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Meta-analysis, because of both logistical convenience and statistical efficiency, is widely popular for synthesizing information on common parameters of interest across multiple studies. We propose developing a generalized meta-analysis…

Methodology · Statistics 2018-11-27 Prosenjit Kundu , Runlong Tang , Nilanjan Chatterjee

Recent results suggest that reinitializing a subset of the parameters of a neural network during training can improve generalization, particularly for small training sets. We study the impact of different reinitialization methods in several…

Machine Learning · Computer Science 2021-09-02 Ibrahim Alabdulmohsin , Hartmut Maennel , Daniel Keysers

Iterative regularization is a classic idea in regularization theory, that has recently become popular in machine learning. On the one hand, it allows to design efficient algorithms controlling at the same time numerical and statistical…

Machine Learning · Statistics 2024-10-10 Vassilis Apidopoulos , Tomaso Poggio , Lorenzo Rosasco , Silvia Villa

Reward hacking -- where RL agents exploit gaps in misspecified reward functions -- has been widely observed, but not yet systematically studied. To understand how reward hacking arises, we construct four RL environments with misspecified…

Machine Learning · Computer Science 2022-02-15 Alexander Pan , Kush Bhatia , Jacob Steinhardt

The primary goal of randomized trials is to compare the effects of different interventions on some outcome of interest. In addition to the treatment assignment and outcome, data on baseline covariates, such as demographic characteristics or…

Applications · Statistics 2014-01-09 Alisa J. Stephens , Eric J. Tchetgen Tchetgen , Victor De Gruttola

Convergence results for averages of independent replications of counting processes are established in a $p$-variation setting and under certain assumptions. Such convergence results can be combined with functional differentiability results…

Probability · Mathematics 2019-03-12 Morten Overgaard

Uncertainty quantification is vital for decision-making and risk assessment in machine learning. Mean-variance regression models, which predict both a mean and residual noise for each data point, provide a simple approach to uncertainty…

Machine Learning · Statistics 2025-12-01 Eliot Wong-Toi , Alex Boyd , Vincent Fortuin , Stephan Mandt

We study average treatment effect (ATE) estimation under complete randomization with many covariates in a design-based, finite-population framework. In randomized experiments, regression adjustment can improve precision of estimators using…

Statistics Theory · Mathematics 2025-11-12 Dogyoon Song

Covariate adjustment is an approach to improve the precision of trial analyses by adjusting for baseline variables that are prognostic of the primary endpoint. Motivated by the SEARCH Universal HIV Test-and-Treat Trial (2013-2017), we tell…

Methodology · Statistics 2025-12-16 Laura B. Balzer , Mark J. van der Laan , Maya L. Petersen

Covariate-adjusted randomization (CAR) can reduce the risk of covariate imbalance and, when accounted for in analysis, increase the power of a trial. Despite CAR advances, stratified randomization remains the most common CAR method. Matched…

Methodology · Statistics 2023-07-13 Jonathan J. Chipman , Lindsay Mayberry , Robert A. Greevy

Objective: The use of routinely-acquired medical data for research purposes requires the protection of patient confidentiality via data anonymisation. The objective of this work is to calculate the risk of re-identification arising from a…

Machine Learning · Computer Science 2022-04-01 Anna Antoniou , Giacomo Dossena , Julia MacMillan , Steven Hamblin , David Clifton , Paula Petrone

We use p-values as a discrepancy criterion for identifying the threshold value at which a regression function takes off from its baseline value -- a problem that is motivated by applications in omics experiments, systems engineering,…

Methodology · Statistics 2010-08-26 Bodhisattva Sen , Moulinath Banerjee , George Michialidis

It is common to conduct causal inference in matched observational studies by proceeding as though treatment assignments within matched sets are assigned uniformly at random and using this distribution as the basis for inference. This…

Methodology · Statistics 2023-11-14 Samuel D. Pimentel , Yaxuan Huang

We introduce style augmentation, a new form of data augmentation based on random style transfer, for improving the robustness of convolutional neural networks (CNN) over both classification and regression based tasks. During training, our…

Computer Vision and Pattern Recognition · Computer Science 2019-04-15 Philip T. Jackson , Amir Atapour-Abarghouei , Stephen Bonner , Toby Breckon , Boguslaw Obara

Heterogeneity is a hallmark of complex diseases. Regression-based heterogeneity analysis, which is directly concerned with outcome-feature relationships, has led to a deeper understanding of disease biology. Such an analysis identifies the…

Methodology · Statistics 2022-11-29 Ziye Luo , Xinyue Yao , Yifan Sun , Xinyan Fan

Covariate adjustment can improve precision in analyzing randomized experiments. With fully observed data, regression adjustment and propensity score weighting are asymptotically equivalent in improving efficiency over unadjusted analysis.…

Methodology · Statistics 2024-03-06 Anqi Zhao , Peng Ding , Fan Li

This paper proposes a versatile covariate adjustment method that directly incorporates covariate balance in regression discontinuity (RD) designs. The new empirical entropy balancing method reweights the standard local polynomial RD…

Econometrics · Economics 2024-05-29 Jun Ma , Zhengfei Yu

Linear regression is arguably the most fundamental statistical model; however, the validity of its use in randomized clinical trials, despite being common practice, has never been crystal clear, particularly when stratified or…

Methodology · Statistics 2023-02-14 Wei Ma , Fuyi Tu , Hanzhong Liu

Clinical research should conform to high standards of ethical and scientific integrity, given that human lives are at stake. However, economic incentives can generate conflicts of interest for investigators, who may be inclined to withhold…

General Economics · Economics 2022-10-12 Jérôme Adda , Christian Decker , Marco Ottaviani

In spam and malware detection, attackers exploit randomization to obfuscate malicious data and increase their chances of evading detection at test time; e.g., malware code is typically obfuscated using random strings or byte sequences to…

Machine Learning · Computer Science 2016-09-07 Samuel Rota Bulò , Battista Biggio , Ignazio Pillai , Marcello Pelillo , Fabio Roli