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Depression is one of the most prevalent and debilitating mental health conditions worldwide, frequently underdiagnosed and undertreated. The proliferation of social media platforms provides a rich source of naturalistic linguistic signals…

Computation and Language · Computer Science 2026-04-23 Giorgia Gulino , Manuel Petrucci

Depression has affected millions of people worldwide and has become one of the most common mental disorders. Early mental disorder detection can reduce costs for public health agencies and prevent other major comorbidities. Additionally,…

Computation and Language · Computer Science 2024-04-09 Giuliano Lorenzoni , Cristina Tavares , Nathalia Nascimento , Paulo Alencar , Donald Cowan

Accurate and interpretable detection of depressive language in social media is useful for early interventions of mental health conditions, and has important implications for both clinical practice and broader public health efforts. In this…

Computation and Language · Computer Science 2025-06-10 Samuel Kim , Oghenemaro Imieye , Yunting Yin

Major depressive disorder is a debilitating disease affecting 264 million people worldwide. While many antidepressant medications are available, few clinical guidelines support choosing among them. Decision support tools (DSTs) embodying…

Anxiety and depression are the most common mental health issues worldwide, affecting a non-negligible part of the population. Accordingly, stakeholders, including governments' health systems, are developing new strategies to promote early…

Artificial Intelligence · Computer Science 2024-12-24 Francisco de Arriba-Pérez , Silvia García-Méndez

We aim to evaluate the efficacy of traditional machine learning and large language models (LLMs) in classifying anxiety and depression from long conversational transcripts. We fine-tune both established transformer models (BERT, RoBERTa,…

Computation and Language · Computer Science 2024-07-19 Junwei Sun , Siqi Ma , Yiran Fan , Peter Washington

Mental health disorders represent a burgeoning global public health challenge. While Large Language Models (LLMs) have demonstrated potential in psychiatric assessment, their clinical utility is severely constrained by benchmarks that lack…

Artificial Intelligence · Computer Science 2026-02-04 Xiao Sun , Yuming Yang , Junnan Zhu , Jiang Zhong , Xinyu Zhou , Kaiwen Wei

Simulating collective decision-making involves more than aggregating individual behaviors; it emerges from dynamic interactions among individuals. While large language models (LLMs) offer strong potential for social simulation, achieving…

Multiagent Systems · Computer Science 2025-07-11 Qirui Mi , Mengyue Yang , Xiangning Yu , Zhiyu Zhao , Cheng Deng , Bo An , Haifeng Zhang , Xu Chen , Jun Wang

Depression remains widely underdiagnosed and undertreated because stigma and subjective symptom ratings hinder reliable screening. To address this challenge, we propose a coarse-to-fine, multi-stage framework that leverages large language…

Artificial Intelligence · Computer Science 2026-04-14 Shiyu Teng , Jiaqing Liu , Hao Sun , Yu Li , Shurong Chai , Ruibo Hou , Tomoko Tateyama , Lanfen Lin , Yen-Wei Chen

Subjective well-being is a key metric in economic, medical, and policy decision-making. As artificial intelligence provides scalable tools for modelling human outcomes, it is crucial to evaluate whether large language models (LLMs) can…

Human-Computer Interaction · Computer Science 2025-07-09 Pat Pataranutaporn , Nattavudh Powdthavee , Chayapatr Archiwaranguprok , Pattie Maes

Adult neurodivergence, including Attention-Deficit/Hyperactivity Disorder (ADHD), high-functioning Autism Spectrum Disorder (ASD), and Cognitive Disengagement Syndrome (CDS), is marked by substantial symptom overlap that limits the…

Neurons and Cognition · Quantitative Biology 2026-01-23 Francesco Chiappone , Davide Marocco , Nicola Milano

Major depressive disorder (MDD) is a prevalent mental disorder associated with complex neurobiological changes that cannot be fully captured using a single imaging modality. The use of multimodal magnetic resonance imaging (MRI) provides a…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Nojod M. Alotaibi , Areej M. Alhothali

In diagnosing challenging conditions such as Alzheimer's disease (AD), imaging is an important reference. Non-imaging patient data such as patient information, genetic data, medication information, cognitive and memory tests also play a…

Machine Learning · Computer Science 2023-06-01 Yingjie Feng , Jun Wang , Xianfeng Gu , Xiaoyin Xu , Min Zhang

Automatic disease diagnosis has become increasingly valuable in clinical practice. The advent of large language models (LLMs) has catalyzed a paradigm shift in artificial intelligence, with growing evidence supporting the efficacy of LLMs…

Large language models (LLMs) have emerged as powerful tools for medical information retrieval, yet their accuracy and depth remain limited in specialized domains such as Alzheimer's disease (AD), a growing global health challenge. To…

Large-scale collaborative analysis of brain imaging data, in psychiatry and neu-rology, offers a new source of statistical power to discover features that boost ac-curacy in disease classification, differential diagnosis, and outcome…

Substance use disorder (SUD) poses a major concern due to its detrimental effects on health and society. SUD identification and treatment depend on a variety of factors such as severity, co-determinants (e.g., withdrawal symptoms), and…

Computation and Language · Computer Science 2024-03-20 Maria Mahbub , Gregory M. Dams , Sudarshan Srinivasan , Caitlin Rizy , Ioana Danciu , Jodie Trafton , Kathryn Knight

The development of large language models (LLMs) has brought unprecedented possibilities for artificial intelligence (AI) based medical diagnosis. However, the application perspective of LLMs in real diagnostic scenarios is still unclear…

Computation and Language · Computer Science 2024-05-21 Zhoujian Sun , Cheng Luo , Ziyi Liu , Zhengxing Huang

Mental disorders are clinically significant patterns of behavior that are associated with stress and/or impairment in social, occupational, or family activities. People suffering from such disorders are often misjudged and poorly diagnosed…

Machine Learning · Computer Science 2025-09-03 Abu Shad Ahammed , Sayeri Mukherjee , Roman Obermaisser

The rapid advancement of deep learning (DL) has transformed healthcare, particularly in cancer detection and diagnosis. DL surpasses traditional machine learning and human accuracy, making it a critical tool for identifying diseases.…

Image and Video Processing · Electrical Eng. & Systems 2025-04-21 Yassine Habchi , Hamza Kheddar , Yassine Himeur , Adel Belouchrani , Erchin Serpedin , Fouad Khelifi , Muhammad E. H. Chowdhury