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In this paper, we propose a virtual clinical trial for assessing the performance and identifying risks in closed-loop diabetes treatments. Virtual clinical trials enable fast and risk-free tests of many treatment variations for large…

Optimization and Control · Mathematics 2022-03-01 Asbjørn Thode Reenberg , Tobias K. S. Ritschel , Bernd Dammann , John Bagterp Jørgensen

False arrhythmia alarms in intensive care units (ICUs) are a significant challenge, contributing to alarm fatigue and potentially compromising patient safety. Ventricular tachycardia (VT) alarms are particularly difficult to detect…

Simulink is widely used in industrial design processes to model increasingly complex embedded control systems. Thus, their formal analysis is highly desirable. However, this comes with two major challenges: First, Simulink models often…

Systems and Control · Electrical Eng. & Systems 2025-06-18 Pauline Blohm , Felix Schulz , Lisa Willemsen , Anne Remke , Paula Herber

Cardiopulmonary resuscitation (CPR) is a critical life-saving procedure, and effective training benefits from self-directed practice beyond instructor-led sessions. In this paper, we propose a closed-loop CPR training glove that integrates…

Human-Computer Interaction · Computer Science 2026-03-09 Jaeyoung Moon , Mingzhuo Ma , Qifeng Yang , Youjin Choi , Seokhyun Hwang , Samuel Burden , Kyung-Joong Kim , Yiyue Luo

This dissertation proposes an electrocardiogram (ECG) tracking device that diagnoses cardiopulmonary problems using the Internet of Things (IoT) desired results. The initiative is built on the internet observing an electrocardiogram with…

Signal Processing · Electrical Eng. & Systems 2025-05-27 Hemalatha R J , Shubham Malhotra , Shivapanchakshari T G , Lokesh K , Dev Anand D , Samson Jebakumar S

Contemporary patient surveillance systems have streamlined central surveillance into the electronic health record interface. They are able to process the sheer volume of patient data by adopting machine learning approaches. However, these…

Computers and Society · Computer Science 2021-11-04 Nazifa M Shemonti , Shifat Uddin , Saifur Rahman , Tarem Ahmed , Mohammad Faisal Uddin

Although the circulatory system functions as a continuous source of physiological data, contemporary diagnostics remain bound to intermittent, time-delayed assessments. To resolve this, we present a framework for ubiquitous hematological…

Medical Physics · Physics 2026-02-27 Fatih E. Bilgen , Ozgur B. Akan

Emergency department (ED) crowding has been an increasing problem worldwide. Prior research has identified factors that contribute to ED crowding. However, the relationships between these remain incompletely understood. This study's…

We propose an integrated electromechanical model of the human heart, with focus on the left ventricle, wherein biophysically detailed models describe the different physical phenomena concurring to the cardiac function. We model the…

We aim to assess the effectiveness of feedback controlled resonant drift pacing as a method for low energy defibrillation. Antitachycardia pacing is the only low energy defibrillation approach to have gained clinical significance, but it is…

Tissues and Organs · Quantitative Biology 2009-11-13 S. W. Morgan , G. Plank , I. V. Biktasheva , V. N. Biktashev

Background and Objective: Computational ultrasound imaging has become a well-established methodology in the ultrasound community. Simulations of ultrasound sequences and images allow the study of innovative techniques in terms of emission…

Medical Physics · Physics 2022-03-08 Damien Garcia

Serious Illness Conversations (SICs), discussions about values and care preferences for patients with life-threatening illness, rarely occur in Emergency Departments (EDs), despite evidence that early conversations improve care alignment…

Human-Computer Interaction · Computer Science 2026-04-01 Menglin Zhao , Zhuorui Yong , Ruijia Guan , Kai-Wei Chang , Adrian Haimovich , Kei Ouchi , Timothy Bickmore , Zhan Zhang , Bingsheng Yao , Dakuo Wang , Smit Desai

Development of fast methods to conduct in silico experiments using computational models of cellular signaling is a promising approach toward advances in personalized medicine. However, software-based cellular network simulation has…

Molecular Networks · Quantitative Biology 2018-11-20 Kevin Gilboy , Khaled Sayed , Niteesh Sundaram , Kara Bocan , Natasa Miskov-Zivanov

A digital twin is a virtual replica of a real-world physical phenomena that uses mathematical modeling to characterize and simulate its defining features. By constructing digital twins for disease processes, we can perform in-silico…

Machine Learning · Computer Science 2024-11-04 Keying Kuang , Frances Dean , Jack B. Jedlicki , David Ouyang , Anthony Philippakis , David Sontag , Ahmed M. Alaa

Managing health-care records and information is an imperative necessity. Most patient health records are stored in separate systems and there are still huge paper trails of records that health-care providers must keep to comply with…

Computers and Society · Computer Science 2015-03-16 Turcu Cristina , Cerlinca Tudor , Cerlinca Marius , Prodan Remus , Turcu Cornel , Gîza Felicia

Reactive software calls for instrumentation methods that uphold the reactive attributes of systems. Runtime verification imposes another demand on the instrumentation, namely that the trace event sequences it reports to monitors are sound…

Software Engineering · Computer Science 2024-07-16 Luca Aceto , Duncan Paul Attard , Adrian Francalanza , Anna Ingólfsdóttir

The classification of electrocardiogram (ECG) signals is crucial for early detection of arrhythmias and other cardiac conditions. However, despite advances in machine learning, many studies fail to follow standardization protocols, leading…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Guilherme Silva , Pedro Silva , Gladston Moreira , Vander Freitas , Jadson Gertrudes , Eduardo Luz

As an alternative to both classical PID-type and modern model-based approaches to solving control problems, active disturbance rejection control (ADRC) has gained significant traction in recent years. With its simple tuning method and…

Systems and Control · Electrical Eng. & Systems 2024-08-01 Gernot Herbst

Patients in the intensive care unit (ICU) require constant and close supervision. To assist clinical staff in this task, hospitals use monitoring systems that trigger audiovisual alarms if their algorithms indicate that a patient's…

Machine Learning · Computer Science 2020-07-15 Patrick Schwab , Emanuela Keller , Carl Muroi , David J. Mack , Christian Strässle , Walter Karlen

We theoretically investigate the simulation of moving cavities in a superconducting circuit setup. In particular, we consider a recently proposed experimental scenario where the phase of the cavity field is used as a moving clock. By…

Quantum Physics · Physics 2019-08-21 Stefano Bosco , Joel Lindkvist , Göran Johansson
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