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Multimodal large language models (MLLMs) have shown remarkable potential in various domains, yet their application in the medical field is hindered by several challenges. General-purpose MLLMs often lack the specialized knowledge required…

Artificial Intelligence · Computer Science 2025-09-29 Guanghao Zhu , Zhitian Hou , Zeyu Liu , Zhijie Sang , Congkai Xie , Hongxia Yang

Despite the promise of foundation models in medical AI, current systems remain limited - they are modality-specific and lack transparent reasoning processes, hindering clinical adoption. To address this gap, we present EVLF-FM, a multimodal…

Medical image grounding aims to align natural language phrases with specific regions in medical images, serving as a foundational task for intelligent diagnosis, visual question answering (VQA), and automated report generation (MRG).…

Computer Vision and Pattern Recognition · Computer Science 2025-11-07 Ziye Deng , Ruihan He , Jiaxiang Liu , Yuan Wang , Zijie Meng , Songtao Jiang , Yong Xie , Zuozhu Liu

Artificial Intelligence (AI) has the potential to revolutionize diagnosis and segmentation in medical imaging. However, development and clinical implementation face multiple challenges including limited data availability, lack of…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Zelong Liu , Andrew Tieu , Nikhil Patel , Georgios Soultanidis , Louisa Deyer , Ying Wang , Sean Huver , Alexander Zhou , Yunhao Mei , Zahi A. Fayad , Timothy Deyer , Xueyan Mei

Retinal foundation models aim to learn generalizable representations from diverse retinal images, facilitating label-efficient model adaptation across various ophthalmic tasks. Despite their success, current retinal foundation models are…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Kai Yu , Yang Zhou , Yang Bai , Zhi Da Soh , Xinxing Xu , Rick Siow Mong Goh , Ching-Yu Cheng , Yong Liu

Background: Chromosome karyotype analysis is crucial for diagnosing hereditary diseases, yet detecting structural abnormalities remains challenging. While AI has shown promise in medical imaging, its effectiveness varies across modalities.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Ran Wei , ZhiXiong Lan , Qing Yan , Ning Song , Ming Lv , LongQing Ye

We present UniModel, a unified generative model that jointly supports visual understanding and visual generation within a single pixel-to-pixel diffusion framework. Our goal is to achieve unification along three axes: the model, the tasks,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Chi Zhang , Jiepeng Wang , Youming Wang , Yuanzhi Liang , Xiaoyan Yang , Zuoxin Li , Haibin Huang , Xuelong Li

Unified multimodal models provide a natural and promising architecture for understanding diverse and complex real-world knowledge while generating high-quality images. However, they still rely primarily on frozen parametric knowledge, which…

Medical imaging provides critical evidence for clinical diagnosis, treatment planning, and surgical decisions, yet most existing imaging models are narrowly focused and require multiple specialized networks, limiting their generalization.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Guoxin Wang , Jun Zhao , Xinyi Liu , Yanbo Liu , Xuyang Cao , Chao Li , Zhuoyun Liu , Qintian Sun , Fangru Zhou , Haoqiang Xing , Zhenhong Yang

Identifying specific anatomical structures (\textit{e.g.}, lesions or landmarks) in medical images plays a fundamental role in medical image analysis. Exemplar-based landmark detection methods are receiving increasing attention since they…

Computer Vision and Pattern Recognition · Computer Science 2024-01-19 Xiaoyu Bai , Fan Bai , Xiaofei Huo , Jia Ge , Jingjing Lu , Xianghua Ye , Ke Yan , Yong Xia

Machine learning models for medical images can help physicians diagnose and manage diseases. However, due to the fact that medical image annotation requires a great deal of manpower and expertise, as well as the fact that clinical…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Can Li , Sheng Shao , Junyi Qu , Shuchao Pang , Mehmet A. Orgun

Ultrasound imaging is widely used in clinical diagnosis due to its non-invasive nature and real-time capabilities. However, traditional ultrasound diagnostics relies heavily on physician expertise and is often hampered by suboptimal image…

Image and Video Processing · Electrical Eng. & Systems 2025-12-18 Yuncheng Jiang , Chun-Mei Feng , Jinke Ren , Jun Wei , Zixun Zhang , Yiwen Hu , Yunbi Liu , Rui Sun , Xuemei Tang , Juan Du , Xiang Wan , Yong Xu , Bo Du , Xin Gao , Guangyu Wang , Shaohua Zhou , Shuguang Cui , Zhen Li

Universal visual anomaly detection (AD) aims to identify anomaly images and segment anomaly regions towards open and dynamic scenarios, following zero- and few-shot paradigms without any dataset-specific fine-tuning. We have witnessed…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Bin-Bin Gao , Chengjie Wang

Pathology image analysis plays a pivotal role in medical diagnosis, with deep learning techniques significantly advancing diagnostic accuracy and research. While numerous studies have been conducted to address specific pathological tasks,…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Dankai Liao , Sicheng Chen , Nuwa Xi , Qiaochu Xue , Jieyu Li , Lingxuan Hou , Zeyu Liu , Chang Han Low , Yufeng Wu , Yiling Liu , Yanqin Jiang , Dandan Li , Shangqing Lyu

From self-supervised, vision-only models to contrastive visual-language frameworks, computational pathology has rapidly evolved in recent years. Generative AI "co-pilots" now demonstrate the ability to mine subtle, sub-visual tissue cues…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Mohsin Bilal , Aadam , Manahil Raza , Youssef Altherwy , Anas Alsuhaibani , Abdulrahman Abduljabbar , Fahdah Almarshad , Paul Golding , Nasir Rajpoot

Rapid advancements in foundation models, including Large Language Models, Vision-Language Models, Multimodal Large Language Models, and Vision-Language-Action Models, have opened new avenues for embodied AI in mobile service robotics. By…

Robotics · Computer Science 2026-03-11 Matthew Lisondra , Beno Benhabib , Goldie Nejat

Foundation models have emerged as a powerful paradigm in computational pathology (CPath), enabling scalable and generalizable analysis of histopathological images. While early developments centered on uni-modal models trained solely on…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Xiaohui Chen , Yi He , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Multimodal foundation models have shown compelling but conflicting performance in medical image interpretation. However, the mechanisms by which these models integrate and prioritize different data modalities, including images and text,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Thomas Buckley , James A. Diao , Pranav Rajpurkar , Adam Rodman , Arjun K. Manrai

Foundational Models (FMs) are gaining increasing attention in the biomedical AI ecosystem due to their ability to represent and contextualize multimodal biomedical data. These capabilities make FMs a valuable tool for a variety of tasks,…

Medicine is inherently multimodal, with rich data modalities spanning text, imaging, genomics, and more. Generalist biomedical artificial intelligence (AI) systems that flexibly encode, integrate, and interpret this data at scale can…