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Mathematical modeling of disease spreading plays a crucial role in understanding, controlling and preventing epidemic outbreaks. In a microscopic description of the propagation of a disease over the complex network of human contacts, the…

Physics and Society · Physics 2021-10-08 Federico Malizia , Luca Gallo , Mattia Frasca , Vito Latora , Giovanni Russo

We study the Susceptible-Infected-Recovered (SIR) and the Susceptible-Exposed-Infected-Recovered (SEIR) models of epidemics, with possibly time-varying rates, on a class of networks that are locally tree-like, which includes sparse…

Probability · Mathematics 2023-09-22 Juniper Cocomello , Kavita Ramanan

Modeling and forecasting the spread of infectious diseases is essential for effective public health decision-making. Traditional epidemiological models rely on expert-defined frameworks to describe complex dynamics, while neural networks,…

Machine Learning · Computer Science 2024-12-31 Jianda Du , Senwei Liang , Chunmei Wang

Mathematical models of infectious disease transmission typically neglect within-host dynamics. Yet within-host dynamics - including pathogen replication, host immune responses, and interactions with microbiota - are crucial not only for…

Populations and Evolution · Quantitative Biology 2023-12-20 Cameron A. Smith , Ben Ashby

In this work, we introduce a quantum-inspired epidemic model to study the dynamics of an infectious disease in a population divided into compartments. By treating the healthy population as a large reservoir, we construct a framework based…

Populations and Evolution · Quantitative Biology 2025-03-19 Fabio Bagarello , Francesco Gargano , Polina Khrennikova

The effect of spatial correlations on the spread of infectious diseases was investigated using a stochastic SIR (Susceptible-Infective-Recovered) model on complex networks. It was found that in addition to the reduction of the effective…

Populations and Evolution · Quantitative Biology 2007-05-23 J. Verdasca , M. M. Telo da Gama , A. Nunes , N. R. Bernardino , J. M. Pacheco , M. C. Gomes

The modelling and analysis of biological systems has deep roots in Mathematics, specifically in the field of ordinary differential equations (ODEs). Alternative approaches based on formal calculi, often derived from process algebras or term…

Programming Languages · Computer Science 2010-11-03 Mario Coppo , Ferruccio Damiani , Maurizio Drocco , Elena Grassi , Eva Sciacca , Salvatore Spinella , Angelo Troina

Models of disease spreading are critical for predicting infection growth in a population and evaluating public health policies. However, standard models typically represent the dynamics of disease transmission between individuals using…

Physics and Society · Physics 2022-06-07 Christopher A. Browne , Daniel B. Amchin , Joanna Schneider , Sujit S. Datta

The SIR-compartment model is among the simplest models that describe the spread of a disease through a population. The model makes the unrealistic assumption that the population through which the disease is spreading is well-mixed. Although…

Populations and Evolution · Quantitative Biology 2022-11-16 Ryan Wilkinson , Marcus Roper

The fundamental models of epidemiology describe the progression of an infectious disease through a population using compartmentalized differential equations, but do not incorporate population-level heterogeneity in infection susceptibility.…

Populations and Evolution · Quantitative Biology 2023-08-04 Christopher Rose , Andrew J. Medford , C. Franklin Goldsmith , Tejs Vegge , Joshua S. Weitz , Andrew A. Peterson

The spreading of epidemics is very much determined by the structure of the contact network, which may be impacted by the mobility dynamics of the individuals themselves. In confined scenarios where a small, closed population spends most of…

Physics and Society · Physics 2018-05-09 Clara Granell , Peter J. Mucha

Epidemic disease spreading is conventionally often modelled and analyzed by means of rate and diffusion equations, following the paradigms of well-controlled chemical reactions and diffusive dynamics in a test tube. Yet, serious worries…

Physics and Society · Physics 2023-01-03 Klaus Kroy

Epidemiological models describe the spread of an infectious disease within a population. They capture microscopic details on how the disease is passed on among individuals in various different ways, while making predictions about the state…

Populations and Evolution · Quantitative Biology 2024-02-27 Stefan Hohenegger , Francesco Sannino

Mathematical models describing the spatial spreading and invasion of populations of biological cells are often developed in a continuum modelling framework using reaction-diffusion equations. While continuum models based on linear diffusion…

Cellular Automata and Lattice Gases · Physics 2024-01-23 Matthew J Simpson , Keeley M Murphy , Scott W McCue , Pascal R Buenzli

Ordinary differential equations (ODE) are a popular tool to model the spread of infectious diseases, yet they implicitly assume an exponential distribution to describe the flow from one infection state to another. However, scientific…

Numerical Analysis · Mathematics 2025-10-13 Anna Wendler , Lena Plötzke , Hannah Tritzschak , Martin J. Kühn

The aim of this paper is to present an, admittedly somewhat subjective, bird's eye view of the mathematical theory concerning the spread of an infectious disease in a susceptible host population with static structure, culminating in a…

Populations and Evolution · Quantitative Biology 2025-08-06 Odo Diekmann , Hisashi Inaba , Horst R. Thieme

We consider the spread of infectious disease through contact networks of Configuration Model type. We assume that the disease spreads through contacts and infected individuals recover into an immune state. We discuss a number of existing…

Populations and Evolution · Quantitative Biology 2014-03-11 Joel C Miller , Istvan Z Kiss

Compartmental equations are primary tools in disease spreading studies. Their predictions are accurate for large populations but disagree with empirical and simulated data for finite populations, where uncertainties become a relevant…

Populations and Evolution · Quantitative Biology 2018-07-18 GM Nakamura , ND Gomes , GC Cardoso , AS Martinez

We demonstrate how direct simulation of stochastic, individual-based models can be combined with continuum numerical analysis techniques to study the dynamics of evolving diseases. % Sidestepping the necessity of obtaining explicit…

Adaptation and Self-Organizing Systems · Physics 2009-11-10 Jaime Cisternas , C. William Gear , Simon Levin , Ioannis G. Kevrekidis

Epidemiological models can not only be used to forecast the course of a pandemic like COVID-19, but also to propose and design non-pharmaceutical interventions such as school and work closing. In general, the design of optimal policies…

Optimization and Control · Mathematics 2023-04-06 Jan-Hendrik Niemann , Samuel Uram , Sarah Wolf , Nataša Djurdjevac Conrad , Martin Weiser