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Data driven approaches have the potential to make modeling complex, nonlinear physical phenomena significantly more computationally tractable. For example, computational modeling of fracture is a core challenge where machine learning…

Machine Learning · Computer Science 2025-10-01 Erfan Hamdi , Emma Lejeune

The Cellular-Potts model is a powerful and ubiquitous framework for developing computational models for simulating complex multicellular biological systems. Cellular-Potts models (CPMs) are often computationally expensive due to the…

In the context of structural health monitoring (SHM), the selection and extraction of damage-sensitive features from raw sensor recordings represent a critical step towards solving the inverse problem underlying the identification of…

Computational Engineering, Finance, and Science · Computer Science 2025-12-03 Matteo Torzoni , Andrea Manzoni , Stefano Mariani

We present a graph neural network (GNN) based surrogate framework for molecular dynamics simulations that directly predicts atomic displacements and learns the underlying evolution operator of an atomistic system. Unlike conventional…

Materials Science · Physics 2025-12-29 Judah Immanuel , Avik Mahata , Aniruddha Maiti

Computer-based simulations of non-invasive cardiac electrical outputs, such as electrocardiograms and body surface potential maps, usually entail severe computational costs due to the need of capturing fine-scale processes and to the…

Numerical Analysis · Mathematics 2023-08-09 Elena Zappon , Andrea Manzoni , Alfio Quarteroni

We propose GNN-Surrogate, a graph neural network-based surrogate model to explore the parameter space of ocean climate simulations. Parameter space exploration is important for domain scientists to understand the influence of input…

Atmospheric and Oceanic Physics · Physics 2022-02-23 Neng Shi , Jiayi Xu , Skylar W. Wurster , Hanqi Guo , Jonathan Woodring , Luke P. Van Roekel , Han-Wei Shen

Electrocardiograms (ECGs) provide non-invasive measurements of heart activity and are established tools for detecting cardiac arrhythmias. Although supervised machine learning has emerged as a promising approach for automated heartbeat…

Machine Learning · Computer Science 2026-04-27 Amir Reza Vazifeh , Jason W. Fleischer

We consider the problem of constructing surrogate operators for parameter-to-solution maps arising from parametric partial differential equations, where repeated forward model evaluations are computationally expensive. We present a…

Machine Learning · Computer Science 2026-04-02 Josephine Westermann , Benno Huber , Thomas O'Leary-Roseberry , Jakob Zech

Background: Accumulation of abnormal contact stress is a primary biomechanical driver of acute meniscal tears and chronic osteoarthritis. While Finite Element Analysis (FEA) provides the necessary fidelity to quantify these injury-inducing…

Quantitative Methods · Quantitative Biology 2025-12-16 Zhengye Pan , Jianwei Zuo , Jiajia Luo

Aerodynamic optimization is crucial for developing eco-friendly, aerodynamic, and stylish cars, which requires close collaboration between aerodynamicists and stylists, a collaboration impaired by the time-consuming nature of aerodynamic…

Machine Learning · Computer Science 2025-08-05 Sam Jacob Jacob , Markus Mrosek , Carsten Othmer , Harald Köstler

Fully automatic cardiac segmentation can be a fast and reproducible method to extract clinical measurements from an echocardiography examination. The U-Net architecture is the current state-of-the-art deep learning architecture for medical…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Gilles Van De Vyver , Sarina Thomas , Guy Ben-Yosef , Sindre Hellum Olaisen , Håvard Dalen , Lasse Løvstakken , Erik Smistad

Cardiac Magnetic Resonance (CMR) imaging serves as the gold-standard for evaluating cardiac morphology and function. Typically, a multi-view CMR stack, covering short-axis (SA) and 2/3/4-chamber long-axis (LA) views, is acquired for a…

Image and Video Processing · Electrical Eng. & Systems 2025-07-03 Yundi Zhang , Chen Chen , Suprosanna Shit , Sophie Starck , Daniel Rueckert , Jiazhen Pan

Crash simulations play an essential role in improving vehicle safety, design optimization, and injury risk estimation. Unfortunately, numerical solutions of such problems using state-of-the-art high-fidelity models require significant…

Machine Learning · Computer Science 2024-02-16 Jonas Kneifl , Jörg Fehr , Steven L. Brunton , J. Nathan Kutz

Cardiac parametric mapping is useful for evaluating cardiac fibrosis and edema. Parametric mapping relies on single-shot heartbeat-by-heartbeat imaging, which is susceptible to intra-shot motion during the imaging window. However, reducing…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Calder D. Sheagren , Brenden T. Kadota , Jaykumar H. Patel , Mark Chiew , Graham A. Wright

Electrocardiogram (ECG) detection and delineation are key steps for numerous tasks in clinical practice, as ECG is the most performed non-invasive test for assessing cardiac condition. State-of-the-art algorithms employ digital signal…

Machine Learning · Computer Science 2020-05-12 Guillermo Jimenez-Perez , Alejandro Alcaine , Oscar Camara

Reducing the computational time required by high-fidelity, full order models (FOMs) for the solution of problems in cardiac mechanics is crucial to allow the translation of patient-specific simulations into clinical practice. While FOMs,…

Numerical Analysis · Mathematics 2022-02-09 Ludovica Cicci , Stefania Fresca , Andrea Manzoni , Alfio Quarteroni

Reliable multiscale models of thrombosis require platelet-scale fidelity at organ-scale cost, a gap that scientific machine learning has the potential to narrow. We train a DeepONet surrogate on platelet dynamics generated with LAMMPS for…

Fluid Dynamics · Physics 2025-06-26 Marco Laudato

We introduce a multiphysics and geometric multiscale computational model, suitable to describe the hemodynamics of the whole human heart, driven by a four-chamber electromechanical model. We first present a study on the calibration of the…

Numerical Analysis · Mathematics 2024-03-06 Alberto Zingaro , Michele Bucelli , Roberto Piersanti , Francesco Regazzoni , Luca Dede' , Alfio Quarteroni

4D Computed Tomography (4DCT) is widely used for many clinical applications such as radiotherapy treatment planning, PET and ventilation imaging. However, common 4DCT methods reconstruct multiple breath cycles into a single, arbitrary…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Yuliang Huang , Bjoern Eiben , Kris Thielemans , Jamie R. McClelland

Evolutionary algorithms are increasingly recognised as a viable computational approach for the automated optimisation of deep neural networks (DNNs) within artificial intelligence. This method extends to the training of DNNs, an approach…

Neural and Evolutionary Computing · Computer Science 2024-03-29 Fergal Stapleton , Brendan Cody-Kenny , Edgar Galván