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Standard 6 megavolt (MV) radiotherapy is limited by source size and secondary electron range to minimum radiological penumbra widths of ~2-3 mm. This study investigates sharper beams via upright radiotherapy with lower energies and extended…

Medical Physics · Physics 2026-03-10 Lloyd E Kamole Ghomsi , Clinton Gibson , Veng-Jean Heng , Ramish M Ashraf , Lawrie Skinner

Background: Proximal Junctional Failure (PJF) is a post-operative complication in adult spine surgery, often requiring reoperation. Osteotomy is often used in revision surgeries, leading to 34.8% complications. Hence, suboptimal decisions…

Aiming at the latest particle swarm optimization algorithm, this paper proposes an improved Transformer model to improve the accuracy of heart disease prediction and provide a new algorithm idea. We first use three mainstream machine…

Artificial Intelligence · Computer Science 2025-01-08 Jingyuan Yi , Peiyang Yu , Tianyi Huang , Zeqiu Xu

A new Adaptive Neuro Particle Swarm Optimization (ANPSO) combined with a fuzzy inference system for diagnosing disorders is presented in this paper. The main contributions of the novel proposed method can be a global search across the whole…

Neural and Evolutionary Computing · Computer Science 2019-10-31 Majid Masoumi , Mina Rajabi

We characterized the dosimetric properties of a clinical linear accelerator configured to deliver ultra-high dose rate (UHDR) irradiation to mice and cell-culture FLASH radiobiology experiments. UHDR electron beams were controlled by a…

Background: Radiotherapy treatment planning involves solving large-scale optimization problems that are often approximated and solved sub-optimally due to time constraints. Central to these problems is the dose influence matrix which…

Medical Physics · Physics 2024-10-02 Mojtaba Tefagh , Gourav Jhanwar , Masoud Zarepisheh

Verification of patient specific proton stopping powers obtained in the patient treatment position can be used to reduce the distal margins needed in particle beam planning. Proton radiography can be used as a pre-treatment instrument to…

Purpose: VT is a life-threatening arrhythmia commonly treated with catheter ablation; however, some cases remain refractory to conventional treatment. STAR has emerged as a non-invasive option for such patients. While photon-based STAR has…

We investigate the performance tradeoff between \textit{bistatic positioning (BP)} and \textit{monostatic sensing (MS)} in a multi-input multi-output orthogonal frequency division multiplexing scenario. We derive the Cram\'er-Rao bounds…

Signal Processing · Electrical Eng. & Systems 2025-03-05 Yuchen Zhang , Hui Chen , Pinjun Zheng , Boyu Ning , Henk Wymeersch , Tareq Y. Al-Naffouri

Proton therapy is an emerging method in cancer therapy. One of the main developments is to increase the accuracy of the Bragg-peak position calculation, which requires more precise relative stopping power (RSP) measurements. A promising…

Medical Physics · Physics 2026-02-18 Gábor Bíró , Ákos Sudár , Zsófia Jólesz , Gábor Papp , Gergely Gábor Barnaföldi

A split feasibility formulation for the inverse problem of intensity-modulated radiation therapy (IMRT) treatment planning with dose-volume constraints (DVCs) included in the planning algorithm is presented. It involves a new type of…

Medical Physics · Physics 2017-04-26 S. Penfold , R. Zalas , M. Casiraghi , M. Brooke , Y. Censor , R. Schulte

Optimizing the design of spur gears, regarding their mass or failure reduction, leads to reduced costs. The proposed work is aimed at using Particle Swarm Optimization (PSO) to solve single and multiple-objective optimization problems…

Computational Physics · Physics 2024-01-17 Ricardo Fitas , Carlos Fernandes , Carlos Conceição António

Background: The normal tissue sparing effect of ultra-high dose rate irradiation (>40 Gy/s, UHDR), as compared to conventional dose rate (CONV), has attracted significant research interest for FLASH radiotherapy (RT). Accurate, dose rate…

Medical Physics · Physics 2025-07-08 Lixiang Guo , Banghao Zhou , Yi-Chun Tsai , Kai Jiang , Viktor Iakovenko , Ken Kang-Hsin Wang

Proton FLASH therapy leverages ultra-high dose-rate radiation to enhance the sparing of organs at risk without compromising tumor control probability. To prepare for the delivery of high doses to targets, we aim to develop a deep…

Carbon ion therapy is one of the most advanced forms of radiotherapy, promising improved efficacy against resistant cancers. However, the high precision offered by the carbon ion Bragg peak requires precise knowledge of the beam range…

FLASH radiotherapy (FLASH-RT) achieves tumor control comparable to conventional dose-rate irradiation (CONV-RT) while significantly reducing radiation damage to normal tissues. However, the physical conditions triggering the FLASH sparing…

Commercial treatment planning systems for electron FLASH radiotherapy are unavailable, and the dosimetric precision required for ultra-high dose rate delivery makes Monte Carlo (MC) simulation the gold standard approach. This work…

This paper investigates the controller optimization for a helicopter system with three degrees of freedom (3-DOF). To control the system, we combined fuzzy logic with adaptive control theory. The system is extensively nonlinear and highly…

Robotics · Computer Science 2022-05-03 Shokoufeh Naderi , Maude J. Blondin , Behrooz Rezaie

Simultaneously transmitting and reflecting reconfigurable intelligent surfaces (STAR-RISs) is a promising passive device that contributes to a full-space coverage via transmitting and reflecting the incident signal simultaneously. As a new…

Information Theory · Computer Science 2023-07-25 Xinyu Gao , Wenqiang Yi , Yuanwei Liu , Jianhua Zhang , Ping Zhang

Robust optimization is a commonly employed method to mitigate uncertainties in the planning of intensity-modulated proton therapy (IMPT). In certain contexts, the large number of uncertainty scenarios makes the robust problem impractically…

Medical Physics · Physics 2025-04-22 Ivar Bengtsson
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