Related papers: Tumor-immune cell interactions by a fully paraboli…
We propose and study a class of parabolic-ODE models involving chemotaxis and haptotaxis of a species following signals indirectly produced by another, non-motile one. The setting is motivated by cancer invasion mediated by interactions…
This paper investigates the repulsive chemotaxis-consumption model \begin{align*} \partial_t u &= \nabla \cdot (D(u) \nabla u) + \nabla \cdot (u \nabla v), \\ 0 &= \Delta v - uv \end{align*} in an $n$-dimensional ball, $n \ge 3$, where the…
We consider a two-species chemotaxis model in $\R^d(d \ge 3)$ featuring nonlinear porous medium-type diffusion and nonlocal attractive power-law interaction. Here, the nonlinear diffusion is chosen to be $1/m_1+1/m_2=(d+2)/d$ in such a way…
In bounded $n$-dimensonal domains with $n\ge 1$, this manuscript examines an initial-boundary value problem for the system \[ \left\{ \begin{array}{l} u_{tt} = \nabla \cdot (\gamma(\Theta) \nabla u_t) + a \nabla \cdot (\gamma(\Theta) \nabla…
In this paper, a reaction-diffusion system modeling injection of a chemotherapeutic drug on the surface of a living tissue during a treatment for cancer patients is studied. The system describes the interaction of the chemotherapeutic drug…
The main purpose of this paper is to analyze the dynamics of the system of time-delay differential equations (DDEs) \begin{equation*} \begin{split} \dot{T}(t)&=T(t) f(t,T(t))-\gamma E(t)T(t),\\ \dot{E}(t)&=\sigma+…
This paper studies a chemotaxis system where cells move in response to a chemical signal within a confined habitat. The model includes external source terms that combine local and nonlocal growth with dampening effects. The main focus is on…
This series of papers is concerned with the global solvability, boundedness, regularity, and uniqueness of weak solutions to the following parabolic-parabolic chemotaxis system with a logistic source and chemical consumption:…
We study a doubly tactic resource consumption model \bess \left\{\begin{array}{lll} u_t=\tr u-\nabla\cd(u\nabla w),\\[1mm] v_t=\tr v-\nabla\cd(v\nabla u)+v(1-v^{\beta-1}),\\[1mm] w_t=\tr w-(u+v)w-w+r \end{array}\right. \eess in a smooth…
Spatial interactions between cancer and immune cells, as well as the recognition of tumour antigens by cells of the immune system, play a key role in the immune response against solid tumours. The existing mathematical models generally…
The combination of cytotoxic therapies and anti-angiogenic agents is emerging as a most promising strategy in the treatment of malignant tumors. However, the timing and sequencing of these treatments seem to play essential roles in…
Solutions $(u, v)$ to the chemotaxis system \begin{align*} \begin{cases} u_t = \nabla \cdot ( (u+1)^{m-1} \nabla u - u (u+1)^{q-1} \nabla v), \\ \tau v_t = \Delta v - v + u \end{cases} \end{align*} in a ball $\Omega \subset \mathbb R^n$, $n…
The classical macroscopic chemotaxis equations have previously been derived from an individual-based description of the tactic response of cells that use a "run-and-tumble" strategy in response to environmental cues. Here we derive…
Immunotherapy is currently regarded as the most promising treatment to fight against cancer. This is particularly true in the treatment of chronic lymphocytic leukemia, an indolent neoplastic disease of B-lymphocytes which eventually causes…
Perhaps the most classical diffusion model for chemotaxis is the Keller-Segel system $\begin{equation} \begin{cases} u_{t} =\Delta u - \nabla \cdot(u \nabla v) \ \ \ \text{in } \mathbb{R}^2\times(0,T),\\[5pt] v =…
This paper studies a fractional attraction-repulsion system with generalized logistic source and nonlinear productions: \begin{equation*} \left\{ \begin{aligned} &u_t = -(-\Delta)^\alpha u - \chi_1 \nabla \cdot (u \nabla v) + \chi_2 \nabla…
This paper deals with the homogeneous Neumann boundary-value problem for the chemotaxis-consumption system \begin{eqnarray*} \begin{array}{llc} u_t=\Delta u-\chi\nabla\cdot (u\nabla v)+\kappa u-\mu u^2,\\ v_t=\Delta v-uv, \end{array}…
We present a model for the interaction dynamics of lymphocytes-tumor cells population. This model reproduces all known states for the tumor. Futherly,we develop it taking into account periodical immunotheraphy treatment with cytokines…
This paper deals with nonnegative solutions of the Neumann initial-boundary value problem for the fully parabolic chemotaxis-growth system $ (u_{\varepsilon})_t$ $=\Delta u_{\varepsilon} - \varepsilon \nabla \cdot ( u_\varepsilon \nabla…
This work considers the Keller-Segel consumption system \begin{eqnarray*} \left\{ \begin{array}{llll} u_t=\Delta (u\phi(v))+au-bu^\gamma,\quad &x\in \Omega,\quad t>0,\\ v_t=\Delta v-uv,\quad &x\in\Omega,\quad t>0 \end{array} \right.…