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Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) is a valuable tool to localize, characterize, and evaluate anomalous prostate tissue. Ultrafast gradient-echo acquisitions of MRI volumes are generated at regular time intervals…

Medical Physics · Physics 2017-10-11 Wuilian Torres , Leonardo Cordero , Miguel Martín-Landrove , Antonio Rueda-Toicen

Deep learning methods, and in particular convolutional neural networks (CNNs), have led to an enormous breakthrough in a wide range of computer vision tasks, primarily by using large-scale annotated datasets. However, obtaining such…

Computer Vision and Pattern Recognition · Computer Science 2019-01-23 Maayan Frid-Adar , Idit Diamant , Eyal Klang , Michal Amitai , Jacob Goldberger , Hayit Greenspan

Publicly available diabetic retinopathy (DR) datasets are imbalanced, containing limited numbers of images with DR. This imbalance contributes to overfitting when training machine learning classifiers. The impact of this imbalance is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-31 Cristina-Madalina Dragan , Muhammad Muneeb Saad , Mubashir Husain Rehmani , Ruairi O'Reilly

Introduction: Quantification of dynamic contrast-enhanced (DCE)-MRI has the potential to provide valuable clinical information, but robust pharmacokinetic modeling remains a challenge for clinical adoption. Methods: A 7-layer neural network…

Medical Physics · Physics 2024-05-22 Ouri Cohen , Soudabeh Kargar , Sungmin Woo , Alberto Vargas , Ricardo Otazo

Deep learning-based computer-aided diagnosis (CAD) of medical images requires large datasets. However, the lack of large publicly available labeled datasets limits the development of deep learning-based CAD systems. Generative Adversarial…

Image and Video Processing · Electrical Eng. & Systems 2025-03-04 Muhammad Rafiq , Hazrat Ali , Ghulam Mujtaba , Zubair Shah , Shoaib Azmat

Hepatocellular carcinoma (HCC) is a common type of liver cancer whose early-stage diagnosis is a common challenge, mainly due to the manual assessment of hematoxylin and eosin-stained whole slide images, which is a time-consuming process…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Ajinkya Deshpande , Deep Gupta , Ankit Bhurane , Nisha Meshram , Sneha Singh , Petia Radeva

Contrast agents in dynamic contrast enhanced magnetic resonance imaging allow to localize tumors and observe their contrast kinetics, which is essential for cancer characterization and respective treatment decision-making. However, contrast…

Magnetic resonance imaging (MRI) is a leading modality for the diagnosis of liver cancer, significantly improving the classification of the lesion and patient outcomes. However, traditional MRI faces challenges including risks from contrast…

Image and Video Processing · Electrical Eng. & Systems 2025-08-14 Xiaojiao Xiao , Jianfeng Zhao , Qinmin Vivian Hu , Guanghui Wang

Deep learning and generative models are advancing rapidly, with synthetic data increasingly being integrated into training pipelines for downstream analysis tasks. However, in medical imaging, their adoption remains constrained by the…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Kyeonghun Kim , Jaehyeok Bae , Youngung Han , Joo Young Bae , Seoyoung Ju , Junsu Lim , Gyeongmin Kim , Nam-Joon Kim , Woo Kyoung Jeong , Ken Ying-Kai Liao , Won Jae Lee , Pa Hong , Hyuk-Jae Lee

Deep transfer learning using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has shown strong predictive power in characterization of breast lesions. However, pretrained convolutional neural networks (CNNs) require 2D inputs,…

Medical Physics · Physics 2019-11-11 Qiyuan Hu , Heather M. Whitney , Maryellen L. Giger

Primary tumors have a high likelihood of developing metastases in the liver and early detection of these metastases is crucial for patient outcome. We propose a method based on convolutional neural networks (CNN) to detect liver metastases.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-16 Mariëlle J. A. Jansen , Hugo J. Kuijf , Maarten Niekel , Wouter B. Veldhuis , Frank J. Wessels , Max A. Viergever , Josien P. W. Pluim

Dynamical contrast enhanced (DCE) imaging allows non invasive access to tissue micro-vascularization. It appears as a promising tool to build imaging biomark-ers for diagnostic, prognosis or anti-angiogenesis treatment monitoring of cancer.…

Image and Video Processing · Electrical Eng. & Systems 2018-10-09 Fuchen Liu , Charles-André Cuénod , Isabelle Thomassin-Naggara , Stéphane Chemouny , Yves Rozenholc

Deep learning is quickly becoming the leading methodology for medical image analysis. Given a large medical archive, where each image is associated with a diagnosis, efficient pathology detectors or classifiers can be trained with virtually…

Computer Vision and Pattern Recognition · Computer Science 2017-06-28 Gwenolé Quellec , Katia Charrière , Yassine Boudi , Béatrice Cochener , Mathieu Lamard

Image registration of liver dynamic contrast-enhanced computed tomography (DCE-CT) is crucial for diagnosis and image-guided surgical planning of liver cancer. However, intensity variations due to the flow of contrast agents combined with…

Image and Video Processing · Electrical Eng. & Systems 2023-03-09 Peng Xue , Jingyang Zhang , Lei Ma , Mianxin Liu , Yuning Gu , Jiawei Huang , Feihong Liua , Yongsheng Pan , Xiaohuan Cao , Dinggang Shen

Image segmentation and registration are said to be challenging when applied to dynamic contrast enhanced MRI sequences (DCE-MRI). The contrast agent causes rapid changes in intensity in the region of interest and elsewhere, which can lead…

Image and Video Processing · Electrical Eng. & Systems 2023-06-23 Adam G. Tattersall , Keith A. Goatman , Lucy E. Kershaw , Scott I. K. Semple , Sonia Dahdouh

Magnetic resonance imaging (MRI) provides varying tissue contrast images of internal organs based on a strong magnetic field. Despite the non-invasive advantage of MRI in frequent imaging, the low contrast MR images in the target area make…

Image and Video Processing · Electrical Eng. & Systems 2020-06-11 Mohammad Hamghalam , Baiying Lei , Tianfu Wang

Magnetic Resonance Images (MRIs) are extremely used in the medical field to detect and better understand diseases. In order to fasten automatic processing of scans and enhance medical research, this project focuses on automatically…

Image and Video Processing · Electrical Eng. & Systems 2020-01-16 Antoine Delplace

Contrast-enhanced magnetic resonance imaging (CE-MRI) plays a crucial role in brain tumor assessment; however, its acquisition requires gadolinium-based contrast agents (GBCAs), which increase costs and raise safety concerns. Consequently,…

Image and Video Processing · Electrical Eng. & Systems 2026-03-23 Atharva Rege , Adinath Madhavrao Dukre , Numan Balci , Dwarikanath Mahapatra , Imran Razzak

Deep learning has potential to automate screening, monitoring and grading of disease in medical images. Pretraining with contrastive learning enables models to extract robust and generalisable features from natural image datasets,…

Early detection of breast cancer has a major contribution to curability, and using mammographic images, this can be achieved non-invasively. Supervised deep learning, the dominant CADe tool currently, has played a great role in object…

Image and Video Processing · Electrical Eng. & Systems 2019-09-06 Basel Alyafi , Oliver Diaz , Robert Marti