram (ECG) foundation models represent a paradigm shift from task-specific pipelines to generalizable architectures pre-trained on large-scale unlabeled waveform data. This survey presents a unified and deployment-aware review…

Signal Processing · Electrical Eng. & Systems 2026-04-06 Mudassir Hasan Khan , Ahmad Nayfeh , Mudassir Masood , Ali Ahmad Al-Shaikhi , Muhammad Mahboob Ur Rahman , Tareq Y. Al-Naffouri

Zero-shot medical image classification is a critical process in real-world scenarios where we have limited access to all possible diseases or large-scale annotated data. It involves computing similarity scores between a query medical image…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Jiaxiang Liu , Tianxiang Hu , Yan Zhang , Xiaotang Gai , Yang Feng , Zuozhu Liu

This paper presents the development and evaluation of a Retrieval-Augmented Generation (RAG) system for querying the United Kingdom's National Institute for Health and Care Excellence (NICE) clinical guidelines using Large Language Models…

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