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The liver is the most involved organ by distant metastasis in colon-rectal cancer (CRC) patients and it comes necessary to be aware of the mutational status of the lesions to correctly design the best individual treatment. So far, efforts…

Image and Video Processing · Electrical Eng. & Systems 2024-01-26 Daniele Perlo , Luca Berton , Alessia Delpiano , Francesca Menchini , Stefano Tibaldi , Marco Grosso , Paolo Fonio

Colorectal cancer (CRC) remains a significant cause of cancer-related mortality, despite the widespread implementation of prophylactic initiatives aimed at detecting and removing precancerous polyps. Although screening effectively reduces…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Ahmed Rahu , Brian Shula , Brandon Combs , Aqsa Sultana , Surendra P. Singh , Vijayan K. Asari , Derrick Forchetti

Accurate prediction of biochemical recurrence (BCR) after radical prostatectomy is critical for guiding adjuvant treatment and surveillance decisions in prostate cancer. However, existing clinicopathological risk models reduce complex…

Colorectal liver metastasis is one of most aggressive liver malignancies. While the definition of lesion type based on CT images determines the diagnosis and therapeutic strategy, the discrimination between cancerous and non-cancerous…

Computer Vision and Pattern Recognition · Computer Science 2019-01-29 Francisco Perdigon Romero , Andre Diler , Gabriel Bisson-Gregoire , Simon Turcotte , Real Lapointe , Franck Vandenbroucke-Menu , An Tang , Samuel Kadoury

This paper proposes a novel multimodal deep learning framework integrating bidirectional LSTM, multi-head attention mechanism, and variational mode decomposition (BiLSTM-AM-VMD) for early liver cancer diagnosis. Using heterogeneous data…

Machine Learning · Computer Science 2025-09-03 Cheng Cheng , Zeping Chen , Xavier Wang

We address the problem of supporting radiologists in the longitudinal management of lung cancer. Therefore, we proposed a deep learning pipeline, composed of four stages that completely automatized from the detection of nodules to the…

Image and Video Processing · Electrical Eng. & Systems 2021-03-29 Xavier Rafael-Palou , Anton Aubanell , Mario Ceresa , Vicent Ribas , Gemma Piella , Miguel A. González Ballester

Dynamic treatment regimes (DTR) are sequential decision rules corresponding to several stages of intervention. Each rule maps patients' covariates to optional treatments. The optimal dynamic treatment regime is the one that maximizes the…

Methodology · Statistics 2023-10-10 Zhishuai Liu , Zishu Zhan , Jian Liu , Danhui Yi , Cunjie Lin , Yufei Yang

Deep learning has been shown to be useful to detect breast cancer metastases by analyzing whole slide images of sentinel lymph nodes. However, it requires extensive scanning and analysis of all the lymph nodes slides for each case. Our deep…

Computer Vision and Pattern Recognition · Computer Science 2023-01-18 Kareem Allam , Xiaohong Iris Wang , Songlin Zhang , Jianmin Ding , Kevin Chiu , Karan Saluja , Amer Wahed , Hongxia Sun , Andy N. D. Nguyen

Northern Europe has the second highest mortality rate of melanoma globally. In 2020, the mortality rate of melanoma rose to 1.9 per 100 000 habitants. Melanoma prognosis is based on a pathologist's subjective visual analysis of the…

Image and Video Processing · Electrical Eng. & Systems 2023-03-13 Christopher Andreassen , Saul Fuster , Helga Hardardottir , Emiel A. M. Janssen , Kjersti Engan

Automatic lymph node (LN) segmentation and detection for cancer staging are critical. In clinical practice, computed tomography (CT) and positron emission tomography (PET) imaging detect abnormal LNs. Despite its low contrast and variety in…

Image and Video Processing · Electrical Eng. & Systems 2022-12-23 Al-Akhir Nayan , Boonserm Kijsirikul , Yuji Iwahori

Colorectal cancer (CRC) remains the third most prevalent malignancy globally, with approximately 154,000 new cases and 54,000 projected deaths anticipated for 2025. The recent advancement of foundation models in computational pathology has…

Computer Vision and Pattern Recognition · Computer Science 2025-10-17 Usama Sajjad , Abdul Rehman Akbar , Ziyu Su , Deborah Knight , Wendy L. Frankel , Metin N. Gurcan , Wei Chen , Muhammad Khalid Khan Niazi

Cervical cancer, the fourth leading cause of cancer in women globally, requires early detection through Pap smear tests to identify precancerous changes and prevent disease progression. In this study, we performed a focused analysis by…

Image and Video Processing · Electrical Eng. & Systems 2025-05-22 Abdul Samad Shaik , Shashaank Mattur Aswatha , Rahul Jashvantbhai Pandya

Prognostic information at diagnosis has important implications for cancer treatment and monitoring. Although cancer staging, histopathological assessment, molecular features, and clinical variables can provide useful prognostic insights,…

Colorectal polyps are generally benign alterations that, if not identified promptly and managed successfully, can progress to cancer and cause affectations on the colon mucosa, known as adenocarcinoma. Today advances in Deep Learning have…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Daniela L. Ramos , Hector J. Hortua

With the long-term rapid increase in incidences of colorectal cancer (CRC), there is an urgent clinical need to improve risk stratification. The conventional pathology report is usually limited to only a few histopathological features.…

Image and Video Processing · Electrical Eng. & Systems 2020-07-08 Christian Abbet , Inti Zlobec , Behzad Bozorgtabar , Jean-Philippe Thiran

Colorectal cancer (CRC) is a leading worldwide cause of cancer-related mortality, and the role of prompt precise detection is of paramount interest in improving patient outcomes. Conventional diagnostic methods such as colonoscopy and…

Image and Video Processing · Electrical Eng. & Systems 2025-10-29 Ovi Sarkar , Md Shafiuzzaman , Md. Faysal Ahamed , Golam Mahmud , Muhammad E. H. Chowdhury

Deep learning models (DLMs) frequently achieve accurate segmentation and classification of tumors from medical images. However, DLMs lacking feedback on their image segmentation mechanisms, such as Dice coefficients and confidence in their…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Elhoucine Elfatimi , Pratik Shah

Deep learning has shown tremendous progress in a wide range of digital pathology and medical image classification tasks. Its integration into safe clinical decision-making support requires robust and reliable models. However, real-world…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Abdur R. Fayjie , Jutika Borah , Florencia Carbone , Jan Tack , Patrick Vandewalle

Colorectal cancer (CRC) is a significant global health concern, and early detection through screening plays a critical role in reducing mortality. While deep learning models have shown promise in improving polyp detection, classification,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Jia Yu , Yan Zhu , Peiyao Fu , Tianyi Chen , Junbo Huang , Quanlin Li , Pinghong Zhou , Zhihua Wang , Fei Wu , Shuo Wang , Xian Yang

Most early-stage colorectal cancer (CRC) patients can be cured by surgery alone, and only certain high-risk early-stage CRC patients benefit from adjuvant chemotherapies. However, very few validated biomarkers are available to accurately…

Machine Learning · Computer Science 2021-11-08 Xingyu Li , Jitendra Jonnagaddala , Shuhua Yang , Hong Zhang , Xu Steven Xu