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Synthetic healthcare data generation offers a promising solution to research limitations in clinical settings caused by privacy and regulatory constraints. However, current synthetic data generation approaches require specialized knowledge…

Machine Learning · Computer Science 2026-02-19 Nitish Nagesh , Salar Shakibhamedan , Mahdi Bagheri , Ziyu Wang , Nima TaheriNejad , Axel Jantsch , Amir M. Rahmani

The success of AI models relies on the availability of large, diverse, and high-quality datasets, which can be challenging to obtain due to data scarcity, privacy concerns, and high costs. Synthetic data has emerged as a promising solution…

Computation and Language · Computer Science 2024-08-13 Ruibo Liu , Jerry Wei , Fangyu Liu , Chenglei Si , Yanzhe Zhang , Jinmeng Rao , Steven Zheng , Daiyi Peng , Diyi Yang , Denny Zhou , Andrew M. Dai

While data sharing is crucial for knowledge development, privacy concerns and strict regulation (e.g., European General Data Protection Regulation (GDPR)) unfortunately limit its full effectiveness. Synthetic tabular data emerges as an…

Machine Learning · Computer Science 2021-06-02 Zilong Zhao , Aditya Kunar , Hiek Van der Scheer , Robert Birke , Lydia Y. Chen

Although interest in synthetic medical data (SMD) for training and testing AI methods is growing, the absence of a standardized framework to evaluate its quality and applicability hinders its wider adoption. Here, we outline an evaluation…

Artificial Intelligence · Computer Science 2024-12-05 Ghada Zamzmi , Adarsh Subbaswamy , Elena Sizikova , Edward Margerrison , Jana Delfino , Aldo Badano

Ensuring the generalisability of clinical machine learning (ML) models across diverse healthcare settings remains a significant challenge due to variability in patient demographics, disease prevalence, and institutional practices. Existing…

Machine Learning · Computer Science 2025-04-30 Bradley Segal , Joshua Fieggen , David Clifton , Lei Clifton

Privacy, data quality, and data sharing concerns pose a key limitation for tabular data applications. While generating synthetic data resembling the original distribution addresses some of these issues, most applications would benefit from…

Machine Learning · Computer Science 2024-06-04 Mark Vero , Mislav Balunović , Martin Vechev

Differentially private (DP) tabular data synthesis generates artificial data that preserves the statistical properties of private data while safeguarding individual privacy. The emergence of diverse algorithms in recent years has introduced…

Cryptography and Security · Computer Science 2025-11-19 Kai Chen , Xiaochen Li , Chen Gong , Ryan McKenna , Tianhao Wang

This paper provides a detailed survey of synthetic data techniques. We first discuss the expected goals of using synthetic data in data augmentation, which can be divided into four parts: 1) Improving Diversity, 2) Data Balancing, 3)…

Machine Learning · Computer Science 2024-07-08 Hsin-Yu Chang , Pei-Yu Chen , Tun-Hsiang Chou , Chang-Sheng Kao , Hsuan-Yun Yu , Yen-Ting Lin , Yun-Nung Chen

Synthetic datasets are important for evaluating and testing machine learning models. When evaluating real-life recommender systems, high-dimensional categorical (and sparse) datasets are often considered. Unfortunately, there are not many…

Information Retrieval · Computer Science 2024-12-11 Miha Malenšek , Blaž Škrlj , Blaž Mramor , Jure Demšar

Synthetic tabular data enables sharing and analysis of sensitive records, but its practical deployment requires balancing distributional fidelity, downstream utility, and privacy protection. We study a simple, model agnostic post processing…

Machine Learning · Computer Science 2026-02-09 David Yavo , Richard Khoury , Christophe Pere , Sadoune Ait Kaci Azzou

Synthetic Data is not new, but recent advances in Generative AI have raised interest in expanding the research toolbox, creating new opportunities and risks. This article provides a taxonomy of the full breadth of the Synthetic Data domain.…

Human-Computer Interaction · Computer Science 2024-08-29 Richard Timpone , Yongwei Yang

While data sharing is crucial for knowledge development, privacy concerns and strict regulation (e.g., European General Data Protection Regulation (GDPR)) unfortunately limits its full effectiveness. Synthetic tabular data emerges as an…

Machine Learning · Computer Science 2021-08-24 Aditya Kunar

In the rapidly evolving era of Artificial Intelligence (AI), synthetic data are widely used to accelerate innovation while preserving privacy and enabling broader data accessibility. However, the evaluation of synthetic data remains…

Recent advances in generating synthetic data that allow to add principled ways of protecting privacy -- such as Differential Privacy -- are a crucial step in sharing statistical information in a privacy preserving way. But while the focus…

Machine Learning · Statistics 2021-10-04 Christian Arnold , Marcel Neunhoeffer

Class imbalance can often degrade predictive performance of supervised learning algorithms. Balanced classes can be obtained by oversampling exact copies, with noise, or interpolation between nearest neighbours (as in traditional SMOTE…

Machine Learning · Computer Science 2022-01-17 Emily Muller , Xu Zheng , Jer Hayes

Generative models capable of capturing nuanced clinical features in medical images hold great promise for facilitating clinical data sharing, enhancing rare disease datasets, and efficiently synthesizing annotated medical images at scale.…

Image and Video Processing · Electrical Eng. & Systems 2023-06-23 Shenghuan Sun , Gregory M. Goldgof , Atul Butte , Ahmed M. Alaa

We conduct a scoping review of existing approaches for synthetic EHR data generation, and benchmark major methods with proposed open-source software to offer recommendations for practitioners. We search three academic databases for our…

Machine Learning · Computer Science 2025-06-05 Xingran Chen , Zhenke Wu , Xu Shi , Hyunghoon Cho , Bhramar Mukherjee

Real-world data often exhibits bias, imbalance, and privacy risks. Synthetic datasets have emerged to address these issues. This paradigm relies on generative AI models to generate unbiased, privacy-preserving data while maintaining…

A key challenge for the development and deployment of artificial intelligence (AI) solutions in radiology is solving the associated data limitations. Obtaining sufficient and representative patient datasets with appropriate annotations may…

Image and Video Processing · Electrical Eng. & Systems 2024-07-03 Elena Sizikova , Andreu Badal , Jana G. Delfino , Miguel Lago , Brandon Nelson , Niloufar Saharkhiz , Berkman Sahiner , Ghada Zamzmi , Aldo Badano

Causal inference is essential for developing and evaluating medical interventions, yet real-world medical datasets are often difficult to access due to regulatory barriers. This makes synthetic data a potentially valuable asset that enables…

Machine Learning · Computer Science 2025-10-22 Harry Amad , Zhaozhi Qian , Dennis Frauen , Julianna Piskorz , Stefan Feuerriegel , Mihaela van der Schaar