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Information from related source studies can often enhance the findings of a target study. However, the distribution shift between target and source studies can severely impact the efficiency of knowledge transfer. In the high-dimensional…

Methodology · Statistics 2025-11-26 Ruiqi Bai , Yijiao Zhang , Hanbo Yang , Zhongyi Zhu

Multimodal evidence is critical in computational pathology: gigapixel whole slide images capture tumor morphology, while patient-level clinical descriptors preserve complementary context for prognosis. Integrating such heterogeneous signals…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Chengying She , Chengwei Chen , Xinran Zhang , Ben Wang , Lizhuang Liu , Chengwei Shao , Yun Bian

Sepsis is a life-threatening condition caused by the body's response to an infection. In order to treat patients with sepsis, physicians must control varying dosages of various antibiotics, fluids, and vasopressors based on a large number…

Machine Learning · Computer Science 2019-12-17 Amirhossein Kiani , Chris Wang , Angela Xu

We propose a general index model for survival data, which generalizes many commonly used semiparametric survival models and belongs to the framework of dimension reduction. Using a combination of geometric approach in semiparametrics and…

Statistics Theory · Mathematics 2017-10-17 Ge Zhao , Yanyuan Ma , Wenbin Lu

Due to label scarcity and covariate shift happening frequently in real-world studies, transfer learning has become an essential technique to train models generalizable to some target populations using existing labeled source data. Most…

Methodology · Statistics 2022-11-09 Doudou Zhou , Molei Liu , Mengyan Li , Tianxi Cai

Recent years have been marked with the fast-pace diversification and increasing ubiquity of machine learning applications. Yet, a firm theoretical understanding of the surprising efficiency of neural networks to learn from high-dimensional…

Machine Learning · Statistics 2025-01-16 Hugo Cui

Sepsis is a leading cause of death in the Intensive Care Units (ICU). Early detection of sepsis is critical for patient survival. In this paper, we propose a multimodal Transformer model for early sepsis prediction, using the physiological…

Machine Learning · Computer Science 2022-03-29 Yuqing Wang , Yun Zhao , Rachael Callcut , Linda Petzold

The proliferation of early diagnostic technologies, including self-monitoring systems and wearables, coupled with the application of these technologies on large segments of healthy populations may significantly aggravate the problem of…

Machine Learning · Computer Science 2021-07-23 Anna Fedyukova , Douglas Pires , Daniel Capurro

We introduce Minimal Achievable Sufficient Statistic (MASS) Learning, a training method for machine learning models that attempts to produce minimal sufficient statistics with respect to a class of functions (e.g. deep networks) being…

Machine Learning · Computer Science 2019-06-13 Milan Cvitkovic , Günther Koliander

Efficient and scalable non-parametric or semi-parametric regression analysis and density estimation are of crucial importance to the fields of statistics and machine learning. However, available methods are limited in their ability to…

Machine Learning · Computer Science 2026-03-23 Zeyu Ding , Katja Ickstadt , Nadja Klein , Alexander Munteanu , Simon Omlor

There are significant regional inequities in health resources around the world. It has become one of the most focused topics to improve health services for data-scarce hospitals and promote health equity through knowledge sharing among…

Machine Learning · Computer Science 2023-03-07 Ruiqing Ding , Fangjie Rong , Xiao Han , Leye Wang

We develop new algorithms for estimating heterogeneous treatment effects, combining recent developments in transfer learning for neural networks with insights from the causal inference literature. By taking advantage of transfer learning,…

Health care is one of the most exciting frontiers in data mining and machine learning. Successful adoption of electronic health records (EHRs) created an explosion in digital clinical data available for analysis, but progress in machine…

Machine Learning · Statistics 2019-08-13 Hrayr Harutyunyan , Hrant Khachatrian , David C. Kale , Greg Ver Steeg , Aram Galstyan

In this report we review memory-based meta-learning as a tool for building sample-efficient strategies that learn from past experience to adapt to any task within a target class. Our goal is to equip the reader with the conceptual…

Semisupervised methods inevitably invoke some assumption that links the marginal distribution of the features to the regression function of the label. Most commonly, the cluster or manifold assumptions are used which imply that the…

Statistics Theory · Mathematics 2011-12-02 Martin Azizyan , Aarti Singh , Larry Wasserman

Given the increasing complexity of omics datasets, a key challenge is not only improving classification performance but also enhancing the transparency and reliability of model decisions. Effective model performance and feature selection…

Machine Learning · Computer Science 2025-05-07 Diego Perazzolo , Pietro Fanton , Ilaria Barison , Marny Fedrigo , Annalisa Angelini , Chiara Castellani , Enrico Grisan

In practice, it is very demanding and sometimes impossible to collect datasets of tagged data large enough to successfully train a machine learning model, and one possible solution to this problem is transfer learning. This study aims to…

Machine Learning · Computer Science 2022-01-13 Erik Otović , Marko Njirjak , Dario Jozinović , Goran Mauša , Alberto Michelini , Ivan Štajduhar

In the field of lung cancer research, particularly in the analysis of overall survival (OS), artificial intelligence (AI) serves crucial roles with specific aims. Given the prevalent issue of missing data in the medical domain, our primary…

Machine Learning · Computer Science 2026-03-13 Camillo Maria Caruso , Valerio Guarrasi , Sara Ramella , Paolo Soda

The disease trajectory for clinical sepsis, in terms of temporal cytokine and phenotypic dynamics, can be interpreted as a random dynamical system. The ability to make accurate predictions about patient state from clinical measurements has…

Quantitative Methods · Quantitative Biology 2020-07-30 Dale Larie , Gary An , Chase Cockrell

We introduce and study two new inferential challenges associated with the sequential detection of change in a high-dimensional mean vector. First, we seek a confidence interval for the changepoint, and second, we estimate the set of indices…

Methodology · Statistics 2023-03-03 Yudong Chen , Tengyao Wang , Richard J. Samworth
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