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Translating statistical methods into reliable software is a persistent bottleneck in quantitative research. Existing AI code-generation tools produce code quickly but cannot guarantee faithful implementation -- a critical requirement for…

Software Engineering · Computer Science 2026-04-07 Tianzhu Qin , Yiqing Xu

Scientific workflows are a cornerstone of modern scientific computing. They are used to describe complex computational applications that require efficient and robust management of large volumes of data, which are typically stored/processed…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-03-03 Rafael Ferreira da Silva , Loïc Pottier , Tainã Coleman , Ewa Deelman , Henri Casanova

Computational reproducibility is fundamental to trustworthy science, yet remains difficult to achieve in practice across various research workflows, including Jupyter notebooks published alongside scholarly articles. Environment drift,…

Software Engineering · Computer Science 2026-04-02 Sheeba Samuel , Daniel Mietchen , Hemanta Lo , Martin Gaedke

Efficient reproduction of research papers is pivotal to accelerating scientific progress. However, the increasing complexity of proposed methods often renders reproduction a labor-intensive endeavor, necessitating profound domain expertise.…

Artificial Intelligence · Computer Science 2026-04-27 Xuanle Zhao , Zilin Sang , Yuxuan Li , Qi Shi , Weilun Zhao , Shuo Wang , Duzhen Zhang , Xu Han , Zhiyuan Liu , Maosong Sun

Notebooks provide an interactive environment for programmers to develop code, analyse data and inject interleaved visualizations in a single environment. Despite their flexibility, a major pitfall that data scientists encounter is…

Databases · Computer Science 2021-10-27 Pavle Subotić , Lazar Milikić , Milan Stojić

Tool use has turned large language models (LLMs) into powerful agents that can perform complex multi-step tasks by dynamically utilising external software components. However, these tools must be implemented in advance by human developers,…

Computation and Language · Computer Science 2025-06-02 Georg Wölflein , Dyke Ferber , Daniel Truhn , Ognjen Arandjelović , Jakob Nikolas Kather

Modern science clearly demands for a higher level of reproducibility and collaboration. To make research fully reproducible one has to take care of several aspects: research protocol description, data access, environment preservation,…

Computers and Society · Computer Science 2017-12-06 Andrey Ustyuzhanin , Timothy Daniel Head , Igor Babuschkin , Alexander Tiunov

Computational notebooks are notoriously prone to reproducibility failures. By permitting out-of-order cell execution, notebooks accumulate hidden state and implicit dependencies that cause interactive executions to silently diverge from…

Programming Languages · Computer Science 2026-05-05 Stephen N. Freund , Emery D. Berger , Cormac Flanagan , Eunice Jun

Generative artificial intelligence has revolutionized the exploration of chemical space, yet a critical bottleneck remains that a substantial fraction of generated molecules is synthetically inaccessible. Current solutions, such as post-hoc…

Artificial Intelligence · Computer Science 2025-12-24 Junren Li , Luhua Lai

The use of generative AI (GenAI) tools has fundamentally transformed software development. Central to this shift is prompt engineering, the practice of crafting textual prompts to guide GenAI tools in generating useful content. Although…

Software Engineering · Computer Science 2026-01-26 Daniel Otten , Trevor Stalnaker , Nathan Wintersgill , Oscar Chaparro , Denys Poshyvanyk

As the basis of generative AI, an autoregressive model requires the generation of a new token depending on all the previously generated tokens, which brings high quality but also restricts the model to generate tokens one by one, forming a…

Computation and Language · Computer Science 2025-07-02 Zixian Huang , Chenxu Niu , Yu Gu , Gengyang Xiao , Xinwei Huang , Gong Cheng

Calculating the similarities between a pair of genomic sequences is one of the most fundamental computational steps in genomic analysis. This step -- called sequence alignment -- is the computational bottleneck because: (1) it is…

Genomics · Quantitative Biology 2019-10-10 Mohammed H K Alser

Context: Jupyter Notebook has emerged as a versatile tool that transforms how researchers, developers, and data scientists conduct and communicate their work. As the adoption of Jupyter notebooks continues to rise, so does the interest from…

Software Engineering · Computer Science 2026-01-06 Md Saeed Siddik , Hao Li , Cor-Paul Bezemer

Reproducibility is increasingly important to statistical research, but many details are often omitted from the published version of complex statistical analyses. A reader's comprehension is limited to what the author concludes, without…

Computation · Statistics 2015-04-17 Dana Udwin , Ben Baumer

Due to the complexity of robotics, the reproducibility of results and experiments is one of the fundamental problems in robotics research. While the problem has been identified by the community, the approaches that address the problem…

Robotics · Computer Science 2018-01-26 Aljoscha Pörtner , Martin Hoffmann , Matthias König

Open-source scientific software is abundant, yet most tools remain difficult to compile, configure, and reuse, sustaining a small-workshop mode of scientific computing. This deployment bottleneck limits reproducibility, large-scale…

Software Engineering · Computer Science 2026-01-08 Yi Wang , Zhenting Huang , Zhaohan Ding , Ruoxue Liao , Yuan Huang , Xinzijian Liu , Jiajun Xie , Siheng Chen , Linfeng Zhang

The development of Artificial Intelligence (AI) enables humans to co-create content with machines. The unexpectedness of AI-generated content can bring inspiration and entertainment to users. However, the co-creation interactions are always…

Human-Computer Interaction · Computer Science 2023-07-11 Daijin Yang

Given a large and evolving codebase, the ability to automatically generate holistic, architecture-aware documentation that captures not only individual functions but also cross-file, cross-module, and system-level interactions remains an…

Software Engineering · Computer Science 2026-04-07 Anh Nguyen Hoang , Minh Le-Anh , Bach Le , Nghi D. Q. Bui

To increase performance and efficiency, systems use FPGAs as reconfigurable accelerators. A key challenge in designing these systems is partitioning computation between processors and an FPGA. An appropriate division of labor may be…

Hardware Architecture · Computer Science 2021-07-21 Endri Bezati , Mahyar Emami , Jörn Janneck , James Larus

We present \textsc{WisPaper}, an end-to-end agent system that transforms how researchers discover, organize, and track academic literature. The system addresses two fundamental challenges. (1)~\textit{Semantic search limitations}: existing…