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Current Large Language Models (LLMs) exhibit significant limitations, notably in structured, interpretable, and verifiable medical reasoning, alongside practical deployment challenges related to computational resources and data privacy.…

Computation and Language · Computer Science 2025-06-06 Boqin Zhuang , Chenxiao Song , Huitong Lu , Jiacheng Qiao , Mingqian Liu , Mingxing Yu , Ping Hong , Rui Li , Xiaoxia Song , Xiangjun Xu , Xu Chen , Yaoyao Ma , Yujie Gao

Safe and trustworthy use of Large Language Models (LLM) in the processing of healthcare documents and scientific papers could substantially help clinicians, scientists and policymakers in overcoming information overload and focusing on the…

Large Language Models (LLMs) hold significant promise for improving clinical decision support and reducing physician burnout by synthesizing complex, longitudinal cancer Electronic Health Records (EHRs). However, their implementation in…

Computation and Language · Computer Science 2026-01-12 Dongchen Li , Jitao Liang , Wei Li , Xiaoyu Wang , Longbing Cao , Kun Yu

Question answering systems (QA) utilizing Large Language Models (LLMs) heavily depend on the retrieval component to provide them with domain-specific information and reduce the risk of generating inaccurate responses or hallucinations.…

Computation and Language · Computer Science 2024-06-11 Ashkan Alinejad , Krtin Kumar , Ali Vahdat

Existing low-rank adaptation (LoRA) methods face challenges on sparse large language models (LLMs) due to the inability to maintain sparsity. Recent works introduced methods that maintain sparsity by augmenting LoRA techniques with…

Computation and Language · Computer Science 2025-01-16 Yuxuan Hu , Jing Zhang , Xiaodong Chen , Zhe Zhao , Cuiping Li , Hong Chen

The applications of Large Language Models (LLMs) in political science are rapidly expanding. This paper demonstrates how LLMs, when augmented with predefined functions and specialized tools, can serve as dynamic agents capable of…

Computation and Language · Computer Science 2025-10-08 Joseph R. Loffredo , Suyeol Yun

Large language models (LLMs) significantly enhance the performance of various applications, but they are computationally intensive and energy-demanding. This makes it challenging to deploy them on devices with limited resources, such as…

Machine Learning · Computer Science 2025-12-22 Yang Li , Daniel Agyei Asante , Changsheng Zhao , Ernie Chang , Yangyang Shi , Vikas Chandra

Large Language Models (LLMs) are increasingly deployed in medicine. However, their utility in non-generative clinical prediction, often presumed inferior to specialized models, remains under-evaluated, leading to ongoing debate within the…

Effectively integrating molecular graph structures with Large Language Models (LLMs) is a key challenge in drug discovery. Most existing multi-modal alignment methods typically process these structures by fine-tuning the LLM or adding a…

Machine Learning · Computer Science 2025-10-15 Tao Yin , Xiaohong Zhang , Jiacheng Zhang , Li Huang , Zhibin Zhang , Yuansong Zeng , Jin Xie , Meng Yan

Federated fine-tuning has emerged as a promising approach to adapt foundation models to downstream tasks using decentralized data. However, real-world deployment remains challenging due to the high computational and communication demands of…

Machine Learning · Computer Science 2025-08-21 Yajie Zhou , Xiaoyi Pang , Zhibo Wang

This study evaluates the performance of several Large Language Models (LLMs) on MedRedQA, a dataset of consumer-based medical questions and answers by verified experts extracted from the AskDocs subreddit. While LLMs have shown proficiency…

Computation and Language · Computer Science 2025-01-03 Moaiz Abrar , Yusuf Sermet , Ibrahim Demir

Large language models (LLMs) have shown amazing capabilities in knowledge memorization and the present. However, when it comes to domain-specific knowledge and downstream tasks like medical, general LLMs are often unable to give precise…

Computation and Language · Computer Science 2024-06-06 Maojun Sun

This paper presents a novel pipeline for 2D keypoint estima- tion of surgical tools by leveraging Vision Language Models (VLMs) fine- tuned using a low rank adjusting (LoRA) technique. Unlike traditional Convolutional Neural Network (CNN)…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Krit Duangprom , Tryphon Lambrou , Binod Bhattarai

Recent advancements in Large Language Models (LLMs) have emphasized the critical role of fine-tuning (FT) techniques in adapting LLMs to specific tasks, especially when retraining from scratch is computationally infeasible. Fine-tuning…

Artificial Intelligence · Computer Science 2025-10-23 Xiao Han , Zimo Zhao , Wanyu Wang , Maolin Wang , Zitao Liu , Yi Chang , Xiangyu Zhao

Large language models (LLMs) have achieved remarkable performance on diverse benchmarks, yet existing evaluation practices largely rely on coarse summary metrics that obscure underlying reasoning abilities. In this work, we propose novel…

Methodology · Statistics 2026-03-17 Jia Liu , Zhiyu Xu , Yuqi Gu

Generating discharge summaries is a crucial yet time-consuming task in clinical practice, essential for conveying pertinent patient information and facilitating continuity of care. Recent advancements in large language models (LLMs) have…

Computation and Language · Computer Science 2025-07-01 Yiming Li , Fang Li , Kirk Roberts , Licong Cui , Cui Tao , Hua Xu

Due to the high memory and computational costs associated with large language models (LLMs), model compression techniques such as quantization, which reduces inference costs, and parameter-efficient fine-tuning (PEFT) methods like Low-Rank…

Machine Learning · Computer Science 2025-07-23 Hyesung Jeon , Yulhwa Kim , Jae-joon Kim

The machine learning community has witnessed impressive advancements since large language models (LLMs) first appeared. Yet, their massive memory consumption has become a significant roadblock to large-scale training. For instance, a 7B…

Machine Learning · Computer Science 2024-12-30 Rui Pan , Xiang Liu , Shizhe Diao , Renjie Pi , Jipeng Zhang , Chi Han , Tong Zhang

Parameter-efficient methods like LoRA have revolutionised large language model (LLM) fine-tuning. ReLoRA extends this idea to pretraining by repeatedly merging and reinitialising low-rank adapters, increasing cumulative rank while keeping…

Computation and Language · Computer Science 2025-10-03 Yuval Weiss , David Demitri Africa , Paula Buttery , Richard Diehl Martinez

This study examines whether Low-Rank Adaptation (LoRA) fine-tuned Large Language Models (LLMs) can approximate the performance of fully fine-tuned models in generating human-interpretable decisions and explanations for malware…

Cryptography and Security · Computer Science 2025-11-26 Stephen C. Gravereaux , Sheikh Rabiul Islam
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