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In the field of biomedical image analysis, the quest for architectures capable of effectively capturing long-range dependencies is paramount, especially when dealing with 3D image segmentation, classification, and landmark detection.…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Haifan Gong , Luoyao Kang , Yitao Wang , Xiang Wan , Haofeng Li

The single-cell RNA sequencing (scRNA-seq) technology enables researchers to study complex biological systems and diseases with high resolution. The central challenge is synthesizing enough scRNA-seq samples; insufficient samples can impede…

Genomics · Quantitative Biology 2023-12-25 Yixuan Wang , Shuangyin Li , Shimin DI , Lei Chen

We present a generative framework for inverse design of five-layer transmissive Huygens' metasurfaces (HMSs), addressing a longstanding challenge in achieving full-phase, high-efficiency unit cell designs with minimal full-wave simulations.…

Applied Physics · Physics 2026-03-05 Natanel Nissan , Sherman W. Marcus , Dan Raviv , Raja Giryes , Ariel Epstein

The remarkable success of foundation models has sparked growing interest in their application to single-cell biology. Models like Geneformer and scGPT promise to serve as versatile tools in this specialized field. However, representing a…

Quantitative Methods · Quantitative Biology 2024-11-12 Jiabei Cheng , Jiachen Li , Kaiyuan Yang , Hongbin Shen , Ye Yuan

The ability to measure the transcriptomes of single cells has only been feasible for a few years, and is becoming an extremely popular assay. While many types of analysis and questions can be answered using single cell RNA-sequencing, a…

Genomics · Quantitative Biology 2017-08-09 Valentine Svensson , Roser Vento-Tormo , Sarah A Teichmann

Cross-modal alignment is crucial for multimodal representation fusion due to the inherent heterogeneity between modalities. While Transformer-based methods have shown promising results in modeling inter-modal relationships, their quadratic…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Yan Li , Yifei Xing , Xiangyuan Lan , Xin Li , Haifeng Chen , Dongmei Jiang

Background: Single-cell RNA sequencing (scRNA-seq) is a powerful profiling technique at the single-cell resolution. Appropriate analysis of scRNA-seq data can characterize molecular heterogeneity and shed light into the underlying cellular…

Applications · Statistics 2019-08-05 Siamak Zamani Dadaneh , Paul de Figueiredo , Sing-Hoi Sze , Mingyuan Zhou , Xiaoning Qian

Recent advances in sequence modeling have introduced selective SSMs as promising alternatives to Transformer architectures, offering theoretical computational efficiency and sequence processing advantages. A comprehensive understanding of…

Machine Learning · Computer Science 2025-12-01 Abdullah Al Asif , Mobina Kashaniyan , Sixing Yu , Juan Pablo Muñoz , Ali Jannesari

As one of the most representative DL techniques, Transformer architecture has empowered numerous advanced models, especially the large language models (LLMs) that comprise billions of parameters, becoming a cornerstone in deep learning.…

Machine Learning · Computer Science 2026-04-07 Haohao Qu , Liangbo Ning , Rui An , Wenqi Fan , Tyler Derr , Hui Liu , Xin Xu , Qing Li

In various domains, Sequential Recommender Systems (SRS) have become essential due to their superior capability to discern intricate user preferences. Typically, SRS utilize transformer-based architectures to forecast the subsequent item…

Artificial Intelligence · Computer Science 2024-12-25 Ziwei Liu , Qidong Liu , Yejing Wang , Wanyu Wang , Pengyue Jia , Maolin Wang , Zitao Liu , Yi Chang , Xiangyu Zhao

In the domain of 3D biomedical image segmentation, Mamba exhibits the superior performance for it addresses the limitations in modeling long-range dependencies inherent to CNNs and mitigates the abundant computational overhead associated…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Weitong Wu , Zhaohu Xing , Jing Gong , Qin Peng , Lei Zhu

CrackMamba, a Mamba-based model, is designed for efficient and accurate crack segmentation for monitoring the structural health of infrastructure. Traditional Convolutional Neural Network (CNN) models struggle with limited receptive fields,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Xin Zuo , Yu Sheng , Jifeng Shen , Yongwei Shan

Multimodal single-cell technologies enable the simultaneous collection of diverse data types from individual cells, enhancing our understanding of cellular states. However, the integration of these datatypes and modeling the…

Machine Learning · Computer Science 2023-11-22 Bhavya Mehta , Nirmit Deliwala , Madhav Chandane

Self-supervised Learning (SSL) has become a powerful paradigm for representation learning without manual annotations. However, most existing frameworks focus on global alignment and struggle to capture the hierarchical, multi-scale lesion…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Abdullah Al Mamun , Miaohua Zhang , David Ahmedt-Aristizabal , Zeeshan Hayder , Mohammad Awrangjeb

Semantic segmentation of remote sensing imagery is a fundamental task in computer vision, supporting a wide range of applications such as land use classification, urban planning, and environmental monitoring. However, this task is often…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Qinfeng Zhu , Han Li , Liang He , Lei Fan

We introduce a comprehensive framework for modeling single cell transcriptomic responses to perturbations, aimed at standardizing benchmarking in this rapidly evolving field. Our approach includes a modular and user-friendly model…

Global effective receptive field plays a crucial role for image style transfer (ST) to obtain high-quality stylized results. However, existing ST backbones (e.g., CNNs and Transformers) suffer huge computational complexity to achieve global…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Hongda Liu , Longguang Wang , Ye Zhang , Ziru Yu , Yulan Guo

In recent speech enhancement (SE) research, transformer and its variants have emerged as the predominant methodologies. However, the quadratic complexity of the self-attention mechanism imposes certain limitations on practical deployment.…

Sound · Computer Science 2025-01-03 Junyu Wang , Zizhen Lin , Tianrui Wang , Meng Ge , Longbiao Wang , Jianwu Dang

Deep learning-based single-channel speaker separation has improved significantly in recent years largely due to the introduction of the transformer-based attention mechanism. However, these improvements come at the expense of intense…

Convolutional Neural Networks (CNNs) and Transformers have been the most popular architectures for biomedical image segmentation, but both of them have limited ability to handle long-range dependencies because of inherent locality or…

Image and Video Processing · Electrical Eng. & Systems 2024-01-10 Jun Ma , Feifei Li , Bo Wang
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