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Electroanatomic mapping as routinely acquired in ablation therapy of ventricular tachycardia is the gold standard method to identify the arrhythmogenic substrate. To reduce the acquisition time and still provide maps with high spatial…

Numerical simulation of multi-phase fluid dynamics in porous media is critical for many energy and environmental applications in Earth's subsurface. Data-driven surrogate modeling provides computationally inexpensive alternatives to…

Computational Physics · Physics 2024-04-16 Jiamin Jiang , Bo Guo

Patient-specific computational modeling has emerged as a powerful tool for surgical planning in complex congenital heart disease. One promising application is complex biventricular repair, which often requires construction of a custom…

Computational Engineering, Finance, and Science · Computer Science 2026-03-27 Elena Sabdy Martinez , Alexander D. Kaiser , Alexander K. Reed , Sascha W. Stocker , Amit Sharir , Perry S. Choi , Shiraz A. Maskatia , Michael R. Ma , Alison Lesly Marsden

Agent-based modeling (ABM) is a powerful computational approach for studying complex biological and biomedical systems, yet its widespread use remains limited by significant computational demands. As models become increasingly…

Quantitative Methods · Quantitative Biology 2025-04-17 Kerri-Ann Norton , Daniel Bergman , Harsh Vardhan Jain , Trachette Jackson

Optimizing the locations of multiple CO2 injection wells will be essential as we proceed from demonstration-scale to large-scale carbon storage operations. Well placement optimization is, however, a computationally intensive task because…

Computational Engineering, Finance, and Science · Computer Science 2024-10-10 Haoyu Tang , Louis J. Durlofsky

Real-world settings often do not allow acquisition of high-resolution volumetric images for accurate morphological assessment and diagnostic. In clinical practice it is frequently common to acquire only sparse data (e.g. individual slices)…

Image and Video Processing · Electrical Eng. & Systems 2019-08-30 Benjamin Hou , Athanasios Vlontzos , Amir Alansary , Daniel Rueckert , Bernhard Kainz

Simulating the mechanical response of advanced materials can be done more accurately using concurrent multiscale models than with single-scale simulations. However, the computational costs stand in the way of the practical application of…

Machine Learning · Computer Science 2024-02-21 J. Storm , I. B. C. M. Rocha , F. P. van der Meer

Multi-omics data offer unprecedented insights into complex biological systems, yet their high dimensionality, sparsity, and intricate interactions pose significant analytical challenges. Network-based approaches have advanced multi-omics…

Large prospective epidemiological studies acquire cardiovascular magnetic resonance (CMR) images for pre-symptomatic populations and follow these over time. To support this approach, fully automatic large-scale 3D analysis is essential. In…

Image and Video Processing · Electrical Eng. & Systems 2019-07-04 Rahman Attar , Marco Pereanez , Christopher Bowles , Stefan K. Piechnik , Stefan Neubauer , Steffen E. Petersen , Alejandro F. Frangi

Computational Fluid Dynamics (CFD) is used to assist in designing artificial valves and planning procedures, focusing on local flow features. However, assessing the impact on overall cardiovascular function or predicting longer-term…

Supervised deep learning methods typically rely on large datasets for training. Ethical and practical considerations usually make it difficult to access large amounts of healthcare data, such as medical images, with known task-specific…

Medical Physics · Physics 2023-05-26 Marta Varela , Anil A Bharath

Patient-specific computational models of the heart are powerful tools for cardiovascular research and medicine, with demonstrated applications in treatment planning, device evaluation, and surgical decision-making. Yet constructing such…

Medical Physics · Physics 2026-04-21 Aaron L. Brown , Ju Liu , Daniel B. Ennis , Alison L. Marsden

We propose a novel algorithm to recover fetal electrocardiogram (ECG) for both the fetal heart rate analysis and morphological analysis of its waveform from two or three trans-abdominal maternal ECG channels. We design an algorithm based on…

Signal Processing · Electrical Eng. & Systems 2019-08-09 Pei-Chun Su , Stephen Miller , Salim Idriss , Piers Barker , Hau-Tieng Wu

Whole-brain parcellation from MRI is a critical yet challenging task due to the complexity of subdividing the brain into numerous small, irregular shaped regions. Traditionally, template-registration methods were used, but recent advances…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Yucheng Li , Xiaofan Wang , Junyi Wang , Yijie Li , Xi Zhu , Mubai Du , Dian Sheng , Wei Zhang , Fan Zhang

Surrogate models provide fast alternatives to costly aerodynamic simulations and are extremely useful in design and optimization applications. This study proposes the use of a recent kernel-based neural surrogate, KHRONOS. In this work, we…

Machine Learning · Computer Science 2025-12-12 Apurba Sarker , Reza T. Batley , Darshan Sarojini , Sourav Saha

While ventricular electromechanics is extensively studied, four-chamber heart models have only been addressed recently; most of these works however neglect atrial contraction. Indeed, as atria are characterized by a complex physiology…

High-performance scientific simulations, important for comprehension of complex systems, encounter computational challenges especially when exploring extensive parameter spaces. There has been an increasing interest in developing deep…

Machine Learning · Computer Science 2024-07-15 Pradeep Bajracharya , Javier Quetzalcóatl Toledo-Marín , Geoffrey Fox , Shantenu Jha , Linwei Wang

Medical imaging refers to the technologies and methods utilized to view the human body and its inside, in order to diagnose, monitor, or even treat medical disorders. This paper aims to explore the application of deep learning techniques in…

Image and Video Processing · Electrical Eng. & Systems 2024-11-08 Ketan Suhaas Saichandran

The ability to map left ventricle (LV) myocardial motion using computed tomography angiography (CTA) is essential to diagnosing cardiovascular conditions and guiding interventional procedures. Due to their inherent locality, conventional…

Image and Video Processing · Electrical Eng. & Systems 2024-11-08 Shahar Zuler , Shai Tejman-Yarden , Dan Raviv

Deep learning methods exhibit promising performance for predictive modeling in healthcare, but two important challenges remain: -Data insufficiency:Often in healthcare predictive modeling, the sample size is insufficient for deep learning…

Machine Learning · Computer Science 2017-04-04 Edward Choi , Mohammad Taha Bahadori , Le Song , Walter F. Stewart , Jimeng Sun
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