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Considering two rigid conical inclusions embedded in a membrane subject to lateral tension, we study the membrane-mediated interaction between these inclusions that originates from the hat-shaped membrane deformations associated with the…

Soft Condensed Matter · Physics 2009-10-31 T. R. Weikl , M. M. Kozlov , W. Helfrich

One of most intriguing problems of heterogeneous crystal nucleation in droplets is its strong enhancement in the contact mode (when the foreign particle is presumably in some kind of contact with the droplet surface) compared to the…

Statistical Mechanics · Physics 2016-09-28 Y. S. Djikaev , E. Ruckenstein

In this paper, attention is drawn to the importance of accounting for osmotic pressure when analyzing physiological effects on cellular structures in plasma medicine. Interaction of a weakly ionized plasma jet with a saline solution leads…

Medical Physics · Physics 2019-11-06 M. N. Shneider , M. Pekker

The collective motion of membrane lipids over hundred of nanometers and nanoseconds is essential for the formation of submicron complexes of lipids and proteins in the cell membrane. These dynamics are difficult to access experimentally and…

Biological Physics · Physics 2018-08-01 Sergio Panzuela , Rafael Delgado-Buscalioni

We demonstrate experimentally that the interactions between a pair of nonlocal spatial optical solitons in a nematic liquid crystal (NLC) can be controlled by the degree of nonlocality. For a given beam width, the degree of nonlocality can…

Optics · Physics 2007-05-23 Wei Hu , Tao Zhang , Qi Guo , Li Xuan , Sheng Lan

Previous experimental reports of long-range interactions in ionic liquids (ILs) stand in contradiction with theoretical predictions and numerical simulations. To provide insights into the literature discrepancies regarding the experimental…

Soft Condensed Matter · Physics 2026-03-24 Benjamin Cross , Léo Garcia , Elisabeth Charlaix , Patrick Kékicheff

Membrane proteins deform the surrounding lipid bilayer, which can lead to membrane-mediated interactions between neighboring proteins. Using the mechanosensitive channel of large conductance (MscL) as a model system, we demonstrate how the…

Biomolecules · Quantitative Biology 2016-11-03 Osman Kahraman , William S. Klug , Christoph A. Haselwandter

Hypothesis. Isoniazid is one of the primary drugs used in tuberculosis treatment. Isoniazid encapsulation in liposomal vesicles can improve drug therapeutic index and minimize toxic and side effects. In this work, we consider mixtures of…

The mammalian cell membrane is embedded with biomolecular condensates of protein and lipid clusters, which interact with an underlying viscoelastic cytoskeleton network to organize the cell surface and mechanically interact with the…

Soft Condensed Matter · Physics 2024-10-23 Daniel P. Arnold , Sho C. Takatori

Ionic liquids (ILs) feature a tailorable and wide range of structural, chemical and electronic properties that make this class of materials suitable to a broad variety of forefront applications in next-generation electronics. Yet, their…

Materials Science · Physics 2022-11-28 Irene Amiehe Essomba , Mauro Boero , Kerstin Falk , Guido Ori

Within the framework of a discrete Gaussian model, we present analytical results for the interaction induced by a lamellar phase between small embedded colloids. We consider the two limits of particles strongly adherent to the adjacent…

We propose and investigate a model for lipid raft formation and dynamics in biological membranes. The model describes the lipid composition of the membrane and an interaction with cholesterol. To account for cholesterol exchange between…

Analysis of PDEs · Mathematics 2016-03-15 Harald Garcke , Johannes Kampmann , Andreas Rätz , Matthias Röger

In recent years, colorectal cancer has become one of the most significant diseases that endanger human health. Deep learning methods are increasingly important for the classification of colorectal histopathology images. However, existing…

Computer Vision and Pattern Recognition · Computer Science 2022-06-08 Haoyuan Chen , Chen Li , Xiaoyan Li , Md Mamunur Rahaman , Weiming Hu , Yixin Li , Wanli Liu , Changhao Sun , Hongzan Sun , Xinyu Huang , Marcin Grzegorzek

Cationic lipid membranes are known to form compact complexes with DNA and to be effective as gene delivery agents both in vitro and in vivo. Here we employ molecular dynamics simulations for a detailed atomistic study of lipid bilayers…

Soft Condensed Matter · Physics 2009-11-10 A. A. Gurtovenko , Michael Patra , Mikko Karttunen , Ilpo Vattulainen

Colloidal particles disturb the alignment of rod-like molecules of liquid crystals, giving rise to long-range interactions that minimize the free energy of distorted regions. Particle shape and topology are known to guide this self-assembly…

Soft Condensed Matter · Physics 2017-12-29 Ye Yuan , Angel Martinez , Bohdan Senyuk , Mykola Tasinkevych , Ivan I. Smalyukh

Hydrophobic thickness mismatch between integral membrane proteins and the surrounding lipid bilayer can produce lipid bilayer thickness deformations. Experiment and theory have shown that protein-induced lipid bilayer thickness deformations…

Biomolecules · Quantitative Biology 2016-11-04 Osman Kahraman , Peter D. Koch , William S. Klug , Christoph A. Haselwandter

The utility of non functionalized poly(N-isopropylacrylamide) (pNIPAM) microgels in physiological and environmental applications is strictly dependent on their reversible thermoresponsiveness and stability in saline media. Despite their…

Soft Condensed Matter · Physics 2026-03-31 Syamjith KS , Alan Ranjit Jacob

Self-assembly of polymers at liquid interfaces using non-covalent interactions has emerged as a promising technique to reversibly produce self-healing membranes. Besides the assembly process, it is also crucial to control the mechanical…

Relatively short peptides, such as toxins and antimicrobial-peptides, are known to insert themselves into cell membranes. On the basis of simple bead-spring models for the membrane lipids, the peptide, and water, detailed processes of the…

Soft Condensed Matter · Physics 2007-05-23 Mitsuharu Okazaki , Tomoki Watanabe , Naohito Urakami , Takashi Yamamoto

We study, using dissipative particle dynamics simulations, the effect of active lipid flip-flop on model fluid bilayer membranes. We consider both cases of symmetric as well as asymmetric flip-flops. Symmetric flip-flop leads to a steady…

Soft Condensed Matter · Physics 2009-11-13 Sanoop Ramachandran , P. B. Sunil Kumar , Mohamed Laradji
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