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Classifier-free guided diffusion models have recently been shown to be highly effective at high-resolution image generation, and they have been widely used in large-scale diffusion frameworks including DALLE-2, Stable Diffusion and Imagen.…

Computer Vision and Pattern Recognition · Computer Science 2023-04-14 Chenlin Meng , Robin Rombach , Ruiqi Gao , Diederik P. Kingma , Stefano Ermon , Jonathan Ho , Tim Salimans

Incorporating diffusion-generated synthetic data into adversarial training (AT) has been shown to substantially improve the training of robust image classifiers. In this work, we extend the role of diffusion models beyond merely generating…

Machine Learning · Computer Science 2026-02-24 Pin-Han Huang , Shang-Tse Chen , Hsuan-Tien Lin

Diffusion models have achieved significant success in both natural image and medical image domains, encompassing a wide range of applications. Previous investigations in medical images have often been constrained to specific anatomical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-08 Yongrui Yu , Yannian Gu , Shaoting Zhang , Xiaofan Zhang

Conditional generative models typically demand large annotated training sets to achieve high-quality synthesis. As a result, there has been significant interest in designing models that perform plug-and-play generation, i.e., to use a…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Nithin Gopalakrishnan Nair , Anoop Cherian , Suhas Lohit , Ye Wang , Toshiaki Koike-Akino , Vishal M. Patel , Tim K. Marks

Integrating deep learning with clinical expertise holds great potential for addressing healthcare challenges and empowering medical professionals with improved diagnostic tools. However, the need for annotated medical images is often an…

Computer Vision and Pattern Recognition · Computer Science 2023-11-16 Romain Hardy , Joe Klepich , Ryan Mitchell , Steve Hall , Jericho Villareal , Cornelia Ilin

Data sharing in the medical image analysis field has potential yet remains underappreciated. The aim is often to share datasets efficiently with other sites to train models effectively. One possible solution is to avoid transferring the…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Muyang Li , Can Cui , Quan Liu , Ruining Deng , Tianyuan Yao , Marilyn Lionts , Yuankai Huo

The success of AI models relies on the availability of large, diverse, and high-quality datasets, which can be challenging to obtain due to data scarcity, privacy concerns, and high costs. Synthetic data has emerged as a promising solution…

Computation and Language · Computer Science 2024-08-13 Ruibo Liu , Jerry Wei , Fangyu Liu , Chenglei Si , Yanzhe Zhang , Jinmeng Rao , Steven Zheng , Daiyi Peng , Diyi Yang , Denny Zhou , Andrew M. Dai

We present a novel diffusion-based approach to generate synthetic histopathological Whole Slide Images (WSIs) at an unprecedented gigapixel scale. Synthetic WSIs have many potential applications: They can augment training datasets to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-15 Robert Harb , Thomas Pock , Heimo Müller

Diffusion models have achieved state-of-the-art results on many modalities including images, speech, and video. However, existing models are not tailored to support remote sensing data, which is widely used in important applications…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Samar Khanna , Patrick Liu , Linqi Zhou , Chenlin Meng , Robin Rombach , Marshall Burke , David Lobell , Stefano Ermon

Variable selection for high-dimensional, highly correlated data has long been a challenging problem, often yielding unstable and unreliable models. We propose a resample-aggregate framework that exploits diffusion models' ability to…

Methodology · Statistics 2025-08-20 Minjie Wang , Xiaotong Shen , Wei Pan

Data availability remains a critical bottleneck in many deep learning applications. Large-scale datasets are often expensive to collect, curate and annotate, which can limit the scalability and applicability of supervised learning methods.…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Nithesh Chandher Karthikeyan , Jonas Unger , Gabriel Eilertsen

Modeling and manufacturing of personalized cranial implants are important research areas that may decrease the waiting time for patients suffering from cranial damage. The modeling of personalized implants may be partially automated by the…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Marek Wodzinski , Kamil Kwarciak , Mateusz Daniol , Daria Hemmerling

Low-quality or scarce data has posed significant challenges for training deep neural networks in practice. While classical data augmentation cannot contribute very different new data, diffusion models opens up a new door to build…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Yijun Liang , Shweta Bhardwaj , Tianyi Zhou

Health risk prediction is one of the fundamental tasks under predictive modeling in the medical domain, which aims to forecast the potential health risks that patients may face in the future using their historical Electronic Health Records…

Machine Learning · Computer Science 2023-10-09 Yuan Zhong , Suhan Cui , Jiaqi Wang , Xiaochen Wang , Ziyi Yin , Yaqing Wang , Houping Xiao , Mengdi Huai , Ting Wang , Fenglong Ma

Supervised machine learning has enabled accurate pathology detection in brain MRI, but requires training data from diseased subjects that may not be readily available in some scenarios, for example, in the case of rare diseases.…

Image and Video Processing · Electrical Eng. & Systems 2025-06-13 Ana Lawry Aguila , Peirong Liu , Oula Puonti , Juan Eugenio Iglesias

Content generation modeling has emerged as a promising direction in computational pathology, offering capabilities such as data-efficient learning, synthetic data augmentation, and task-oriented generation across diverse diagnostic tasks.…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Yuan Zhang , Xinfeng Zhang , Xiaoming Qi , Xinyu Wu , Feng Chen , Guanyu Yang , Huazhu Fu

Programmatically generated synthetic data has been used in differential private training for classification to enhance performance without privacy leakage. However, as the synthetic data is generated from a random process, the distribution…

Machine Learning · Computer Science 2024-12-16 Yujin Choi , Jinseong Park , Junyoung Byun , Jaewook Lee

The success of agricultural artificial intelligence depends heavily on large, diverse, and high-quality plant image datasets, yet collecting such data in real field conditions is costly, labor intensive, and seasonally constrained. This…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Da Tan , Michael Beck , Christopher P. Bidinosti , Robert H. Gulden , Christopher J. Henry

Dataset distillation provides an effective approach to reduce memory and computational costs by optimizing a compact dataset that achieves performance comparable to the full original. However, for large-scale datasets and complex deep…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Xinhao Zhong , Shuoyang Sun , Xulin Gu , Zhaoyang Xu , Yaowei Wang , Min Zhang , Bin Chen

The rapid advancement of Artificial Intelligence (AI) in biomedical imaging and radiotherapy is hindered by the limited availability of large imaging data repositories. With recent research and improvements in denoising diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-03-27 Rowan Bradbury , Katherine A. Vallis , Bartlomiej W. Papiez
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