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Visual microscopic study of diseased tissue by pathologists has been the cornerstone for cancer diagnosis and prognostication for more than a century. Recently, deep learning methods have made significant advances in the analysis and…

Image and Video Processing · Electrical Eng. & Systems 2022-09-30 Puria Azadi Moghadam , Sanne Van Dalen , Karina C. Martin , Jochen Lennerz , Stephen Yip , Hossein Farahani , Ali Bashashati

Magnetic resonance (MR) imaging, including cardiac MR, is prone to domain shift due to variations in imaging devices and acquisition protocols. This challenge limits the deployment of trained AI models in real-world scenarios, where…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Xin Ci Wong , Duygu Sarikaya , Kieran Zucker , Marc De Kamps , Nishant Ravikumar

The rapid advancement of generative models, such as Stable Diffusion, raises a key question: how can synthetic data from these models enhance predictive modeling? While they can generate vast amounts of datasets, only a subset meaningfully…

Machine Learning · Statistics 2025-05-09 Jialong Jiang , Wenkang Hu , Jian Huang , Yuling Jiao , Xu Liu

Multi-modal foundation models are typically trained on millions of pairs of natural images and text captions, frequently obtained through web-crawling approaches. Although such models depict excellent generative capabilities, they do not…

Computer Vision and Pattern Recognition · Computer Science 2023-01-03 Pierre Chambon , Christian Bluethgen , Curtis P. Langlotz , Akshay Chaudhari

To achieve high-quality results, diffusion models must be trained on large datasets. This can be notably prohibitive for models in specialized domains, such as computational pathology. Conditioning on labeled data is known to help in…

Computer Vision and Pattern Recognition · Computer Science 2023-12-04 Srikar Yellapragada , Alexandros Graikos , Prateek Prasanna , Tahsin Kurc , Joel Saltz , Dimitris Samaras

The artificial intelligence (AI) world is running out of real data for training increasingly large generative models, resulting in accelerating pressure to train on synthetic data. Unfortunately, training new generative models with…

Machine Learning · Computer Science 2024-08-30 Sina Alemohammad , Ahmed Imtiaz Humayun , Shruti Agarwal , John Collomosse , Richard Baraniuk

Large-scale, big-variant, high-quality data are crucial for developing robust and successful deep-learning models for medical applications since they potentially enable better generalization performance and avoid overfitting. However, the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Zheyuan Zhang , Lanhong Yao , Bin Wang , Debesh Jha , Gorkem Durak , Elif Keles , Alpay Medetalibeyoglu , Ulas Bagci

The accuracy of face recognition systems has improved significantly in the past few years, thanks to the large amount of data collected and advancements in neural network architectures. However, these large-scale datasets are often…

Computer Vision and Pattern Recognition · Computer Science 2025-01-15 Anjith George , Sebastien Marcel

Recent progress in generative AI, primarily through diffusion models, presents significant challenges for real-world deepfake detection. The increased realism in image details, diverse content, and widespread accessibility to the general…

Computer Vision and Pattern Recognition · Computer Science 2024-04-03 Chaitali Bhattacharyya , Hanxiao Wang , Feng Zhang , Sungho Kim , Xiatian Zhu

Recent advances in deep learning have significantly increased the performance of face recognition systems. The performance and reliability of these models depend heavily on the amount and quality of the training data. However, the…

Computer Vision and Pattern Recognition · Computer Science 2018-02-19 Adam Kortylewski , Andreas Schneider , Thomas Gerig , Bernhard Egger , Andreas Morel-Forster , Thomas Vetter

Training machine learning models on massive datasets is expensive and time-consuming. Dataset distillation addresses this by creating a small synthetic dataset that achieves the same performance as the full dataset. Recent methods use…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Jeffrey A. Chan-Santiago , Mubarak Shah

This study explores the utilization of Dermatoscopic synthetic data generated through stable diffusion models as a strategy for enhancing the robustness of machine learning model training. Synthetic data generation plays a pivotal role in…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Muhammad Ali Farooq , Wang Yao , Michael Schukat , Mark A Little , Peter Corcoran

Achieving robust performance and fairness across diverse patient populations remains a challenge in developing clinically deployable deep learning models for diagnostic imaging. Synthetic data generation has emerged as a promising strategy…

In this paper, we introduce the first diffusion model designed to generate complete synthetic human genotypes, which, by standard protocols, one can straightforwardly expand into full-length, DNA-level genomes. The synthetic genotypes mimic…

Computational Engineering, Finance, and Science · Computer Science 2025-01-31 Philip Kenneweg , Raghuram Dandinasivara , Xiao Luo , Barbara Hammer , Alexander Schönhuth

Nuclei segmentation and classification is a significant process in pathology image analysis. Deep learning-based approaches have greatly contributed to the higher accuracy of this task. However, those approaches suffer from the imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Hyun-Jic Oh , Won-Ki Jeong

Diffusion models have proven to be highly effective in generating high-quality images. However, adapting large pre-trained diffusion models to new domains remains an open challenge, which is critical for real-world applications. This paper…

Computer Vision and Pattern Recognition · Computer Science 2023-07-28 Enze Xie , Lewei Yao , Han Shi , Zhili Liu , Daquan Zhou , Zhaoqiang Liu , Jiawei Li , Zhenguo Li

Synthetic data has recently reached a level of visual fidelity that makes it nearly indistinguishable from real data, offering great promise for privacy-preserving data sharing in medical imaging. However, fully synthetic datasets still…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Mischa Dombrowski , Bernhard Kainz

Histopathology images; microscopy images of stained tissue biopsies contain fundamental prognostic information that forms the foundation of pathological analysis and diagnostic medicine. However, diagnostics from histopathology images…

Computer Vision and Pattern Recognition · Computer Science 2019-10-30 Aïcha BenTaieb , Ghassan Hamarneh

Recent work has shown improved lesion detectability and flexibility to reconstruction hyperparameters (e.g. scanner geometry or dose level) when PET images are reconstructed by leveraging pre-trained diffusion models. Such methods train a…

Medical Physics · Physics 2025-08-28 George Webber , Alexander Hammers , Andrew P. King , Andrew J. Reader

The remarkable ease of use of diffusion models for image generation has led to a proliferation of synthetic content online. While these models are often employed for legitimate purposes, they are also used to generate fake images that…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Giulia Bertazzini , Daniele Baracchi , Dasara Shullani , Isao Echizen , Alessandro Piva