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Sepsis-induced acute respiratory failure (ARF) is a serious complication with a poor prognosis. This paper presents a deep representation learningbased phenotyping method to identify distinct groups of clinical trajectories of septic…

Signal Processing · Electrical Eng. & Systems 2024-05-07 Alan Wu , Tilendra Choudhary , Pulakesh Upadhyaya , Ayman Ali , Philip Yang , Rishikesan Kamaleswaran

We consider the problem of predicting how the likelihood of an outcome of interest for a patient changes over time as we observe more of the patient data. To solve this problem, we propose a supervised contrastive learning framework that…

Machine Learning · Computer Science 2024-04-16 Shahriar Noroozizadeh , Jeremy C. Weiss , George H. Chen

Multi-task learning is effective for related applications, but its performance can deteriorate when the target sample size is small. Transfer learning can borrow strength from related studies; yet, many existing methods rely on restrictive…

Machine Learning · Computer Science 2026-04-23 Boxin Zhao , Mladen Kolar , Jinchi Lv

The features in high dimensional biomedical prediction problems are often well described with lower dimensional manifolds. An example is genes that are organised in smaller functional networks. The outcome can then be described with the…

Multi-omics data present significant challenges for statistical inference due to the complex interdependencies among biological layers. In this paper, we introduce a novel Multi-Omics Factor-Adjusted Cox (MOFA-Cox) model for analyzing…

Methodology · Statistics 2025-10-07 Heyuan Zhang , Meiling Hao , Lianqiang Qu , Liuquan Sun

Transfer Learning aims to optimally aggregate samples from a target distribution, with related samples from a so-called source distribution to improve target risk. Multiple procedures have been proposed over the last two decades to address…

Machine Learning · Statistics 2025-04-29 Steve Hanneke , Samory Kpotufe

Absence of large-scale labeled data in the practitioner's target domain can be a bottleneck to applying machine learning algorithms in practice. Transfer learning is a popular strategy for leveraging additional data to improve the…

Machine Learning · Computer Science 2022-06-22 Tianshi Cao , Sasha Doubov , David Acuna , Sanja Fidler

Longitudinal observational patient data can be used to investigate the causal effects of time-varying treatments on time-to-event outcomes. Several methods have been developed for controlling for the time-dependent confounding that…

Methodology · Statistics 2021-10-08 Ruth H. Keogh , Jon Michael Gran , Shaun R. Seaman , Gwyneth Davies , Stijn Vansteelandt

Deep learning based disease detection and segmentation algorithms promise to improve many clinical processes. However, such algorithms require vast amounts of annotated training data, which are typically not available in the medical context…

Image and Video Processing · Electrical Eng. & Systems 2021-11-02 Moritz Platscher , Jonathan Zopes , Christian Federau

Sepsis is a lethal syndrome of organ dysfunction that is triggered by an infection and claims 11 million lives per year globally. Prognostic algorithms based on deep learning have shown promise in detecting the onset of sepsis hours before…

Tissues and Organs · Quantitative Biology 2024-08-19 Marco Giordano , Kanika Dheman , Michele Magno

Across many domains of science, stochastic models are an essential tool to understand the mechanisms underlying empirically observed data. Models can be of different levels of detail and accuracy, with models of high-fidelity (i.e., high…

This paper considers the estimation and prediction of a high-dimensional linear regression in the setting of transfer learning, using samples from the target model as well as auxiliary samples from different but possibly related regression…

Methodology · Statistics 2020-06-19 Sai Li , T. Tony Cai , Hongzhe Li

Recently, transfer learning and self-supervised learning have gained significant attention within the medical field due to their ability to mitigate the challenges posed by limited data availability, improve model generalisation, and reduce…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Zehui Zhao , Laith Alzubaidi , Jinglan Zhang , Ye Duan , Usman Naseem , Yuantong Gu

Over the last year, the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and its variants have highlighted the importance of screening tools with high diagnostic accuracy for new illnesses such as COVID-19. To that regard, deep…

Image and Video Processing · Electrical Eng. & Systems 2022-04-26 Danilo Avola , Andrea Bacciu , Luigi Cinque , Alessio Fagioli , Marco Raoul Marini , Riccardo Taiello

With the rapid development of data collection and aggregation technologies in many scientific disciplines, it is becoming increasingly ubiquitous to conduct large-scale or online regression to analyze real-world data and unveil real-world…

Methodology · Statistics 2021-03-22 Jinfeng Xu , Zhiliang Ying , Na Zhao

Predicting the incidence of complex chronic conditions such as heart failure is challenging. Deep learning models applied to rich electronic health records may improve prediction but remain unexplainable hampering their wider use in medical…

Task transfer learning is a popular technique in image processing applications that uses pre-trained models to reduce the supervision cost of related tasks. An important question is to determine task transferability, i.e. given a common…

Machine Learning · Computer Science 2022-12-21 Yajie Bao , Yang Li , Shao-Lun Huang , Lin Zhang , Lizhong Zheng , Amir Zamir , Leonidas Guibas

We consider statistical inference for a finite-dimensional parameter in a regular semiparametric model under a distributed setting with blockwise missingness, where entire blocks of variables are unavailable at certain sites and sharing…

Methodology · Statistics 2025-08-26 Jingyue Huang , Huiyuan Wang , Yuqing Lei , Yong Chen

Reliability inference based on parametric distributions is an important problem in electrical and mechanical engineering. Most existing methods rely on approximations or bootstrap procedures, which may not perform satisfactorily when data…

Methodology · Statistics 2026-04-15 Bowen Liu , Malwane M. A. Ananda , Sam Weerahandi

In the intensive care unit, the underlying causes of critical illness vary substantially across diagnoses, yet prediction models accounting for diagnostic heterogeneity have not been systematically studied. To address the gap, we evaluate…

Machine Learning · Computer Science 2025-12-09 Mengqi Xu , Subha Maity , Joel Dubin
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