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Multiplexed imaging data are revolutionizing our understanding of the composition and organization of tissues and tumors. A critical aspect of such tissue profiling is quantifying the spatial relationship relationships among cells at…

Quantitative Methods · Quantitative Biology 2024-05-06 Ajit J. Nirmal , Peter K. Sorger

Transport-Based Morphometry (TBM) has emerged as a new framework for 3D medical image analysis. By embedding images into a transport domain via invertible transformations, TBM facilitates effective classification, regression, and other…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Hongyu Kan , Kristofor Pas , Ivan Medri , Naqib Sad Pathan , Natasha Ironside , Shinjini Kundu , Jingjia He , Gustavo Kunde Rohde

This paper introduces advanced techniques of Topological Data Analysis (TDA) for unsupervised anomaly detection and customer segmentation in banking data. Using the Mapper algorithm and persistent homology, we develop unsupervised…

Machine Learning · Computer Science 2025-08-21 Leonardo Aldo Alejandro Barberi , Linda Maria De Cave

Interpretability is becoming an active research topic as machine learning (ML) models are more widely used to make critical decisions. Tabular data is one of the most commonly used modes of data in diverse applications such as healthcare…

Machine Learning · Statistics 2021-12-01 Amirata Ghorbani , Dina Berenbaum , Maor Ivgi , Yuval Dafna , James Zou

This research addresses a new tool for data analysis known as Topological Data Analysis TDA It underlies an area of Mathematics known as Combinatorial Algebra or more recently Algebraic Topology which through making strong use of…

Statistics Theory · Mathematics 2021-06-29 Daniel Trejo Medina , Karla Sarai Jimenez

Data visualization is the process by which data of any size or dimensionality is processed to produce an understandable set of data in a lower dimensionality, allowing it to be manipulated and understood more easily by people. The goal of…

Graphics · Computer Science 2021-07-06 Alexander Kiefer , Md. Khaledur Rahman

A frequent task in exploratory data analysis consists in examining pairwise dependencies between data variables. Popular approaches include visualizing correlation or scatter plot matrices. However, both methods can be misleading. The…

Applications · Statistics 2022-04-04 Arturo Erdely , Manuel Rubio-Sanchez

Information visualization is essential in making sense out of large data sets. Often, high-dimensional data are visualized as a collection of points in 2-dimensional space through dimensionality reduction techniques. However, these…

Computational Geometry · Computer Science 2009-07-16 Emden R. Gansner , Yifan Hu , Stephen G. Kobourov

Exploratory visual data analysis tools empower data analysts to efficiently and intuitively explore data insights throughout the entire analysis cycle. However, the gap between common programmatic analysis (e.g., within computational…

Human-Computer Interaction · Computer Science 2025-01-08 Yue Yu , Leixian Shen , Fei Long , Huamin Qu , Hao Chen

Topological data analysis (TDA) detects geometric structure in biological data. However, many TDA algorithms are memory intensive and impractical for massive datasets. Here, we introduce a statistical protocol that reduces TDA's memory…

Quantitative Methods · Quantitative Biology 2025-09-05 Andrew J. Stier , Naichen Shi , Raed Al Kontar , Chad Giusti , Marc G. Berman

Scatter plots are widely recognized as fundamental tools for illustrating the relationship between two numerical variables. Despite this, based on solid theoretical foundations, scatter plots generated from pairs of continuous random…

Methodology · Statistics 2025-02-05 Arturo Erdely , Manuel Rubio-Sanchez

An understanding of the economic landscape in a world of ever increasing data necessitates representations of data that can inform policy, deepen understanding and guide future research. Topological Data Analysis offers a set of tools which…

Econometrics · Economics 2019-11-26 Pawel Dlotko , Simon Rudkin , Wanling Qiu

Recent advancements in graph representation learning have led to the emergence of condensed encodings that capture the main properties of a graph. However, even though these abstract representations are powerful for downstream tasks, they…

Machine Learning · Computer Science 2020-02-21 Cristian Bodnar , Cătălina Cangea , Pietro Liò

Boxplots and related visualization methods are widely used exploratory tools for taking a first look at collections of univariate variables. In this note an extension is provided that is specifically designed to detect and display…

Methodology · Statistics 2026-05-05 Camille M. Montalcini , Peter J. Rousseeuw

Data visualizations can reveal trends and patterns that are not otherwise obvious from the raw data or summary statistics. While visualizing low-dimensional data is relatively straightforward (for example, plotting the change in a variable…

Other Statistics · Statistics 2017-01-31 Andrew C. Heusser , Kirsten Ziman , Lucy L. W. Owen , Jeremy R. Manning

Topological data analysis (TDA) provides a growing body of tools for computing geometric and topological information about spaces from a finite sample of points. We present a new adaptive algorithm for finding provably dense samples of…

Algebraic Topology · Mathematics 2018-10-22 Emilie Dufresne , Parker B. Edwards , Heather A. Harrington , Jonathan D. Hauenstein

In the rapidly evolving era of Artificial Intelligence (AI), synthetic data are widely used to accelerate innovation while preserving privacy and enabling broader data accessibility. However, the evaluation of synthetic data remains…

The surge of data available on the Internet has driven the adoption of a wide range of computational methods for analyzing and extracting insights from large-scale data. Among these, Machine Learning (ML) has become a central paradigm,…

Computation and Language · Computer Science 2026-05-12 Adaku Uchendu , Thai Le

Despite data's crucial role in machine learning, most existing tools and research tend to focus on systems on top of existing data rather than how to interpret and manipulate data. In this paper, we propose DataLab, a unified data-oriented…

Machine Learning · Computer Science 2022-02-28 Yang Xiao , Jinlan Fu , Weizhe Yuan , Vijay Viswanathan , Zhoumianze Liu , Yixin Liu , Graham Neubig , Pengfei Liu

Understanding a visualization is a multi-level process. A reader must extract and extrapolate from numeric facts, understand how those facts apply to both the context of the data and other potential contexts, and draw or evaluate…

Human-Computer Interaction · Computer Science 2020-09-04 Alyxander Burns , Cindy Xiong , Steven Franconeri , Alberto Cairo , Narges Mahyar