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The physical interpretation of the functioning of the adaptive immune system, which has been thoroughly characterized on genetic and molecular levels, provides a unique opportunity to define an adaptive self-organizing biological system in…

Molecular Networks · Quantitative Biology 2023-05-19 Jozsef Prechl

We demonstrate that active rotations in chemically signalling particles, such as autochemotactic {\it E. coli} close to walls, create a route for pattern formation based on a nonlinear yet deterministic instability mechanism. For slow…

Soft Condensed Matter · Physics 2016-08-19 Benno Liebchen , Michael E. Cates , Davide Marenduzzo

This paper studies a stylized model of local interaction where agents choose from an ever increasing set of vertically ranked actions, e.g. technologies. The driving forces of the model are infrequent upward shifts (``updates''), followed…

Statistical Mechanics · Physics 2007-05-23 A. Arenas , A. Diaz-Guilera , C. J. Perez , F. Vega-Redondo

The proper functioning of the nervous system depends critically on the intricate network of synaptic connections that are generated during the system development. During the network formation, the growth cones migrate through the embryonic…

Disordered Systems and Neural Networks · Physics 2007-05-23 Ronen Segev , Eshel Ben-Jacob

What kind of internal organization would allow an artificial agent not only to adapt its behavior, but to sustain a history-sensitive perspective on its world? I present a minimal architecture in which a slow perspective latent $g$ feeds…

Artificial Intelligence · Computer Science 2026-04-07 Hongju Pae

Inputs to signaling pathways can have complex statistics that depend on the environment and on the behavioral response to previous stimuli. Such behavioral feedback is particularly important in navigation. Successful navigation relies on…

Molecular Networks · Quantitative Biology 2014-12-02 Yann S. Dufour , Xiongfei Fu , Luis Hernandez-Nunez , Thierry Emonet

Motile microorganisms, like bacteria and algae, unify abilities like self-propulsion, autonomous navigation, and decision-making on the micron scale. While recent breakthroughs have led to the creation of synthetic microswimmers and…

Soft Condensed Matter · Physics 2026-02-06 Aritra K. Mukhopadhyay , Ran Niu , Linhui Fu , Kai Feng , Christopher Fujta , Qiang Zhao , Jinping Qu , Benno Liebchen

We study numerically the phases and dynamics of a dense collection of self-propelled particles with soft repulsive interactions in two dimensions. The model is motivated by recent in vitro experiments on confluent monolayers of migratory…

Soft Condensed Matter · Physics 2015-05-28 Silke Henkes , Yaouen Fily , M. Cristina Marchetti

A large variety of real systems are composed by entities in relationships which can be represented by networks. In many of these systems, elements are embedded in the space and location information impacts properties and evolution. Local…

Physics and Society · Physics 2021-11-09 Michele Tirico , Stefan Balev , Antoine Dutot , Damien Olivier

Cells self-organize into functional, ordered structures during tissue morphogenesis, a process that is evocative of colloidal self-assembly into engineered soft materials. Understanding how inter-cellular mechanical interactions may drive…

Self-organization in complex systems is a process in which randomness is reduced and emergent structures appear that allow the system to function in a more competitive way with other states of the system or with other systems. It occurs…

Adaptation and Self-Organizing Systems · Physics 2025-06-02 Matthew J Brouillet , Georgi Yordanov Georgiev

With the help of a mathematical model, the metabolic process of the Krebs cycle is studied. The autocatalytic processes resulting in both the formation of the self-organization in the Krebs cycle and the appearance of a cyclicity of its…

Molecular Networks · Quantitative Biology 2017-10-26 V. I. Grytsay , I. V. Musatenko

Most of the grand challenges of humanity today involve complex agent-based systems, such as epidemiology, economics or ecology. However, remains as a pending task the challenge of identifying the general principles underlying their…

General Finance · Quantitative Finance 2020-10-19 Martin Jaraiz

We study the stationary state of a Poisson problem for a system of N perfectly conducting metal balls driven by electric forces to move within a medium of very low electrical conductivity onto which charges are sprayed from outside. When…

Statistical Mechanics · Physics 2009-10-31 Marco Marani , Jayanth R. Banavar , Guido Caldarelli , Amos Maritan , Andrea Rinaldo

Spontaneous pattern formation in living systems is driven by reaction-diffusion chemistry and active mechanics. The feedback between chemical and mechanical forces is often essential to robust pattern formation, yet it remains poorly…

Soft Condensed Matter · Physics 2022-01-20 Clara del Junco , André Estevez-Torres , Ananyo Maitra

Since a spatial distribution of communication requests is inhomogeneous and related to a population, in constructing a network, it is crucial for delivering packets on short paths through the links between proximity nodes and for…

Physics and Society · Physics 2012-07-31 Yukio Hayashi

We experimentally investigate how aerotactic bacteria, confined within a thin liquid film between two solid substrates, respond to a controlled oxygen gradient. We find that the total bacterial number density dictates which mechanism…

Soft Condensed Matter · Physics 2026-04-07 Minjun Kim , Joonwoo Jeong

Motile bacteria can migrate along chemical gradients in a process known as chemotaxis. When exposed to uniform environmental stress, Escherichia coli cells coordinate their chemotactic responses to form millimeter-sized condensates…

Biological Physics · Physics 2025-05-02 Nir Livne , Ady Vaknin , Oded Agam

Bacterial colonies growing on surfaces are shaped by mechanical stresses transmitted through the community, governed by the balance between cell growth and steric and cell-substrate interactions. Using overdamped dynamics simulations of…

Soft Condensed Matter · Physics 2026-01-14 Samaneh Rahbar , Ludger Santen , Reza Shaebani

As a model of temporally evolving networks, we consider a globally coupled logistic map with variable connection weights. The model exhibits self-organization of network structure, reflected by the collective behavior of units. Structural…

Disordered Systems and Neural Networks · Physics 2009-11-07 Junji Ito , Kunihiko Kaneko