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The spatio-temporal organization of proteins and the associated morphological changes in membranes are of importance in cell signaling. Several mechanisms that promote the aggregation of proteins at low cell surface concentrations have been…

Biological Physics · Physics 2018-04-18 K. K. Sreeja , P. B. Sunil Kumar

We use a lattice model of a ternary mixture containing saturated and unsaturated lipids with cholesterol (Chol), to study the structural properties characterizing the coexistence between the liquid-disordered and liquid-ordered phases.…

Soft Condensed Matter · Physics 2023-10-24 Tanmoy Sarkar , Oded Farago

Though 1-alkanols are well known to have anesthetic properties, the mode of operation remains enigmatic. We perform extensive atomistic molecular dynamics simulation to study the partitioning of 1- alkanols of different chain-lengths in…

Biological Physics · Physics 2018-06-07 Anirban Polley

A variety of models for the membrane-mediated interaction of particles in lipid membranes, mostly well-established in theoretical physics, is reviewed from a mathematical perspective. We provide mathematically consistent formulations in a…

Analysis of PDEs · Mathematics 2016-06-29 Charles M. Elliott , Carsten Gräser , Graham Hobbs , Ralf Kornhuber , Maren-Wanda Wolf

Many of the processes that underly neural computation are carried out by ion channels embedded in the plasma membrane, a two-dimensional liquid that surrounds all cells. Recent experiments have demonstrated that this membrane is poised…

Biological Physics · Physics 2016-07-26 Ofer Kimchi , Sarah L. Veatch , Benjamin B. Machta

Rafts, or functional domains, are transient nano- or mesoscopic structures in the plasma membrane and are thought to be essential for many cellular processes such as signal transduction, adhesion, trafficking and lipid/protein sorting.…

A capacitor consisting of the [bmim][NTf$_2$] ionic liquid (IL) confined in between planar graphite electrodes has been investigated by molecular dynamics based on an all-atom, unpolarizable force field. Despite a few peculiarities due to…

Effects of the mismatch between the hydrophobic length, d, of transmembrane alpha helices of integral proteins and the hydrophobic thickness, D_h, of the membranes they span are studied theoretically utilizing a microscopic model of lipids.…

Soft Condensed Matter · Physics 2009-11-07 Daniel Duque , Xiao-jun Li , Kirill Katsov , Michael Schick

To better understand lipid membranes in living organisms, the study of intermolecular forces using the osmotic pressure technique applied to model lipid membranes has constituted the ground knowledge in the field of biophysics since four…

Soft Condensed Matter · Physics 2020-02-26 Niki Baccile , Viviana Cristiglio

Interfacial hydration structures are crucial in wide-ranging applications, including battery, colloid, lubrication etc. Multivalent ions like Mg2+ and La3+ show irreplaceable roles in these applications, which are hypothesized due to their…

Chemical Physics · Physics 2024-06-28 Han Li , Zhi Xu , Jiacheng Li , Alessandro Siria , Ming Ma

Understanding interactions between membranes requires measurements on well-controlled systems close to natural conditions, in which fluctuations play an important role. We have determined, by grazing incidence X-ray scattering, the…

It is known that lipid membranes become permeable in their melting regime. In microscopic conductance measurements on black lipid membranes one finds that conduction takes place via quantized events closely resembling those reported for…

Biological Physics · Physics 2010-06-17 Katarzyna Wodzinska , Andreas Blicher , Thomas Heimburg

One of the main roles of the lipid layer (LL) of the tear film (TF) is to help prevent evaporation of the aqueous layer (AL). The LL thickness, composition, and structure all contribute to its barrier function. It is believed that the lipid…

Fluid Dynamics · Physics 2024-04-29 M. J. Taranchuk , R. J. Braun

We derive a multiphysics model that accounts for network elasticity with spontaneous strains, swelling and nematic interactions in liquid crystal gels (LCGs). We discuss the coupling among the various physical mechanisms, with particular…

Soft Condensed Matter · Physics 2018-11-28 Alessandro Lucantonio , Antonio DeSimone

The influence of the molecular structure of the nematic liquid crystal (NLC) on the photoalignment process at the NLC -- polymer interface has been investigated experimentally. NLCs having exclusively phenyl-, or cyclohexane rings in the…

Soft Condensed Matter · Physics 2020-04-01 Ameer R. K. Nassrah , István Jánossy , Tibor Tóth-Katona

By reinforcing the interaction energy of the liquid with respect to the surface using total wetting boundary conditions, the response of liquids to mechanical shear stress is stronger and exhibits at sub-millimeter scale elastic properties.…

Soft Condensed Matter · Physics 2022-07-29 Eni Kume , Peter Dunne , Nicolas Martin , Patrick Baroni , Laurence Noirez

In processes such as embryo shaping, wound healing, and malignant cell invasion, epithelial cells transition between dispersed phases, where the cells move independently, and condensed phases, where they aggregate and deform to close gaps,…

Soft Condensed Matter · Physics 2024-09-25 Anshuman Pasupalak , Zeng Wu , Massimo Pica Ciamarra

There is mounting evidence that lipid bilayers display conductive properties. However, when interpreting the electrical response of biological membranes to voltage changes, they are commonly considered as inert insulators. However, lipid…

Biological Physics · Physics 2022-11-24 Karis A. Zecchi , Thomas Heimburg

Membrane proteins serve a wide range of vital roles in the functioning of living organisms. Compared to other classes of proteins, determining membrane protein structures remains a challenge, in large part due to the difficulty in…

The phase separation in lipid bilayers that include negatively charged lipids is examined experimentally. We observed phase-separated structures and determined the membrane miscibility temperatures in several binary and ternary lipid…

Soft Condensed Matter · Physics 2014-10-16 Hiroki Himeno , Naofumi Shimokawa , Shigeyuki Komura , David Andelman , Tsutomu Hamada , Masahiro Takagi